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| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | IGFBP3 | Insulin like growth factor binding protein 3. (293 aa) |
| | SIRT6 | Sirtuin 6. (305 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) |
| | GUCA1A | Uncharacterized protein. (206 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (573 aa) |
| | ATP5IF1 | ATP synthase inhibitory factor subunit 1. (106 aa) |
| | FOXK1 | Forkhead box K1. (731 aa) |
| | FOXK2 | Forkhead box K2. (631 aa) |
| | GPD1 | Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa) |
| | ENSPCOP00000031271 | Uncharacterized protein. (492 aa) |
| | ENSPCOP00000031233 | Uncharacterized protein. (318 aa) |
| | ARNT | Aryl hydrocarbon receptor nuclear translocator. (748 aa) |
| | CLYBL | Citrate lyase beta like. (340 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (613 aa) |
| | BMP2 | Bone morphogenetic protein 2. (395 aa) |
| | ENSPCOP00000030811 | Sod_Cu domain-containing protein. (132 aa) |
| | POR | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (681 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (440 aa) |
| | BAD | BCL2 associated agonist of cell death. (168 aa) |
| | C1QTNF12 | C1q and TNF related 12. (294 aa) |
| | RCVRN | Recoverin. (202 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2172 aa) |
| | EPHX2 | Epoxide hydrolase 2. (530 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (821 aa) |
| | STAT3 | Signal transducer and activator of transcription. (796 aa) |
| | FIS1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (582 aa) |
| | LDLR | Low density lipoprotein receptor. (902 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1111 aa) |
| | PLA2G3 | Phospholipase A2 group III. (506 aa) |
| | TTC39B | Tetratricopeptide repeat domain 39B. (643 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (781 aa) |
| | ATCAY | ATCAY kinesin light chain interacting caytaxin. (338 aa) |
| | CLK2 | CDC like kinase 2; Belongs to the protein kinase superfamily. (500 aa) |
| | SCAP | SREBF chaperone. (1281 aa) |
| | PARK7 | DJ-1_PfpI domain-containing protein. (155 aa) |
| | SOX9 | SRY-box transcription factor 9. (505 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | SLC7A11 | Solute carrier family 7 member 11. (503 aa) |
| | MLXIPL | MLX interacting protein like. (856 aa) |
| | NR1H2 | Nuclear receptor subfamily 1 group H member 2. (459 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (540 aa) |
| | BMP6 | Bone morphogenetic protein 6. (509 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (797 aa) |
| | WDR5 | WD repeat domain 5. (334 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa) |
| | ENSPCOP00000027809 | C2H2-type domain-containing protein. (142 aa) |
| | P2RY1 | Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | MIDN | Midnolin. (465 aa) |
| | GUCA1B | Guanylate cyclase activator 1B. (201 aa) |
| | APOC2 | Apolipoprotein C2. (101 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (553 aa) |
| | ANTKMT | Adenine nucleotide translocase lysine methyltransferase. (235 aa) |
| | RUSC1 | RUN and SH3 domain containing 1. (903 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (813 aa) |
| | REST | Uncharacterized protein. (1018 aa) |
| | GHSR | Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (364 aa) |
| | ENSPCOP00000026551 | Bromo domain-containing protein. (84 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | ENSPCOP00000025841 | Uncharacterized protein; Belongs to the adenylate kinase family. (171 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) |
| | INSR | Insulin receptor. (1192 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2432 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa) |
| | GIP | Gastric inhibitory polypeptide. (150 aa) |
| | RD3 | Retinal degeneration 3, GUCY2D regulator. (195 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1031 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | SIRT7 | Sirtuin 7. (400 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | SERPINA12 | Serpin family A member 12; Belongs to the serpin family. (413 aa) |
| | ADM | Adrenomedullin. (182 aa) |
| | FMO4 | Dimethylaniline monooxygenase [N-oxide-forming]. (557 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1180 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (454 aa) |
| | ENSPCOP00000023392 | Uncharacterized protein. (157 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | FLCN | Folliculin. (579 aa) |
| | HDAC4 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (972 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (663 aa) |
| | RORA | RAR related orphan receptor A. (532 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1133 aa) |
| | TFF3 | Trefoil factor 3. (80 aa) |
