STRINGSTRING
RBCK1 RBCK1 MUTYH MUTYH BIRC3 BIRC3 YBX3 YBX3 BOK BOK ADPRHL2 ADPRHL2 RNF31 RNF31 ARHGEF2 ARHGEF2 PELI1 PELI1 CASP2 CASP2 BIRC2 BIRC2 FADD FADD CASP8 CASP8 RIPK1 RIPK1 CAV1 CAV1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (549 aa)
BIRC3Baculoviral IAP repeat containing 3. (597 aa)
YBX3Y-box binding protein 3. (242 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
ADPRHL2ADP-ribosylhydrolase like 2. (365 aa)
RNF31Uncharacterized protein. (1072 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1013 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
BIRC2Baculoviral IAP repeat containing 2. (619 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.