STRINGSTRING
ENSPCOP00000004143 ENSPCOP00000004143 GRPEL2 GRPEL2 RNF207 RNF207 PRKN PRKN SLC12A2 SLC12A2 LOC105816498 LOC105816498 SUGT1 SUGT1 AHSA1 AHSA1 DNAJB9 DNAJB9 DNAJC13 DNAJC13 SOD1 SOD1 DNAJC3 DNAJC3 CNPY2 CNPY2 GNB5 GNB5 ENSPCOP00000014605 ENSPCOP00000014605 DNAJB2 DNAJB2 TIMM10 TIMM10 DNAJB1 DNAJB1 TIMM9 TIMM9 DNAJC12 DNAJC12 ENSPCOP00000013570 ENSPCOP00000013570 FNIP2 FNIP2 TSACC TSACC CP CP ATP1A1 ATP1A1 DNAJB4 DNAJB4 BIN1 BIN1 SYVN1 SYVN1 CDC37 CDC37 DNLZ DNLZ PFDN6 PFDN6 SDF2L1 SDF2L1 FGB FGB DNAJA2 DNAJA2 PIH1D3 PIH1D3 FICD FICD ATP7A ATP7A DNAJA4 DNAJA4 SLC25A17 SLC25A17 KSR1 KSR1 FN1 FN1 DNAJA1 DNAJA1 ENSPCOP00000025432 ENSPCOP00000025432 VWF VWF DNAJB13 DNAJB13 CFTR CFTR SACS SACS ENSPCOP00000007319 ENSPCOP00000007319 TBCD TBCD CDC25A CDC25A PACRG PACRG PTGES3L PTGES3L DNAJB6 DNAJB6 BAG5 BAG5 CDC37L1 CDC37L1 CDKN1B CDKN1B SCARB2 SCARB2 ENSPCOP00000028930 ENSPCOP00000028930 ENSPCOP00000005005 ENSPCOP00000005005 ENSPCOP00000004977 ENSPCOP00000004977 HYOU1 HYOU1 TG TG PDPN PDPN UBL4A UBL4A AMFR AMFR DNAJB5 DNAJB5 DNAJC9 DNAJC9 BAX BAX TIMM44 TIMM44 USP19 USP19 PACRGL PACRGL ATP1A3 ATP1A3 ALB ALB BAG1 BAG1 BAK1 BAK1 TP53 TP53 ATP1A2 ATP1A2 HSPE1 HSPE1 DNAJC1 DNAJC1 ENSPCOP00000031075 ENSPCOP00000031075 BAG4 BAG4 ENSPCOP00000030811 ENSPCOP00000030811 ERP29 ERP29 GET4 GET4 ENSPCOP00000003468 ENSPCOP00000003468 GAK GAK CLU CLU ENSPCOP00000002776 ENSPCOP00000002776 LRP2 LRP2 ENSPCOP00000002376 ENSPCOP00000002376 ENSPCOP00000002275 ENSPCOP00000002275 TSC1 TSC1 TBCA TBCA GRPEL1 GRPEL1 GRN GRN HSPB6 HSPB6 STUB1 STUB1 USP13 USP13 ENSPCOP00000000067 ENSPCOP00000000067 BAG2 BAG2 BAG3 BAG3 WRAP53 WRAP53 HSCB HSCB LOC105823578 LOC105823578
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000004143Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (136 aa)
GRPEL2GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (225 aa)
RNF207Ring finger protein 207. (634 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
SLC12A2Solute carrier family 12 member 2. (1153 aa)
LOC105816498Uncharacterized protein. (3898 aa)
SUGT1Uncharacterized protein. (333 aa)
AHSA1Activator of HSP90 ATPase activity 1. (338 aa)
DNAJB9DnaJ heat shock protein family (Hsp40) member B9. (222 aa)
DNAJC13DnaJ heat shock protein family (Hsp40) member C13. (2166 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
CNPY2Saposin B-type domain-containing protein. (182 aa)
GNB5G protein subunit beta 5. (395 aa)
ENSPCOP00000014605Aha1_N domain-containing protein. (122 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (324 aa)
TIMM10Translocase of inner mitochondrial membrane 10. (90 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
TIMM9Translocase of inner mitochondrial membrane 9. (89 aa)
DNAJC12DnaJ heat shock protein family (Hsp40) member C12. (227 aa)
ENSPCOP00000013570Uncharacterized protein. (83 aa)
FNIP2Folliculin interacting protein 2. (1114 aa)
TSACCTSSK6 activating cochaperone. (126 aa)
CPCeruloplasmin; Belongs to the multicopper oxidase family. (1066 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (344 aa)
BIN1Bridging integrator 1. (594 aa)
SYVN1Synoviolin 1. (622 aa)
CDC37Cell division cycle 37. (376 aa)
DNLZDNL-type zinc finger. (167 aa)
PFDN6Prefoldin subunit 6. (129 aa)
SDF2L1Stromal cell derived factor 2 like 1. (221 aa)
FGBFibrinogen beta chain. (492 aa)
DNAJA2DnaJ heat shock protein family (Hsp40) member A2. (412 aa)
PIH1D3PIH1 domain containing 3. (214 aa)
FICDFIC domain containing. (458 aa)
