STRINGSTRING
BRAF BRAF HPCAL1 HPCAL1 LGMN LGMN CPNE6 CPNE6 SCN5A SCN5A JUND JUND ALG2 ALG2 PDCD6 PDCD6 SYT12 SYT12 SYT11 SYT11 RASGRP2 RASGRP2 ADCY1 ADCY1 CAPN3 CAPN3 SLC25A24 SLC25A24 FOS FOS TRPM2 TRPM2 SLC25A23 SLC25A23 NCSTN NCSTN IQGAP1 IQGAP1 KCNMB3 KCNMB3 NLGN1 NLGN1 NEUROD2 NEUROD2 ANXA11 ANXA11 FOSB FOSB P2RX5 P2RX5 TRPC1 TRPC1 SYT6 SYT6 CPNE5 CPNE5 HPCA HPCA PPP3CA PPP3CA JUNB JUNB ALOX15 ALOX15 ITPKC ITPKC CPNE2 CPNE2 FGB FGB WNT5A WNT5A ADD1 ADD1 CPNE7 CPNE7 MEF2C MEF2C TNNT2 TNNT2 SMPD1 SMPD1 SDC1 SDC1 FGA FGA PRKAA1 PRKAA1 PEF1 PEF1 EEF2K EEF2K RYR3 RYR3 SYT13 SYT13 AQP3 AQP3 ASPH ASPH CAMK2D CAMK2D ENTPD6 ENTPD6 MEF2A MEF2A DPEP1 DPEP1 TRPC3 TRPC3 PENK PENK GIPR GIPR SYT4 SYT4 CPNE4 CPNE4 SLC25A13 SLC25A13 MCOLN1 MCOLN1 KCNMB2 KCNMB2 KCNMB1 KCNMB1 HNRNPD HNRNPD TSHB TSHB SYT8 SYT8 ITPR3 ITPR3 MTTP MTTP CPNE3 CPNE3 RASAL1 RASAL1 LOC105807051 LOC105807051 SYT15 SYT15 SLC25A12 SLC25A12 MNAT1 MNAT1 KCNMB4 KCNMB4 PKD2 PKD2 PPIF PPIF INHBB INHBB SYT9 SYT9 CPNE8 CPNE8 DMTN DMTN PCSK1 PCSK1 FGG FGG CACNG2 CACNG2 NRXN1 NRXN1 RYR1 RYR1 ADCY8 ADCY8 PLCG2 PLCG2 SYT2 SYT2 CASR CASR ADGRV1 ADGRV1 ALOX5AP ALOX5AP ACER1 ACER1 RYR2 RYR2 CLIC4 CLIC4 CARF CARF KCNIP2 KCNIP2 THBS1 THBS1 ENSPCOP00000024844 ENSPCOP00000024844 CAV1 CAV1 KCNMA1 KCNMA1 KCNB1 KCNB1 AHCYL1 AHCYL1 SYT5 SYT5 ENSPCOP00000026958 ENSPCOP00000026958 GPLD1 GPLD1 PRKAA2 PRKAA2 SYT3 SYT3 CRHBP CRHBP S100A16 S100A16 ENSPCOP00000027736 ENSPCOP00000027736 PTK2B PTK2B HOMER1 HOMER1 ECT2 ECT2 SLC6A1 SLC6A1 CPNE9 CPNE9 SYT7 SYT7 P2RX7 P2RX7 CHP2 CHP2 BAD BAD NEDD4 NEDD4 GUCA1A GUCA1A ITPKB ITPKB ITPKA ITPKA STIM1 STIM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
HPCAL1Hippocalcin like 1. (199 aa)
LGMNLegumain. (433 aa)
CPNE6Copine 6. (608 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (348 aa)
ALG2ALG2 alpha-1,3/1,6-mannosyltransferase. (418 aa)
PDCD6Programmed cell death 6. (191 aa)
SYT12Synaptotagmin 12. (421 aa)
SYT11Synaptotagmin 11. (431 aa)
RASGRP2RAS guanyl releasing protein 2. (611 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1119 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (821 aa)
SLC25A24Solute carrier family 25 member 24; Belongs to the mitochondrial carrier (TC 2.A.29) family. (451 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (381 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1539 aa)
SLC25A23Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (468 aa)
NCSTNNicastrin. (708 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1400 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (277 aa)
NLGN1Neuroligin 1. (823 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
ANXA11Annexin. (504 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
SYT6Synaptotagmin 6. (528 aa)
CPNE5Copine 5. (575 aa)
HPCAHippocalcin. (193 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (682 aa)
CPNE2Copine 2. (548 aa)
FGBFibrinogen beta chain. (492 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ADD1Adducin 1. (751 aa)
CPNE7Copine 7. (599 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
TNNT2Troponin T2, cardiac type. (300 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
FGAFib_alpha domain-containing protein. (649 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PEF1Penta-EF-hand domain containing 1. (274 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
RYR3Ryanodine receptor 3. (4760 aa)
SYT13Synaptotagmin 13. (426 aa)
AQP3Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa)
ASPHAspartate beta-hydroxylase. (687 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (484 aa)
MEF2AMyocyte enhancer factor 2A. (495 aa)
DPEP1Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (408 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
PENKProenkephalin. (267 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
SYT4Synaptotagmin 4. (423 aa)
CPNE4Copine 4. (575 aa)
SLC25A13Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (673 aa)
MCOLN1Mucolipin 1. (569 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (355 aa)
TSHBThyroid stimulating hormone subunit beta. (138 aa)
SYT8Synaptotagmin 8. (394 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
MTTPMicrosomal triglyceride transfer protein. (776 aa)
CPNE3Copine 3. (478 aa)
RASAL1RAS protein activator like 1. (799 aa)
LOC105807051Uncharacterized protein. (802 aa)
SYT15Uncharacterized protein. (456 aa)
SLC25A12Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (679 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (963 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa)
INHBBInhibin subunit beta B. (408 aa)
SYT9Synaptotagmin 9. (491 aa)
CPNE8Copine 8. (542 aa)
DMTNDematin actin binding protein. (412 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)
FGGFibrinogen gamma chain. (456 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
NRXN1Neurexin 1. (1449 aa)
RYR1Ryanodine receptor 1. (4928 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
SYT2Synaptotagmin 2. (419 aa)
CASRCalcium sensing receptor. (1076 aa)
ADGRV1GPS domain-containing protein. (5403 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (217 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
RYR2Ryanodine receptor 2. (4825 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
CARFCalcium responsive transcription factor. (630 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
THBS1Thrombospondin 1. (1185 aa)
ENSPCOP00000024844Uncharacterized protein. (639 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
SYT5Synaptotagmin 5. (386 aa)
ENSPCOP00000026958Uncharacterized protein. (5601 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (813 aa)
PRKAA2Non-specific serine/threonine protein kinase. (553 aa)
SYT3Synaptotagmin 3. (590 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
S100A16Protein S100; Belongs to the S-100 family. (104 aa)
ENSPCOP00000027736G_PROTEIN_RECEP_F2_4 domain-containing protein. (334 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
HOMER1Homer scaffold protein 1. (329 aa)
ECT2Epithelial cell transforming 2. (598 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
CPNE9Copine family member 9. (553 aa)
SYT7Synaptotagmin 7. (686 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CHP2Calcineurin like EF-hand protein 2. (196 aa)
BADBCL2 associated agonist of cell death. (168 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1320 aa)
GUCA1AUncharacterized protein. (206 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
STIM1Stromal interaction molecule 1. (784 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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