STRINGSTRING
NDRG4 NDRG4 GAREM2 GAREM2 LOC105813852 LOC105813852 FERMT2 FERMT2 TREM2 TREM2 MTURN MTURN APELA APELA FGF8 FGF8 CCN2 CCN2 NRXN1 NRXN1 SCIMP SCIMP DDR2 DDR2 ENSPCOP00000019705 ENSPCOP00000019705 FBXW7 FBXW7 RAPGEF2 RAPGEF2 FSHR FSHR SLAMF1 SLAMF1 CX3CL1 CX3CL1 CCL22 CCL22 ANGPT1 ANGPT1 LOC105821125 LOC105821125 CCL14 CCL14 HCRTR1 HCRTR1 SERPINF2 SERPINF2 GCNT2 GCNT2 ALKAL2 ALKAL2 AGER AGER GAS6 GAS6 CCL21 CCL21 ENSPCOP00000000202 ENSPCOP00000000202 FGF10 FGF10 CCL8 CCL8 ACKR3 ACKR3 PHB PHB PRKCZ PRKCZ PTEN PTEN LOC105822640 LOC105822640 RAP1A RAP1A HAND2 HAND2 MAP2K7 MAP2K7 CCL5 CCL5 NOTCH2 NOTCH2 PDGFB PDGFB CCL24 CCL24 MT3 MT3 CAVIN3 CAVIN3 ADCYAP1 ADCYAP1 CXCL17 CXCL17 DENND2B DENND2B NOTCH1 NOTCH1 FGF23 FGF23 KDR KDR HAVCR2 HAVCR2 LOC105824853 LOC105824853 HTR2A HTR2A ALOX15 ALOX15 CIB1 CIB1 FGB FGB GAREM1 GAREM1 CCL20 CCL20 TNFAIP8L3 TNFAIP8L3 CCL16 CCL16 DDT DDT MAPK3 MAPK3 TNFRSF11A TNFRSF11A VEGFB VEGFB TEK TEK PDGFC PDGFC RASGRP1 RASGRP1 NRG1 NRG1 PTPN22 PTPN22 CD4 CD4 CD74 CD74 ENSPCOP00000009588 ENSPCOP00000009588 CASR CASR FLT4 FLT4 NODAL NODAL GCG GCG APOE APOE CCR7 CCR7 LOC105824854 LOC105824854 FGF1 FGF1 CD36 CD36 NTRK1 NTRK1 AKAP12 AKAP12 CHI3L1 CHI3L1 APP APP CCL26 CCL26 IGF1 IGF1 MIF MIF ARHGAP8 ARHGAP8 TGFB1 TGFB1 TIRAP TIRAP FFAR4 FFAR4 IL26 IL26 ALKAL1 ALKAL1 ADRA1A ADRA1A ABL1 ABL1 CARD9 CARD9 FGF18 FGF18 PLA2G5 PLA2G5 SHC1 SHC1 LOC105819920 LOC105819920 RAMP3 RAMP3 NOD1 NOD1 PYCARD PYCARD TNFSF11 TNFSF11 FGF20 FGF20 FGF4 FGF4 FGF2 FGF2 BMP2 BMP2 TRPV4 TRPV4 PDGFRB PDGFRB FGFR2 FGFR2 HTR2B HTR2B CRKL CRKL CCL1 CCL1 PRKCA PRKCA PTPN11 PTPN11 ENSPCOP00000029403 ENSPCOP00000029403 MAP3K12 MAP3K12 NOD2 NOD2 FGF21 FGF21 NPY5R NPY5R FGFR4 FGFR4 BMP4 BMP4 LOC105811462 LOC105811462 ABCA7 ABCA7 CCL4 CCL4 FGFR3 FGFR3 PTK2B PTK2B GATA4 GATA4 P2RY1 P2RY1 LOC105822688 LOC105822688 SPRY2 SPRY2 CD44 CD44 ENSPCOP00000026834 ENSPCOP00000026834 DNAJC27 DNAJC27 CSF1R CSF1R ENSPCOP00000026475 ENSPCOP00000026475 NELFE NELFE GLIPR2 GLIPR2 PDGFA PDGFA RIPK2 RIPK2 BRAF BRAF FBXW9 FBXW9 VEGFA VEGFA BMPER BMPER CCL19 CCL19 FGA FGA CALCR CALCR FGG FGG MFHAS1 MFHAS1 CCL23 CCL23 PRKD2 PRKD2 NECAB2 NECAB2 SLC30A10 SLC30A10 OPRM1 OPRM1 CCL17 CCL17 GPNMB GPNMB CCL25 CCL25 LOC105810447 LOC105810447 DSTYK DSTYK MAP2K1 MAP2K1 NPTN NPTN NRP1 NRP1 FGF19 FGF19 LOC105827044 LOC105827044 CCL13 CCL13 ENSPCOP00000017622 ENSPCOP00000017622 ICAM1 ICAM1 SEMA7A SEMA7A EGFR EGFR SRC SRC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NDRG4NDRG family member 4. (391 aa)
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (875 aa)
LOC105813852C-C motif chemokine. (94 aa)
FERMT2Fermitin family member 2. (693 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
MTURNMaturin, neural progenitor differentiation regulator homolog. (131 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
CCN2Cellular communication network factor 2. (347 aa)
NRXN1Neurexin 1. (1449 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (141 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
ENSPCOP00000019705Uncharacterized protein. (583 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1658 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (368 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (405 aa)
CCL22C-C motif chemokine. (93 aa)
ANGPT1Angiopoietin 1. (408 aa)
LOC105821125SCY domain-containing protein. (114 aa)
CCL14C-C motif chemokine. (95 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (424 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (487 aa)
GCNT2Glucosaminyl (N-acetyl) transferase 2 (I blood group). (329 aa)
ALKAL2Uncharacterized protein. (91 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
GAS6Growth arrest specific 6. (648 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
ENSPCOP00000000202Prohibitin. (262 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CCL8C-C motif chemokine. (99 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PHBProhibitin. (272 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LOC105822640Integrin beta; Belongs to the integrin beta chain family. (454 aa)
RAP1ARAP1A, member of RAS oncogene family. (165 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (435 aa)
CCL5C-C motif chemokine. (91 aa)
NOTCH2Notch receptor 2. (2471 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (114 aa)
CAVIN3Caveolae associated protein 3. (286 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
DENND2BSuppression of tumorigenicity 5. (1137 aa)
NOTCH1Notch receptor 1. (2420 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (272 aa)
LOC105824853Uncharacterized protein. (401 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
CIB1Calcium and integrin binding 1. (191 aa)
FGBFibrinogen beta chain. (492 aa)