ATP7AATPase copper transporting alpha. (1502 aa)
DNAJA4DnaJ heat shock protein family (Hsp40) member A4. (426 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa)
KSR1Kinase suppressor of ras 1. (849 aa)
FN1Fibronectin 1. (2290 aa)
DNAJA1DnaJ heat shock protein family (Hsp40) member A1. (397 aa)
ENSPCOP00000025432Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
VWFVon Willebrand factor. (2807 aa)
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (316 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1426 aa)
SACSSacsin molecular chaperone. (4532 aa)
ENSPCOP00000007319Uncharacterized protein. (148 aa)
TBCDTubulin folding cofactor D. (1226 aa)
CDC25ACell division cycle 25A. (527 aa)
PACRGParkin coregulated. (257 aa)
PTGES3LProstaglandin E synthase 3 like. (142 aa)
DNAJB6DnaJ heat shock protein family (Hsp40) member B6. (327 aa)
BAG5BCL2 associated athanogene 5. (470 aa)
CDC37L1Cell division cycle 37 like 1. (337 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
ENSPCOP00000028930Uncharacterized protein. (241 aa)
ENSPCOP00000005005Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
ENSPCOP00000004977zf-Tim10_DDP domain-containing protein. (84 aa)
HYOU1Hypoxia up-regulated 1. (997 aa)
TGThyroglobulin. (2704 aa)
PDPNPodoplanin. (211 aa)
UBL4AUbiquitin like 4A. (169 aa)
AMFRAutocrine motility factor receptor. (643 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (461 aa)
DNAJC9DnaJ heat shock protein family (Hsp40) member C9. (260 aa)
BAXBCL2 associated X, apoptosis regulator. (199 aa)
TIMM44Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (452 aa)
USP19Ubiquitin specific peptidase 19. (1385 aa)
PACRGLParkin coregulated like. (173 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1080 aa)
ALBAlbumin. (494 aa)
BAG1BCL2 associated athanogene 1. (306 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
HSPE1Uncharacterized protein; Belongs to the GroES chaperonin family. (103 aa)
DNAJC1DnaJ heat shock protein family (Hsp40) member C1. (491 aa)
ENSPCOP00000031075CR-type domain-containing protein. (300 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
ENSPCOP00000030811Sod_Cu domain-containing protein. (132 aa)
ERP29Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (260 aa)
GET4Guided entry of tail-anchored proteins factor 4. (328 aa)
ENSPCOP00000003468DUF3456 domain-containing protein. (116 aa)
GAKCyclin G associated kinase. (1298 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (450 aa)
ENSPCOP00000002776Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
LRP2LDL receptor related protein 2. (4654 aa)
ENSPCOP00000002376Uncharacterized protein. (341 aa)
ENSPCOP00000002275Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
TSC1TSC complex subunit 1. (1164 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (131 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
GRNGranulin precursor. (591 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (162 aa)
STUB1STIP1 homology and U-box containing protein 1. (304 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
ENSPCOP00000000067Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (133 aa)
BAG2BCL2 associated athanogene 2. (211 aa)
BAG3BCL2 associated athanogene 3. (577 aa)
WRAP53WD repeat containing antisense to TP53. (540 aa)
HSCBHscB mitochondrial iron-sulfur cluster cochaperone. (211 aa)
LOC105823578Uncharacterized protein. (375 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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