43 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRHL2	Grainyhead like transcription factor 2. (625 aa)
	SOX9	SRY-box transcription factor 9. (505 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	SPRY2	Sprouty RTK signaling antagonist 2. (314 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)
	ENSPCOP00000025005	Uncharacterized protein. (351 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (302 aa)
	STK40	Serine/threonine kinase 40. (435 aa)
	DAG1	Dystroglycan 1. (895 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	ESRP2	Epithelial splicing regulatory protein 2. (715 aa)
	ENSPCOP00000020579	Uncharacterized protein. (737 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	SRF	Serum response factor. (508 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	ENSPCOP00000018033	HH_signal domain-containing protein. (110 aa)
	HOXA5	Homeobox A5. (270 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2924 aa)
	HHIP	Hedgehog interacting protein. (701 aa)
	RSPO2	R-spondin 2. (243 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	FOXA1	Forkhead box A1. (472 aa)
	YAP1	Uncharacterized protein. (504 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	SEC24B	SEC24 homolog B, COPII coat complex component. (1164 aa)
	FOXF1	Forkhead box F1. (381 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	TBX2	T-box transcription factor 2. (713 aa)
	LAMA1	Laminin subunit alpha 1. (2945 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (958 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (336 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	HMGA2	Uncharacterized protein. (117 aa)
	LIF	LIF interleukin 6 family cytokine. (202 aa)
	DLG5	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
	TCF21	Transcription factor 21. (179 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	FGFR2	Fibroblast growth factor receptor. (797 aa)
	SOX11	Transcription factor SOX. (442 aa)
	NKX2-1	NK2 homeobox 1. (401 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSPCOP00000028335	ENSPCOP00000022753	Bone morphogenetic protein 4.	Catenin beta 1.	0.472
BMP4	ENSPCOP00000018033	ENSPCOP00000028335	ENSPCOP00000018033	Bone morphogenetic protein 4.	HH_signal domain-containing protein.	0.640
BMP4	FGF10	ENSPCOP00000028335	ENSPCOP00000001047	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.517
BMP4	FGF8	ENSPCOP00000028335	ENSPCOP00000012774	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.470
BMP4	FGFR2	ENSPCOP00000028335	ENSPCOP00000030338	Bone morphogenetic protein 4.	Fibroblast growth factor receptor.	0.438
BMP4	FOXF1	ENSPCOP00000028335	ENSPCOP00000009002	Bone morphogenetic protein 4.	Forkhead box F1.	0.693
BMP4	NODAL	ENSPCOP00000028335	ENSPCOP00000010056	Bone morphogenetic protein 4.	Nodal growth differentiation factor.	0.651
BMP4	NOG	ENSPCOP00000028335	ENSPCOP00000000944	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.987
BMP4	SPRY2	ENSPCOP00000028335	ENSPCOP00000027194	Bone morphogenetic protein 4.	Sprouty RTK signaling antagonist 2.	0.414
BMP4	TBX2	ENSPCOP00000028335	ENSPCOP00000003789	Bone morphogenetic protein 4.	T-box transcription factor 2.	0.449
BMP4	TGFBR2	ENSPCOP00000028335	ENSPCOP00000001360	Bone morphogenetic protein 4.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.678
BMP4	WNT2	ENSPCOP00000028335	ENSPCOP00000030382	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.526
CELSR1	SEC24B	ENSPCOP00000016541	ENSPCOP00000009122	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	SEC24 homolog B, COPII coat complex component.	0.405
CTNNB1	BMP4	ENSPCOP00000022753	ENSPCOP00000028335	Catenin beta 1.	Bone morphogenetic protein 4.	0.472
CTNNB1	DLG5	ENSPCOP00000022753	ENSPCOP00000000171	Catenin beta 1.	Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.	0.481
CTNNB1	ENSPCOP00000018033	ENSPCOP00000022753	ENSPCOP00000018033	Catenin beta 1.	HH_signal domain-containing protein.	0.578
CTNNB1	ENSPCOP00000025005	ENSPCOP00000022753	ENSPCOP00000025005	Catenin beta 1.	Uncharacterized protein.	0.874
CTNNB1	FGF8	ENSPCOP00000022753	ENSPCOP00000012774	Catenin beta 1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.430
CTNNB1	FGFR2	ENSPCOP00000022753	ENSPCOP00000030338	Catenin beta 1.	Fibroblast growth factor receptor.	0.695
CTNNB1	FOXF1	ENSPCOP00000022753	ENSPCOP00000009002	Catenin beta 1.	Forkhead box F1.	0.428