GAREM1GRB2 associated regulator of MAPK1 subtype 1. (876 aa)
CCL20C-C motif chemokine. (96 aa)
TNFAIP8L3TNF alpha induced protein 8 like 3. (285 aa)
CCL16C-C motif chemokine. (118 aa)
DDTUncharacterized protein. (136 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
TNFRSF11ATNF receptor superfamily member 11a. (584 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (284 aa)
RASGRP1RAS guanyl releasing protein 1. (827 aa)
NRG1Neuregulin 1. (710 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (653 aa)
CD4CD4 molecule. (452 aa)
CD74CD74 molecule. (298 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
CASRCalcium sensing receptor. (1076 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
NODALNodal growth differentiation factor. (348 aa)
GCGGlucagon. (180 aa)
APOEApolipoprotein E. (314 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC105824854Uncharacterized protein. (312 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
AKAP12A-kinase anchoring protein 12. (1773 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (385 aa)
APPAmyloid beta precursor protein. (772 aa)
CCL26C-C motif chemokine. (92 aa)
IGF1Insulin like growth factor 1. (208 aa)
MIFUncharacterized protein. (115 aa)
ARHGAP8Uncharacterized protein. (443 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
TIRAPTIR domain containing adaptor protein. (198 aa)
FFAR4Free fatty acid receptor 4. (361 aa)
IL26Interleukin 26. (171 aa)
ALKAL1ALK and LTK ligand 1. (131 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
ABL1Tyrosine-protein kinase. (1146 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PLA2G5Phospholipase A(2). (138 aa)
SHC1SHC adaptor protein 1. (582 aa)
LOC105819920Uncharacterized protein. (116 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (949 aa)
PYCARDPYD and CARD domain containing. (195 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (320 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (394 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1105 aa)
FGFR2Fibroblast growth factor receptor. (797 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CCL1C-C motif chemokine ligand 1. (96 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSPCOP00000029403Protein kinase domain-containing protein. (429 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (891 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
NPY5RNeuropeptide Y receptor Y5. (446 aa)
FGFR4Fibroblast growth factor receptor. (797 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
LOC105811462Olfactory receptor. (321 aa)
ABCA7ATP binding cassette subfamily A member 7. (2015 aa)
CCL4C-C motif chemokine. (92 aa)
FGFR3Fibroblast growth factor receptor. (807 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (967 aa)
GATA4GATA binding protein 4. (445 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
LOC105822688Uncharacterized protein. (54 aa)
SPRY2Sprouty RTK signaling antagonist 2. (314 aa)
CD44CD44 molecule (Indian blood group). (746 aa)
ENSPCOP00000026834Uncharacterized protein. (276 aa)
DNAJC27DnaJ heat shock protein family (Hsp40) member C27. (273 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
ENSPCOP00000026475PDEase domain-containing protein. (163 aa)
NELFENegative elongation factor complex member E. (385 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (745 aa)
FBXW9F-box and WD repeat domain containing 9. (478 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
BMPERBMP binding endothelial regulator. (704 aa)
CCL19C-C motif chemokine. (108 aa)
FGAFib_alpha domain-containing protein. (649 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (479 aa)
FGGFibrinogen gamma chain. (456 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1037 aa)
CCL23C-C motif chemokine. (119 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
NECAB2N-terminal EF-hand calcium binding protein 2. (319 aa)
SLC30A10Solute carrier family 30 member 10. (486 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (479 aa)
CCL17C-C motif chemokine. (102 aa)
GPNMBGlycoprotein nmb. (567 aa)
CCL25SCY domain-containing protein. (109 aa)
LOC105810447Uncharacterized protein. (119 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (928 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (377 aa)
NPTNUncharacterized protein. (399 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
LOC105827044Phosphodiesterase 8A; Belongs to the cyclic nucleotide phosphodiesterase family. (748 aa)
CCL13C-C motif chemokine. (98 aa)
ENSPCOP00000017622Uncharacterized protein. (122 aa)
ICAM1Intercellular adhesion molecule 1. (533 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
SRCTyrosine-protein kinase. (543 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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