95 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EGF	Epidermal growth factor. (1132 aa)
	TRPM4	Transient receptor potential cation channel subfamily M member 4. (1204 aa)
	SOX4	Transcription factor SOX. (479 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)
	ENSPCOP00000000851	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (124 aa)
	USP47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1376 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	WNK1	WNK lysine deficient protein kinase 1. (2808 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	PPM1B	PPM-type phosphatase domain-containing protein. (387 aa)
	GPC3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
	HHEX	Hematopoietically expressed homeobox. (271 aa)
	ENSPCOP00000004829	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (71 aa)
	ENSPCOP00000004928	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (258 aa)
	TTC21B	Tetratricopeptide repeat domain 21B. (1163 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (391 aa)
	ASPM	Abnormal spindle microtubule assembly. (3472 aa)
	LRRK1	Leucine rich repeat kinase 1. (2012 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (958 aa)
	UBR5	Ubiquitin protein ligase E3 component n-recognin 5. (2776 aa)
	RSPO1	R-spondin 1. (266 aa)
	ENSPCOP00000007374	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (152 aa)
	ENSPCOP00000007435	DUF4203 domain-containing protein. (348 aa)
	TMEM198	Transmembrane protein 198. (360 aa)
	CTDNEP1	CTD nuclear envelope phosphatase 1. (244 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (961 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
	LOC105805276	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
	KANK1	KN motif and ankyrin repeat domains 1. (1350 aa)
	XIAP	X-linked inhibitor of apoptosis. (497 aa)
	SMURF2	SMAD specific E3 ubiquitin protein ligase 2. (602 aa)
	NLE1	Notchless homolog 1. (485 aa)
	DKK2	Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
	TMEM9	Transmembrane protein 9. (183 aa)
	YAP1	Uncharacterized protein. (504 aa)
	VPS35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
	PRDM15	PR/SET domain 15. (1183 aa)
	PIN1	Peptidyl-prolyl cis-trans isomerase. (163 aa)
	JUP	Junction plakoglobin. (745 aa)
	DAAM2	Dishevelled associated activator of morphogenesis 2. (1077 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1072 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	RSPO2	R-spondin 2. (243 aa)
	RUVBL1	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (245 aa)
	ADGRA2	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1314 aa)
	USP34	Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3561 aa)
	GID8	GID complex subunit 8 homolog. (228 aa)
	AMER1	APC membrane recruitment protein 1. (796 aa)
	RECK	Reversion inducing cysteine rich protein with kazal motifs. (969 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ENSPCOP00000016901	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (126 aa)
	SFRP4	Secreted frizzled related protein 4. (342 aa)
	EGFR	Receptor protein-tyrosine kinase. (1210 aa)
	SCEL	Sciellin. (630 aa)
	SRC	Tyrosine-protein kinase. (543 aa)
	SFRP2	Secreted frizzled related protein 2. (295 aa)
	PPM1N	Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (422 aa)
	COL1A1	Collagen type I alpha 1 chain. (1461 aa)
	ZEB2	Zinc finger E-box binding homeobox 2. (1258 aa)
	ATP6AP2	ATPase H+ transporting accessory protein 2. (273 aa)
	SMAD3	Mothers against decapentaplegic homolog. (443 aa)
	CCAR2	Cell cycle and apoptosis regulator 2. (922 aa)
	ARNTL	Aryl hydrocarbon receptor nuclear translocator like. (626 aa)
	DAPK3	Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
	GPRC5B	G protein-coupled receptor class C group 5 member B. (404 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	WLS	Wnt ligand secretion mediator. (543 aa)
	CAPRIN2	Caprin family member 2. (1069 aa)
	LYPD6	LY6/PLAUR domain containing 6. (171 aa)
	TNKS2	Poly [ADP-ribose] polymerase. (1018 aa)
	LRRK2	Leucine rich repeat kinase 2. (2427 aa)
