16 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX9	SRY-box transcription factor 9. (505 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	LEF1	Lymphoid enhancer binding factor 1. (432 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	FOXF1	Forkhead box F1. (381 aa)
	RARG	Retinoic acid receptor gamma. (458 aa)
	HOXA5	Homeobox A5. (270 aa)
	ENSPCOP00000018033	HH_signal domain-containing protein. (110 aa)
	SRF	Serum response factor. (508 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	RARA	Retinoic acid receptor alpha. (472 aa)
	HYDIN	HYDIN axonemal central pair apparatus protein. (4933 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
	RSPO2	R-spondin 2. (243 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSPCOP00000028335	ENSPCOP00000022753	Bone morphogenetic protein 4.	Catenin beta 1.	0.472
BMP4	EDA	ENSPCOP00000028335	ENSPCOP00000005547	Bone morphogenetic protein 4.	Ectodysplasin A; Belongs to the tumor necrosis factor family.	0.402
BMP4	ENSPCOP00000018033	ENSPCOP00000028335	ENSPCOP00000018033	Bone morphogenetic protein 4.	HH_signal domain-containing protein.	0.640
BMP4	FOXF1	ENSPCOP00000028335	ENSPCOP00000009002	Bone morphogenetic protein 4.	Forkhead box F1.	0.693
BMP4	LEF1	ENSPCOP00000028335	ENSPCOP00000004506	Bone morphogenetic protein 4.	Lymphoid enhancer binding factor 1.	0.449
BMP4	TGFBR2	ENSPCOP00000028335	ENSPCOP00000001360	Bone morphogenetic protein 4.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.678
CTNNB1	BMP4	ENSPCOP00000022753	ENSPCOP00000028335	Catenin beta 1.	Bone morphogenetic protein 4.	0.472
CTNNB1	ENSPCOP00000018033	ENSPCOP00000022753	ENSPCOP00000018033	Catenin beta 1.	HH_signal domain-containing protein.	0.578
CTNNB1	FOXF1	ENSPCOP00000022753	ENSPCOP00000009002	Catenin beta 1.	Forkhead box F1.	0.428
CTNNB1	LEF1	ENSPCOP00000022753	ENSPCOP00000004506	Catenin beta 1.	Lymphoid enhancer binding factor 1.	0.999
CTNNB1	MAPK1	ENSPCOP00000022753	ENSPCOP00000029858	Catenin beta 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.683
CTNNB1	MAPK3	ENSPCOP00000022753	ENSPCOP00000008272	Catenin beta 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.735
CTNNB1	RARA	ENSPCOP00000022753	ENSPCOP00000023848	Catenin beta 1.	Retinoic acid receptor alpha.	0.608
CTNNB1	SOX9	ENSPCOP00000022753	ENSPCOP00000029276	Catenin beta 1.	SRY-box transcription factor 9.	0.857
CTNNB1	TGFBR2	ENSPCOP00000022753	ENSPCOP00000001360	Catenin beta 1.	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	0.645
EDA	BMP4	ENSPCOP00000005547	ENSPCOP00000028335	Ectodysplasin A; Belongs to the tumor necrosis factor family.	Bone morphogenetic protein 4.	0.402
ENSPCOP00000018033	BMP4	ENSPCOP00000018033	ENSPCOP00000028335	HH_signal domain-containing protein.	Bone morphogenetic protein 4.	0.640
ENSPCOP00000018033	CTNNB1	ENSPCOP00000018033	ENSPCOP00000022753	HH_signal domain-containing protein.	Catenin beta 1.	0.578
ENSPCOP00000018033	FOXF1	ENSPCOP00000018033	ENSPCOP00000009002	HH_signal domain-containing protein.	Forkhead box F1.	0.723
ENSPCOP00000018033	LEF1	ENSPCOP00000018033	ENSPCOP00000004506	HH_signal domain-containing protein.	Lymphoid enhancer binding factor 1.	0.403