STRINGSTRING
SEMA3A SEMA3A NOLC1 NOLC1 EFNB1 EFNB1 SEMA3G SEMA3G SEMA4F SEMA4F FAM83D FAM83D SEMA5B SEMA5B SEMA3B SEMA3B SEMA4C SEMA4C DLG5 DLG5 TAPT1 TAPT1 HEYL HEYL SEMA4B SEMA4B HMGA2 HMGA2 NOG NOG FGF10 FGF10 TGFB2 TGFB2 ENSPCOP00000001724 ENSPCOP00000001724 FGFR1 FGFR1 HAND2 HAND2 HEY1 HEY1 SEMA6B SEMA6B LOXL3 LOXL3 FLNA FLNA BMP7 BMP7 LEF1 LEF1 NOTCH1 NOTCH1 HIF1A HIF1A JAG1 JAG1 OVOL2 OVOL2 ENSPCOP00000005343 ENSPCOP00000005343 ENSPCOP00000005396 ENSPCOP00000005396 EOMES EOMES AKNA AKNA PDCD6 PDCD6 WNT11 WNT11 DDX17 DDX17 CDH2 CDH2 EDN1 EDN1 PHACTR4 PHACTR4 WNT16 WNT16 ENSPCOP00000008407 ENSPCOP00000008407 FRZB FRZB SNAI2 SNAI2 NRG1 NRG1 OTUD5 OTUD5 HNRNPAB HNRNPAB POLR1B POLR1B MEF2C MEF2C ENSPCOP00000009216 ENSPCOP00000009216 SEMA3E SEMA3E TASOR TASOR CYP26C1 CYP26C1 ENSPCOP00000011221 ENSPCOP00000011221 SEMA4D SEMA4D TCOF1 TCOF1 NRTN NRTN ROCK2 ROCK2 BMPR1A BMPR1A ZFP64 ZFP64 FGF8 FGF8 ISL1 ISL1 SEMA5A SEMA5A RANBP3L RANBP3L GBX2 GBX2 RPS7 RPS7 EDNRB EDNRB FBXL17 FBXL17 HAS2 HAS2 EPB41L5 EPB41L5 CUL7 CUL7 LOC105817738 LOC105817738 EFNA1 EFNA1 LAMA5 LAMA5 PAX2 PAX2 AMER1 AMER1 TGFBR3 TGFBR3 NRP2 NRP2 ACVR1 ACVR1 NRP1 NRP1 FGF19 FGF19 TBX1 TBX1 SNAI1 SNAI1 PHOX2B PHOX2B ENSPCOP00000018033 ENSPCOP00000018033 SEMA7A SEMA7A HGF HGF TGFBR1 TGFBR1 EXT1 EXT1 SEMA4A SEMA4A FOXF2 FOXF2 RDH10 RDH10 RADIL RADIL WWTR1 WWTR1 ALX1 ALX1 PPP3R1 PPP3R1 SOX10 SOX10 BCL2 BCL2 ENG ENG LOXL2 LOXL2 PITX2 PITX2 TGFBR3L TGFBR3L WNT4 WNT4 SOX8 SOX8 CITED2 CITED2 GDNF GDNF KITLG KITLG SEMA4G SEMA4G RFLNB RFLNB CTNNB1 CTNNB1 GSK3B GSK3B ANXA6 ANXA6 TGFB1 TGFB1 PEF1 PEF1 SEMA6C SEMA6C DDX5 DDX5 CORO1C CORO1C RET RET DACT3 DACT3 FAM172A FAM172A FOLR1 FOLR1 FN1 FN1 SMAD4 SMAD4 ADAM15 ADAM15 SIX2 SIX2 OSR1 OSR1 ALDH1A2 ALDH1A2 EDN3 EDN3 SPRY1 SPRY1 FOXC2 FOXC2 RTN4 RTN4 SMO SMO SEMA3F SEMA3F BMP4 BMP4 FOXC1 FOXC1 S100A4 S100A4 NOTCH4 NOTCH4 OLFM1 OLFM1 SOX9 SOX9 ENSPCOP00000029403 ENSPCOP00000029403 WNT10A WNT10A EDNRA EDNRA SEMA6A SEMA6A MSX1 MSX1 MAPK1 MAPK1 HTR2B HTR2B SOX11 SOX11 FGFR2 FGFR2 WNT2 WNT2 HEY2 HEY2 SFRP1 SFRP1 BMP2 BMP2 TBX20 TBX20 TRIM28 TRIM28 MAPK3 MAPK3 LRP6 LRP6 STAT1 STAT1 GSC GSC ROCK1 ROCK1 WNT5A WNT5A TCF21 TCF21
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (619 aa)
NOLC1LisH domain-containing protein. (665 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (777 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
FAM83DFamily with sequence similarity 83 member D. (585 aa)
SEMA5BSemaphorin 5B. (1173 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (749 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
TAPT1Transmembrane anterior posterior transformation 1. (567 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (828 aa)
HMGA2Uncharacterized protein. (117 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSPCOP0000000172440S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (207 aa)
FGFR1Fibroblast growth factor receptor. (846 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (624 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
FLNAFilamin A. (2647 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
LEF1Lymphoid enhancer binding factor 1. (432 aa)
NOTCH1Notch receptor 1. (2420 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
OVOL2Ovo like zinc finger 2. (276 aa)
ENSPCOP00000005343Uncharacterized protein. (159 aa)
ENSPCOP00000005396Uncharacterized protein. (130 aa)
EOMESEomesodermin. (705 aa)
AKNAAT-hook transcription factor. (1408 aa)
PDCD6Programmed cell death 6. (191 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (735 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
EDN1Endothelin 1. (193 aa)
PHACTR4Phosphatase and actin regulator. (702 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ENSPCOP00000008407Sema domain-containing protein; Belongs to the semaphorin family. (244 aa)
FRZBFrizzled related protein. (325 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
NRG1Neuregulin 1. (710 aa)
OTUD5OTU deubiquitinase 5. (590 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (328 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1183 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ENSPCOP00000009216Uncharacterized protein. (204 aa)
