STRINGSTRING
ENSPCOP00000013591 ENSPCOP00000013591 RELA RELA AR AR RPS3 RPS3 ENSPCOP00000031861 ENSPCOP00000031861 CARD9 CARD9 NOD1 NOD1 PYCARD PYCARD TNFSF11 TNFSF11 RIPK3 RIPK3 TRAF5 TRAF5 IL18R1 IL18R1 PIDD1 PIDD1 MALT1 MALT1 MYD88 MYD88 STAT3 STAT3 ZBTB7A ZBTB7A CHUK CHUK BTK BTK PRKCB PRKCB ENSPCOP00000029405 ENSPCOP00000029405 IRAK1 IRAK1 NOD2 NOD2 MAP3K13 MAP3K13 RBCK1 RBCK1 TRAF1 TRAF1 AMH AMH FLOT2 FLOT2 ENSPCOP00000023239 ENSPCOP00000023239 NPM1 NPM1 RIPK1 RIPK1 ENSPCOP00000024480 ENSPCOP00000024480 RIPK2 RIPK2 ENSPCOP00000024882 ENSPCOP00000024882 CAV1 CAV1 SLCO3A1 SLCO3A1 RHEBL1 RHEBL1 CD40 CD40 TICAM1 TICAM1 LAMTOR5 LAMTOR5 TRIM25 TRIM25 TFRC TFRC LOC105822932 LOC105822932 PRKCQ PRKCQ CRNN CRNN ANKRD42 ANKRD42 IKBKG IKBKG ENSPCOP00000027398 ENSPCOP00000027398 TERF2IP TERF2IP LOC105826437 LOC105826437 AIM2 AIM2 CARD14 CARD14 ENSPCOP00000000471 ENSPCOP00000000471 TRIM8 TRIM8 AGER AGER RIPK4 RIPK4 S100A8 S100A8 TRAF6 TRAF6 PRKCZ PRKCZ TRIM5 TRIM5 TRIM32 TRIM32 PRKD1 PRKD1 DHX33 DHX33 CLU CLU TRAPPC9 TRAPPC9 MTPN MTPN IL18RAP IL18RAP RPS6KA5 RPS6KA5 TRIML1 TRIML1 FLOT1 FLOT1 ROR1 ROR1 EDA EDA LTF LTF TRIM52 TRIM52 PRKCI PRKCI MID2 MID2 ALK ALK ENSPCOP00000005894 ENSPCOP00000005894 ENSPCOP00000006033 ENSPCOP00000006033 EIF2AK2 EIF2AK2 TRIM6 TRIM6 MTDH MTDH TLR9 TLR9 RPS6KA4 RPS6KA4 ITGB2 ITGB2 CIB1 CIB1 WNT5A WNT5A RNF25 RNF25 ENSPCOP00000008176 ENSPCOP00000008176 TNFRSF11A TNFRSF11A NTSR1 NTSR1 NTS NTS EDA2R EDA2R CD40LG CD40LG TLR3 TLR3 RNF31 RNF31 LOC105811124 LOC105811124 ARHGEF2 ARHGEF2 S100A12 S100A12 CD36 CD36 NTRK1 NTRK1 SPHK1 SPHK1 IL1B IL1B APP APP RTKN2 RTKN2 CAPN3 CAPN3 PLCG2 PLCG2 TRIM14 TRIM14 DHX9 DHX9 TRIM27 TRIM27 NLRP3 NLRP3 TRIM62 TRIM62 PRKD2 PRKD2 ENSPCOP00000013979 ENSPCOP00000013979 PSMA6 PSMA6 IL1RAP IL1RAP FER FER CLOCK CLOCK DDRGK1 DDRGK1 TRAF2 TRAF2 S100A9 S100A9 TNF TNF RAB7B RAB7B CARD11 CARD11 LOC105824240 LOC105824240 TRADD TRADD CX3CR1 CX3CR1 ERC1 ERC1 TRIM37 TRIM37 TNFSF18 TNFSF18 ADAM8 ADAM8 IRAK2 IRAK2 EP300 EP300 IRAK3 IRAK3 ENSPCOP00000020030 ENSPCOP00000020030 CX3CL1 CX3CL1 IKBKB IKBKB TRIML2 TRIML2 ENSPCOP00000022967 ENSPCOP00000022967 TIRAP TIRAP TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000013591Proteasome endopeptidase complex. (228 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
ARAndrogen receptor. (886 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
ENSPCOP00000031861Uncharacterized protein. (214 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (949 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (516 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (536 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
PIDD1P53-induced death domain protein 1. (915 aa)
MALT1MALT1 paracaspase. (787 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (582 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (682 aa)
BTKTyrosine-protein kinase. (647 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ENSPCOP00000029405UBIQUITIN_CONJUGAT_2 domain-containing protein. (155 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13. (958 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
TRAF1TNF receptor-associated factor. (415 aa)
AMHAnti-Mullerian hormone. (561 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ENSPCOP00000023239RING-type domain-containing protein. (105 aa)
NPM1Uncharacterized protein. (294 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
ENSPCOP00000024480Uncharacterized protein. (103 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
ENSPCOP00000024882Ribosomal_S3_C domain-containing protein. (231 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
SLCO3A1Solute carrier organic anion transporter family member. (643 aa)
RHEBL1RHEB like 1. (183 aa)
CD40CD40 molecule. (281 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (692 aa)
LAMTOR5Uncharacterized protein. (149 aa)
TRIM25Tripartite motif containing 25. (633 aa)
TFRCTransferrin receptor. (760 aa)
LOC105822932Uncharacterized protein. (91 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
CRNNCornulin. (386 aa)
ANKRD42Ankyrin repeat domain 42. (517 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa)
