STRINGSTRING
GAR1 GAR1 DKC1 DKC1 NOP10 NOP10 ENSPCOP00000030829 ENSPCOP00000030829 LOC105815151 LOC105815151 TEP1 TEP1 ENSPCOP00000025432 ENSPCOP00000025432 HNRNPC HNRNPC DCP2 DCP2 LOC105820095 LOC105820095 SMG5 SMG5 SMG6 SMG6 WRAP53 WRAP53 TENT4B TENT4B HNRNPU HNRNPU NHP2 NHP2 ENSPCOP00000002776 ENSPCOP00000002776 DHX36 DHX36 SNRPD3 SNRPD3 SMG7 SMG7 XRN1 XRN1 SNRPB SNRPB EXOSC10 EXOSC10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAR1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (196 aa)
DKC1Dyskerin pseudouridine synthase 1. (514 aa)
NOP10NOP10 ribonucleoprotein. (64 aa)
ENSPCOP00000030829G-patch domain-containing protein. (169 aa)
LOC105815151Uncharacterized protein. (913 aa)
TEP1Telomerase associated protein 1. (2562 aa)
ENSPCOP00000025432Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
HNRNPCHeterogeneous nuclear ribonucleoprotein C (C1/C2). (322 aa)
DCP2Decapping mRNA 2. (423 aa)
LOC105820095Uncharacterized protein. (784 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (1016 aa)
SMG6SMG6 nonsense mediated mRNA decay factor. (1419 aa)
WRAP53WD repeat containing antisense to TP53. (540 aa)
TENT4BTerminal nucleotidyltransferase 4B. (607 aa)
HNRNPUUncharacterized protein. (824 aa)
NHP2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (153 aa)
ENSPCOP00000002776Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
DHX36HA2 domain-containing protein. (718 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
SMG7SMG7 nonsense mediated mRNA decay factor. (1177 aa)
XRN15'-3' exoribonuclease 1. (1706 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
EXOSC10Exosome component 10. (878 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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