SEMA3ESema domain-containing protein; Belongs to the semaphorin family. (390 aa)
TASORTranscription activation suppressor. (1572 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
ENSPCOP00000011221FERM domain-containing protein. (471 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1426 aa)
NRTNNeurturin. (197 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (484 aa)
ZFP64ZFP64 zinc finger protein. (597 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SEMA5ASemaphorin 5A. (1074 aa)
RANBP3LRAN binding protein 3 like. (489 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (485 aa)
FBXL17F-box and leucine rich repeat protein 17. (698 aa)
HAS2Hyaluronan synthase 2. (552 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (731 aa)
CUL7Cullin 7; Belongs to the cullin family. (1762 aa)
LOC105817738SRP40_C domain-containing protein. (706 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
LAMA5Laminin subunit alpha 5. (3694 aa)
PAX2Paired box 2. (417 aa)
AMER1APC membrane recruitment protein 1. (796 aa)
TGFBR3Transforming growth factor beta receptor 3. (851 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (932 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
TBX1T-box transcription factor 1. (489 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
PHOX2BPaired like homeobox 2B. (305 aa)
ENSPCOP00000018033HH_signal domain-containing protein. (110 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (703 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
FOXF2Forkhead box F2. (405 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
RADILRap associating with DIL domain. (1070 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
ALX1ALX homeobox 1. (326 aa)
PPP3R1Uncharacterized protein. (189 aa)
SOX10SRY-box transcription factor 10. (468 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
ENGEndoglin. (657 aa)
LOXL2Lysyl oxidase like 2. (775 aa)
PITX2Homeobox protein. (325 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (313 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SOX8SRY-box transcription factor 8. (462 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (844 aa)
RFLNBRefilin B. (146 aa)
CTNNB1Catenin beta 1. (781 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
ANXA6Annexin. (650 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PEF1Penta-EF-hand domain containing 1. (274 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (963 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1079 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (631 aa)
FAM172AFamily with sequence similarity 172 member A. (284 aa)
FOLR1Folate receptor alpha. (257 aa)
FN1Fibronectin 1. (2290 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ADAM15ADAM metallopeptidase domain 15. (859 aa)
SIX2SIX homeobox 2. (296 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
EDN3Endothelin 3. (224 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
FOXC2Forkhead box C2. (503 aa)
RTN4Reticulon. (1195 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (786 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
FOXC1Forkhead box C1. (535 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
NOTCH4Notch receptor 4. (2000 aa)
OLFM1Olfactomedin 1. (485 aa)
SOX9SRY-box transcription factor 9. (505 aa)
ENSPCOP00000029403Protein kinase domain-containing protein. (429 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
SOX11Transcription factor SOX. (442 aa)
FGFR2Fibroblast growth factor receptor. (797 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TBX20T-box transcription factor 20. (447 aa)
TRIM28Tripartite motif containing 28. (833 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1579 aa)
STAT1Signal transducer and activator of transcription. (794 aa)
GSCGoosecoid homeobox. (256 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TCF21Transcription factor 21. (179 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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