| | SESN2 | Sestrin 2. (480 aa) |
| | DYRK2 | Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa) |
| | GUCA2B | Guanylate cyclase activator 2B. (112 aa) |
| | APOA5 | Apolipoprotein A5. (371 aa) |
| | PPARGC1A | PPARG coactivator 1 alpha. (809 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | DAB2 | DAB adaptor protein 2. (769 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | PDK3 | Protein-serine/threonine kinase. (352 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1288 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | BMP5 | Bone morphogenetic protein 5. (379 aa) |
| | FAM3A | Family with sequence similarity 3 member A. (238 aa) |
| | SOGA1 | Suppressor of glucose, autophagy associated 1. (1412 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (746 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | C1QTNF3 | C1q domain-containing protein. (319 aa) |
| | LEPR | Leptin receptor. (1055 aa) |
| | ACTN3 | Actinin alpha 3 (gene/pseudogene). (936 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | PID1 | Phosphotyrosine interaction domain containing 1. (248 aa) |
| | APP | Amyloid beta precursor protein. (772 aa) |
| | LCMT1 | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (289 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | BEND3 | BEN domain containing 3. (828 aa) |
| | JMJD8 | Jumonji domain containing 8. (280 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | PTPN2 | Tyrosine-protein phosphatase non-receptor type. (415 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (502 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (553 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (646 aa) |
| | ENSPCOP00000012342 | RING-type domain-containing protein. (80 aa) |
| | FOXO1 | Forkhead box O1. (656 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (224 aa) |
| | PPTC7 | Protein phosphatase; Belongs to the PP2C family. (304 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (244 aa) |
| | TTC39A | Tetratricopeptide repeat domain 39A. (581 aa) |
| | ENSPCOP00000013232 | Protein-serine/threonine kinase. (359 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1465 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (410 aa) |
| | FABP1 | FABP domain-containing protein. (69 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (826 aa) |
| | HPCA | Hippocalcin. (193 aa) |
| | LOC105825287 | DJ-1_PfpI domain-containing protein. (189 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (645 aa) |
| | ZNF692 | Zinc finger protein 692. (513 aa) |
| | NKX1-1 | NK1 homeobox 1. (410 aa) |
| | SLC22A13 | Solute carrier family 22 member 13. (551 aa) |
| | ENSPCOP00000004143 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (136 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (442 aa) |
| | CD244 | CD244 molecule. (359 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | FMO5 | Dimethylaniline monooxygenase [N-oxide-forming]. (526 aa) |
| | GUCA2A | Guanylate cyclase activator 2A. (115 aa) |
| | CLCN2 | Chloride channel protein. (902 aa) |
| | GCK | Phosphotransferase. (466 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa) |
| | NOS1 | Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (2486 aa) |
| | EP300 | E1A binding protein p300. (2424 aa) |
| | CD320 | CD320 molecule. (259 aa) |
| | APOB | Apolipoprotein B. (4538 aa) |
| | AVP | Arginine vasopressin. (116 aa) |
| | IGF1 | Insulin like growth factor 1. (208 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (486 aa) |
| | UGT1A1 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (533 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (230 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | FH | Uncharacterized protein. (508 aa) |
| | GPT | Glutamic--pyruvic transaminase. (496 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (534 aa) |
| | SRC | Tyrosine-protein kinase. (543 aa) |
| | ARL2 | ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa) |
| | GNMT | Glycine N-methyltransferase. (295 aa) |
| | SELENOS | Selenoprotein S. (187 aa) |
| | SLC2A6 | Solute carrier family 2 member 6; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa) |
| | DHCR7 | 7-dehydrocholesterol reductase. (475 aa) |
| | SEC14L2 | Uncharacterized protein. (403 aa) |
| | GFI1 | Growth factor independent 1 transcriptional repressor. (422 aa) |
| | SNAI1 | Snail family transcriptional repressor 1. (264 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (638 aa) |
| | SEC14L4 | SEC14 like lipid binding 4. (406 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | HTR2A | 5-hydroxytryptamine receptor 2A. (471 aa) |
| | PDZD3 | PDZ domain containing 3. (544 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (529 aa) |
| | PLEK | Pleckstrin. (350 aa) |
| | CRY1 | Cryptochrome circadian regulator 1. (550 aa) |