	ENSPCOP00000025005	Uncharacterized protein. (351 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	DLX5	Distal-less homeobox 5. (289 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	WNK2	WNK lysine deficient protein kinase 2. (2211 aa)
	CDH3	Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (825 aa)
	PLEKHA4	Pleckstrin homology domain containing A4. (777 aa)
	ENSPCOP00000026845	USP8_dimer domain-containing protein. (167 aa)
	JRK	Jrk helix-turn-helix protein. (550 aa)
	RNF220	Ring finger protein 220. (566 aa)
	RNF146	Ring finger protein 146. (358 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1068 aa)
	ENSPCOP00000030206	Ribosomal_L7Ae domain-containing protein. (124 aa)
	FGFR2	Fibroblast growth factor receptor. (797 aa)
	LGR4	Leucine rich repeat containing G protein-coupled receptor 4. (920 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	FAM53B	Family with sequence similarity 53 member B. (424 aa)
	GSKIP	GSK3B interacting protein. (139 aa)
	BAMBI	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
	LOC105807749	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (284 aa)
	DACT1	Dishevelled binding antagonist of beta catenin 1. (798 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRA2	EGFR	ENSPCOP00000015176	ENSPCOP00000018322	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Receptor protein-tyrosine kinase.	0.433
ADGRA2	LRRK2	ENSPCOP00000015176	ENSPCOP00000024566	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat kinase 2.	0.537
ADGRA2	PTK7	ENSPCOP00000015176	ENSPCOP00000012721	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.548
ADGRA2	RECK	ENSPCOP00000015176	ENSPCOP00000016713	Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family.	Reversion inducing cysteine rich protein with kazal motifs.	0.632
AMER1	JUP	ENSPCOP00000016441	ENSPCOP00000012399	APC membrane recruitment protein 1.	Junction plakoglobin.	0.893
AMER1	WNT3A	ENSPCOP00000016441	ENSPCOP00000025417	APC membrane recruitment protein 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.582
ARNTL	BAMBI	ENSPCOP00000022267	ENSPCOP00000031339	Aryl hydrocarbon receptor nuclear translocator like.	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	0.429
ARNTL	LOC105805276	ENSPCOP00000022267	ENSPCOP00000009537	Aryl hydrocarbon receptor nuclear translocator like.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.990
ARNTL	TBL1XR1	ENSPCOP00000022267	ENSPCOP00000025097	Aryl hydrocarbon receptor nuclear translocator like.	Transducin beta like 1 X-linked receptor 1.	0.478
ASPM	TRPM4	ENSPCOP00000005663	ENSPCOP00000000162	Abnormal spindle microtubule assembly.	Transient receptor potential cation channel subfamily M member 4.	0.450
BAMBI	ARNTL	ENSPCOP00000031339	ENSPCOP00000022267	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Aryl hydrocarbon receptor nuclear translocator like.	0.429
BAMBI	EGF	ENSPCOP00000031339	ENSPCOP00000014650	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Epidermal growth factor.	0.453
BAMBI	SFRP1	ENSPCOP00000031339	ENSPCOP00000030622	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Secreted frizzled related protein 1.	0.581
BAMBI	SFRP2	ENSPCOP00000031339	ENSPCOP00000018912	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Secreted frizzled related protein 2.	0.596
BAMBI	SFRP4	ENSPCOP00000031339	ENSPCOP00000017722	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Secreted frizzled related protein 4.	0.566
BAMBI	SMAD3	ENSPCOP00000031339	ENSPCOP00000021905	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Mothers against decapentaplegic homolog.	0.662
BAMBI	TGFB1	ENSPCOP00000031339	ENSPCOP00000023065	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.772
CAV1	EGF	ENSPCOP00000025045	ENSPCOP00000014650	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Epidermal growth factor.	0.599
CAV1	EGFR	ENSPCOP00000025045	ENSPCOP00000018322	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Receptor protein-tyrosine kinase.	0.951
CAV1	JUP	ENSPCOP00000025045	ENSPCOP00000012399	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin.	0.657