ENSPCOP00000027398KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (281 aa)
TERF2IPTERF2 interacting protein. (393 aa)
LOC105826437E3 ubiquitin-protein ligase TRIM32. (653 aa)
AIM2Absent in melanoma 2. (260 aa)
CARD14Caspase recruitment domain family member 14. (1008 aa)
ENSPCOP00000000471Uncharacterized protein. (96 aa)
TRIM8Tripartite motif containing 8. (551 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (814 aa)
S100A8S100 calcium binding protein A8; Belongs to the S-100 family. (89 aa)
TRAF6TNF receptor-associated factor. (498 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
TRIM5Uncharacterized protein. (482 aa)
TRIM32Uncharacterized protein. (653 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
DHX33DEAH-box helicase 33. (706 aa)
CLUClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (450 aa)
TRAPPC9Trafficking protein particle complex 9. (1148 aa)
MTPNMyotrophin. (118 aa)
IL18RAPInterleukin 18 receptor accessory protein. (480 aa)
RPS6KA5Ribosomal protein S6 kinase A5. (643 aa)
TRIML1Tripartite motif family like 1. (468 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
LTFLactotransferrin; Belongs to the transferrin family. (708 aa)
TRIM52Tripartite motif containing 52. (301 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (522 aa)
MID2Midline 2. (735 aa)
ALKTyrosine-protein kinase receptor. (1578 aa)
ENSPCOP00000005894Uncharacterized protein. (192 aa)
ENSPCOP00000006033Phospholipase A(2). (94 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (549 aa)
TRIM6Tripartite motif containing 6. (510 aa)
MTDHMetadherin. (580 aa)
TLR9TIR domain-containing protein. (1029 aa)
RPS6KA4Ribosomal protein S6 kinase. (764 aa)
ITGB2Integrin beta. (764 aa)
CIB1Calcium and integrin binding 1. (191 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
RNF25Ring finger protein 25. (457 aa)
ENSPCOP00000008176Proteasome subunit alpha type. (200 aa)
TNFRSF11ATNF receptor superfamily member 11a. (584 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (402 aa)
NTSNeurotensin. (170 aa)
EDA2REctodysplasin A2 receptor. (314 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
RNF31Uncharacterized protein. (1072 aa)
LOC105811124Uncharacterized protein. (256 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1013 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SPHK1Sphingosine kinase 1. (469 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
APPAmyloid beta precursor protein. (772 aa)
RTKN2Rhotekin 2. (609 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
TRIM14Tripartite motif containing 14. (447 aa)
DHX9DExH-box helicase 9. (1262 aa)
TRIM27Tripartite motif containing 27. (513 aa)
NLRP3NLR family pyrin domain containing 3. (1036 aa)
TRIM62Tripartite motif containing 62. (475 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
ENSPCOP00000013979Uncharacterized protein. (488 aa)
PSMA6Proteasome subunit alpha type. (145 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
CLOCKClock circadian regulator. (745 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
S100A9S100 calcium binding protein A9; Belongs to the S-100 family. (154 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
CARD11Caspase recruitment domain family member 11. (1125 aa)
LOC105824240Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (248 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (737 aa)
TRIM37Tripartite motif containing 37. (962 aa)
TNFSF18TNF superfamily member 18. (199 aa)
ADAM8ADAM metallopeptidase domain 8. (812 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (532 aa)
EP300E1A binding protein p300. (2424 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (505 aa)
ENSPCOP00000020030KH type-2 domain-containing protein. (93 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (405 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (747 aa)
TRIML2Tripartite motif family like 2. (437 aa)
ENSPCOP00000022967Uncharacterized protein. (277 aa)
TIRAPTIR domain containing adaptor protein. (198 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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