STRINGSTRING
PLXNA2 PLXNA2 BMP7 BMP7 HOXA2 HOXA2 ECE1 ECE1 TGFB2 TGFB2 NOG NOG EDNRA EDNRA BMP4 BMP4 NKX3-1 NKX3-1 FOLR1 FOLR1 SIX4 SIX4 PTCH1 PTCH1 NKX2-6 NKX2-6 TGFBR1 TGFBR1 TBX1 TBX1 ACVR1 ACVR1 NKX2-5 NKX2-5 BMPR2 BMPR2 RIPPLY3 RIPPLY3 ISL1 ISL1 FGF8 FGF8 BMPR1A BMPR1A BMP5 BMP5 GATA3 GATA3 EYA1 EYA1 ADGRF5 ADGRF5 EDN1 EDN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXNA2Plexin A2. (1909 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
HOXA2Homeobox A2. (375 aa)
ECE1Endothelin converting enzyme 1. (758 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
NKX3-1NK3 homeobox 1. (226 aa)
FOLR1Folate receptor alpha. (257 aa)
SIX4SIX homeobox 4. (782 aa)
PTCH1Patched 1. (1449 aa)
NKX2-6NK2 homeobox 6. (296 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (421 aa)
TBX1T-box transcription factor 1. (489 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (510 aa)
NKX2-5NK2 homeobox 5. (324 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
RIPPLY3Ripply transcriptional repressor 3. (168 aa)
ISL1ISL LIM homeobox 1. (349 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (484 aa)
BMP5Bone morphogenetic protein 5. (379 aa)
GATA3Uncharacterized protein. (444 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
ADGRF5Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1346 aa)
EDN1Endothelin 1. (193 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.