| | IGFBP4 | Insulin like growth factor binding protein 4. (258 aa) |
| | KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (835 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa) |
| | PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (471 aa) |
| | FAM3C | Family with sequence similarity 3 member C. (227 aa) |
| | DUSP12 | Dual specificity phosphatase 12. (277 aa) |
| | ENSPCOP00000015642 | DJ-1_PfpI domain-containing protein. (175 aa) |
| | CPT1A | Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (367 aa) |
| | FOXA2 | Forkhead box A2. (463 aa) |
| | SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa) |
| | ADCYAP1R1 | ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (524 aa) |
| | ARPP19 | cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (131 aa) |
| | SLC4A1 | Anion exchange protein. (917 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa) |
| | COX11 | Cytochrome c oxidase copper chaperone COX11. (276 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (677 aa) |
| | PANK2 | Pantothenate kinase 2. (551 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | TSPO | Translocator protein. (169 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | CEACAM1 | Uncharacterized protein. (523 aa) |
| | BCKDK | Protein-serine/threonine kinase. (412 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa) |
| | SPHK2 | Sphingosine kinase 2. (660 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (741 aa) |
| | ENSPCOP00000001369 | Uncharacterized protein. (1468 aa) |
| | ENSPCOP00000001518 | TAFH domain-containing protein. (268 aa) |
| | GIT1 | GIT ArfGAP 1. (752 aa) |
| | MID1IP1 | MID1 interacting protein 1. (184 aa) |
| | MST1 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (300 aa) |
| | SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) |
| | LACC1 | Uncharacterized protein. (380 aa) |
| | TYSND1 | Trypsin domain containing 1. (566 aa) |
| | SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (313 aa) |
| | RORC | RAR related orphan receptor C. (520 aa) |
| | SEC14L3 | SEC14 like lipid binding 3. (400 aa) |
| | SORBS1 | Sorbin and SH3 domain containing 1. (1294 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (272 aa) |
| | PROX1 | Prospero homeobox 1. (737 aa) |
| | PMAIP1 | Uncharacterized protein. (54 aa) |
| | ETFBKMT | Electron transfer flavoprotein subunit beta lysine methyltransferase. (261 aa) |
| | PHKG2 | Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) |
| | ERLIN1 | ER lipid raft associated 1. (348 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | PDK1 | Protein-serine/threonine kinase. (438 aa) |
| | DGKQ | Diacylglycerol kinase. (939 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (498 aa) |
| | C1QTNF1 | C1q and TNF related 1. (281 aa) |
| | ENSPCOP00000006746 | Uncharacterized protein. (188 aa) |
| | ATPSCKMT | ATP synthase c subunit lysine N-methyltransferase. (233 aa) |
| | FABP3 | Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa) |
| | PLIN5 | Perilipin; Belongs to the perilipin family. (450 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (348 aa) |
| | FABP5 | Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | HPCAL1 | Hippocalcin like 1. (199 aa) |
| | PGP | Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (321 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (291 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1142 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (327 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (961 aa) |
| | C1QTNF6 | C1q and TNF related 6. (263 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (675 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (402 aa) |
| | ENSPCOP00000008878 | Uncharacterized protein. (329 aa) |
| | PDK4 | Protein-serine/threonine kinase. (412 aa) |
| | SLC7A7 | Solute carrier family 7 member 7. (511 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (261 aa) |
| | ERLIN2 | ER lipid raft associated 2. (323 aa) |
| | ERFE | Erythroferrone. (340 aa) |
| | ENSPCOP00000009443 | Uncharacterized protein. (69 aa) |
| | PGAM1 | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa) |
| | CD74 | CD74 molecule. (298 aa) |
| | GUCA1C | Guanylate cyclase activator 1C. (210 aa) |
| | NOS3 | Nitric oxide synthase 3. (994 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1281 aa) |
| | STARD4 | StAR related lipid transfer domain containing 4. (205 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | GCG | Glucagon. (180 aa) |
| | APOE | Apolipoprotein E. (314 aa) |
| | GCKR | Glucokinase regulator. (575 aa) |
| | SLC4A4 | Anion exchange protein. (884 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (591 aa) |
| | CLN3 | Battenin. (438 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
