STRINGSTRING
LPAR1 LPAR1 GPSM3 GPSM3 SERPINE1 SERPINE1 DSCAM DSCAM MDK MDK EDN2 EDN2 NEDD9 NEDD9 TREM2 TREM2 STX3 STX3 TNFSF14 TNFSF14 SLIT2 SLIT2 ANO6 ANO6 IL16 IL16 PRKD2 PRKD2 MSTN MSTN ENSPCOP00000014885 ENSPCOP00000014885 BMPR2 BMPR2 AZU1 AZU1 CAMK1D CAMK1D IL12A IL12A NRP1 NRP1 CX3CR1 CX3CR1 TNFSF18 TNFSF18 RARRES2 RARRES2 CCL26 CCL26 PTN PTN NCKAP1L NCKAP1L SLAMF1 SLAMF1 ADAM10 ADAM10 DNM1L DNM1L VEGFC VEGFC CMKLR1 CMKLR1 CXCR3 CXCR3 ENSPCOP00000021694 ENSPCOP00000021694 NTF3 NTF3 PLA2G7 PLA2G7 MET MET SMAD3 SMAD3 LOC105821125 LOC105821125 TIRAP TIRAP TGFB1 TGFB1 SMOC2 SMOC2 CCL19 CCL19 VEGFA VEGFA CXCL10 CXCL10 F3 F3 MCU MCU CXCL8 CXCL8 THBS1 THBS1 FN1 FN1 TMEM102 TMEM102 MOSPD2 MOSPD2 CREB3 CREB3 PTK2 PTK2 EDN3 EDN3 CSF1R CSF1R ITGA2 ITGA2 THBS4 THBS4 DEF6 DEF6 NTRK3 NTRK3 S1PR1 S1PR1 PTK2B PTK2B CALR CALR IL6R IL6R CCL1 CCL1 MAPK1 MAPK1 ADAM17 ADAM17 ARTN ARTN PDGFRB PDGFRB HSPB1 HSPB1 TRPV4 TRPV4 AKIRIN1 AKIRIN1 STK39 STK39 VEGFD VEGFD FGF18 FGF18 LBP LBP CCL27 CCL27 CCL21 CCL21 ENSPCOP00000000279 ENSPCOP00000000279 GAS6 GAS6 AGER AGER DEFB124 DEFB124 FGF10 FGF10 WNK1 WNK1 FGF16 FGF16 PRKD1 PRKD1 OXSR1 OXSR1 FGFR1 FGFR1 PRSS56 PRSS56 P2RX4 P2RX4 C1QBP C1QBP CCL5 CCL5 PDGFB PDGFB MEGF8 MEGF8 STX4 STX4 CXCL17 CXCL17 ZNF580 ZNF580 F7 F7 KDR KDR CXCL13 CXCL13 ENSPCOP00000005855 ENSPCOP00000005855 CXCL14 CXCL14 CSF1 CSF1 CXCL12 CXCL12 LGMN LGMN S100A14 S100A14 PPM1F PPM1F DAPK2 DAPK2 WNT5A WNT5A MAPK3 MAPK3 VEGFB VEGFB AIF1 AIF1 SWAP70 SWAP70 IL23A IL23A CD74 CD74 CASR CASR PGF PGF CCR7 CCR7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
GPSM3G protein signaling modulator 3. (160 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
DSCAMDS cell adhesion molecule. (1917 aa)
MDKMidkine. (143 aa)
EDN2Endothelin 2. (178 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (290 aa)
TNFSF14TNF superfamily member 14. (241 aa)
SLIT2Slit guidance ligand 2. (1423 aa)
ANO6Anoctamin. (932 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1189 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
MSTNMyostatin. (376 aa)
ENSPCOP00000014885Uncharacterized protein. (57 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
AZU1Azurocidin 1. (250 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
TNFSF18TNF superfamily member 18. (199 aa)
RARRES2Retinoic acid receptor responder 2. (163 aa)
CCL26C-C motif chemokine. (92 aa)
PTNPleiotrophin. (177 aa)
NCKAP1LNCK associated protein 1 like. (1138 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (368 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (367 aa)
CMKLR1Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
ENSPCOP00000021694Uncharacterized protein. (146 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (442 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1397 aa)
SMAD3Mothers against decapentaplegic homolog. (443 aa)
LOC105821125SCY domain-containing protein. (114 aa)
TIRAPTIR domain containing adaptor protein. (198 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SMOC2SPARC related modular calcium binding 2. (457 aa)
CCL19C-C motif chemokine. (108 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
CXCL10C-X-C motif chemokine. (98 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (294 aa)
MCUMitochondrial calcium uniporter. (350 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
THBS1Thrombospondin 1. (1185 aa)
FN1Fibronectin 1. (2290 aa)
TMEM102Transmembrane protein 102. (510 aa)
MOSPD2Motile sperm domain containing 2. (519 aa)
CREB3cAMP responsive element binding protein 3. (373 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
EDN3Endothelin 3. (224 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1129 aa)
THBS4Thrombospondin 4. (959 aa)
DEF6DEF6 guanine nucleotide exchange factor. (512 aa)
NTRK3Tyrosine-protein kinase receptor. (865 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
CALRCalreticulin. (417 aa)
IL6RInterleukin 6 receptor. (469 aa)
CCL1C-C motif chemokine ligand 1. (96 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ADAM17ADAM metallopeptidase domain 17. (757 aa)
ARTNArtemin. (229 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (206 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
AKIRIN1Akirin 1. (193 aa)
STK39Serine/threonine kinase 39. (522 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (319 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LBPLipopolysaccharide binding protein. (481 aa)
CCL27C-C motif chemokine ligand 27. (117 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
ENSPCOP00000000279Uncharacterized protein. (118 aa)
GAS6Growth arrest specific 6. (648 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
DEFB124Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (71 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNK1WNK lysine deficient protein kinase 1. (2808 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
OXSR1Oxidative stress responsive kinase 1. (527 aa)
FGFR1Fibroblast growth factor receptor. (846 aa)
PRSS56Serine protease 56; Belongs to the peptidase S1 family. (605 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
C1QBPUncharacterized protein. (281 aa)
CCL5C-C motif chemokine. (91 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
MEGF8Multiple EGF like domains 8. (2804 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (298 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
ZNF580Zinc finger protein 580. (172 aa)
F7Coagulation factor VII. (441 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
CXCL13C-X-C motif chemokine. (110 aa)
ENSPCOP00000005855Uncharacterized protein. (259 aa)
CXCL14C-X-C motif chemokine ligand 14. (111 aa)
CSF1Colony stimulating factor 1. (438 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (159 aa)
LGMNLegumain. (433 aa)
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (444 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
IL23AInterleukin 23 subunit alpha. (190 aa)
CD74CD74 molecule. (298 aa)
CASRCalcium sensing receptor. (1076 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (220 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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