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KCNE4 KCNE4 WDR1 WDR1 KCNH2 KCNH2 CACNB3 CACNB3 SNTA1 SNTA1 KCNH6 KCNH6 NPPA NPPA SCN1B SCN1B FLNA FLNA CAV3 CAV3 CACNA2D1 CACNA2D1 AKAP6 AKAP6 SCN5A SCN5A NOS1AP NOS1AP ZMPSTE24 ZMPSTE24 AKAP7 AKAP7 CACNA1D CACNA1D ANK2 ANK2 RNF207 RNF207 KCNQ1 KCNQ1 AKAP9 AKAP9 SCN4B SCN4B YWHAE YWHAE CAV1 CAV1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (209 aa)
WDR1WD repeat domain 1. (606 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1148 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
SNTA1Syntrophin alpha 1. (505 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (991 aa)
NPPANatriuretic peptide A. (153 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
FLNAFilamin A. (2647 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (740 aa)
AKAP6A-kinase anchoring protein 6. (2315 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (507 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
AKAP7A-kinase anchoring protein 7. (295 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
ANK2Ankyrin 2. (3925 aa)
RNF207Ring finger protein 207. (634 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (545 aa)
AKAP9A-kinase anchoring protein 9. (3687 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (225 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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