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FGG FGG TRPM4 TRPM4 GCLM GCLM SERPINF2 SERPINF2 PRKG1 PRKG1 ECE1 ECE1 ATP2B1 ATP2B1 GCH1 GCH1 ADORA2A ADORA2A ADCY6 ADCY6 AVPR2 AVPR2 HTR1D HTR1D KNG1 KNG1 ENSPCOP00000004143 ENSPCOP00000004143 DOCK4 DOCK4 DRD5 DRD5 ITGA1 ITGA1 AVPR1A AVPR1A KEL KEL CRP CRP CHRM4 CHRM4 HRH2 HRH2 VSTM4 VSTM4 HTR1B HTR1B EDN1 EDN1 GUCY1A1 GUCY1A1 FGB FGB BDKRB2 BDKRB2 PLA2G6 PLA2G6 ROCK1 ROCK1 MMP2 MMP2 UTS2B UTS2B ATG5 ATG5 ZDHHC21 ZDHHC21 TBXA2R TBXA2R GRIP2 GRIP2 PTGS2 PTGS2 CASR CASR DOCK5 DOCK5 NOS3 NOS3 UTS2 UTS2 APOE APOE ADRA1B ADRA1B NPR1 NPR1 ROCK2 ROCK2 RGS2 RGS2 EDN2 EDN2 TACR1 TACR1 SLC8A1 SLC8A1 SCNN1B SCNN1B ADRB3 ADRB3 EDNRB EDNRB P2RX1 P2RX1 BMPR2 BMPR2 KCNMB4 KCNMB4 SOD1 SOD1 GCLC GCLC SMTNL2 SMTNL2 MKKS MKKS AVPR1B AVPR1B EXT2 EXT2 KCNMB1 KCNMB1 KCNMB2 KCNMB2 EXT1 EXT1 AVP AVP ADRA2C ADRA2C BBS2 BBS2 NOS1 NOS1 AGTR1 AGTR1 CPS1 CPS1 HTR7 HTR7 NPR3 NPR3 COMP COMP DBH DBH ADRA1D ADRA1D ENSPCOP00000022475 ENSPCOP00000022475 ITGB1BP1 ITGB1BP1 ARHGAP42 ARHGAP42 FGA FGA VEGFA VEGFA ADM ADM CAV1 CAV1 KLF2 KLF2 KCNMA1 KCNMA1 SMTNL1 SMTNL1 ADORA2B ADORA2B RAP1GDS1 RAP1GDS1 EDN3 EDN3 FOXC2 FOXC2 ASIC2 ASIC2 DRD1 DRD1 AGTR2 AGTR2 SCPEP1 SCPEP1 P2RY1 P2RY1 FOXC1 FOXC1 AGT AGT NPPB NPPB SNTA1 SNTA1 EDNRA EDNRA HTR2B HTR2B PPARD PPARD ENSPCOP00000030811 ENSPCOP00000030811 PER2 PER2 NPPA NPPA OXTR OXTR ADRA1A ADRA1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGGFibrinogen gamma chain. (456 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (487 aa)
PRKG1Protein kinase cGMP-dependent 1. (593 aa)
ECE1Endothelin converting enzyme 1. (758 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
GCH1GTP cyclohydrolase 1. (250 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (411 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1167 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (371 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
KNG1Uncharacterized protein. (391 aa)
ENSPCOP00000004143Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (136 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (1966 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (434 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1025 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (410 aa)
KELKell metallo-endopeptidase (Kell blood group). (730 aa)
CRPPentaxin. (225 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (422 aa)
VSTM4V-set and transmembrane domain containing 4. (309 aa)
HTR1B5-hydroxytryptamine receptor 1B. (390 aa)
EDN1Endothelin 1. (193 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
FGBFibrinogen beta chain. (492 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (393 aa)
PLA2G6Phospholipase A2 group VI. (807 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
MMP2Matrix metallopeptidase 2. (552 aa)
UTS2BUrotensin 2B. (119 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (247 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
GRIP2Glutamate receptor interacting protein 2. (961 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
CASRCalcium sensing receptor. (1076 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1723 aa)
NOS3Nitric oxide synthase 3. (994 aa)
UTS2Urotensin 2. (126 aa)
APOEApolipoprotein E. (314 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
NPR1Guanylate cyclase. (1058 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
EDN2Endothelin 2. (178 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (663 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (405 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (485 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1037 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (153 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (637 aa)
SMTNL2Smoothelin like 2. (457 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (539 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
AVPArginine vasopressin. (116 aa)
ADRA2CAdrenoceptor alpha 2C; Belongs to the G-protein coupled receptor 1 family. (351 aa)
BBS2Bardet-Biedl syndrome 2. (614 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (388 aa)
CPS1Carbamoyl-phosphate synthase 1. (1310 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (465 aa)
NPR3Natriuretic peptide receptor 3. (539 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
DBHDopamine beta-hydroxylase. (620 aa)
ADRA1DAdrenoceptor alpha 1D. (577 aa)
ENSPCOP00000022475Uncharacterized protein. (173 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
ARHGAP42Rho GTPase activating protein 42. (852 aa)
FGAFib_alpha domain-containing protein. (649 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
ADMAdrenomedullin. (182 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
KLF2Kruppel like factor 2. (356 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
SMTNL1Smoothelin like 1. (447 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
RAP1GDS1Rap1 GTPase-GDP dissociation stimulator 1. (521 aa)
EDN3Endothelin 3. (224 aa)
FOXC2Forkhead box C2. (503 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (563 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (412 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
FOXC1Forkhead box C1. (535 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
NPPBNatriuretic peptide B. (132 aa)
SNTA1Syntrophin alpha 1. (505 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
PPARDPeroxisome proliferator activated receptor delta. (440 aa)
ENSPCOP00000030811Sod_Cu domain-containing protein. (132 aa)
PER2Period circadian regulator 2. (1265 aa)
NPPANatriuretic peptide A. (153 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (388 aa)
ADRA1AAdrenoceptor alpha 1A. (466 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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