(58 nodes) Cell-cell adhesion mediator activity network (Propithecus coquereli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRT18	IF rod domain-containing protein; Belongs to the intermediate filament family. (431 aa)
	ENSPCOP00000000109	Protein S100; Belongs to the S-100 family. (101 aa)
	CCDC141	Coiled-coil domain containing 141. (956 aa)
	PKP2	Plakophilin 2. (838 aa)
	ENSPCOP00000001609	Ig-like domain-containing protein. (159 aa)
	ENSPCOP00000001901	Ig-like domain-containing protein. (127 aa)
	STXBP6	Syntaxin binding protein 6. (210 aa)
	ROBO4	Uncharacterized protein. (970 aa)
	PAK4	Non-specific serine/threonine protein kinase. (588 aa)
	S100A11	Protein S100; Belongs to the S-100 family. (105 aa)
	PKP3	Plakophilin 3. (796 aa)
	DSP	Desmoplakin. (2868 aa)
	NINJ1	Ninjurin 1. (152 aa)
	IGSF9	Immunoglobulin superfamily member 9. (1179 aa)
	VSIG2	V-set and immunoglobulin domain containing 2. (327 aa)
	SIRPA	Uncharacterized protein. (500 aa)
	ENSPCOP00000009674	Uncharacterized protein. (606 aa)
	ENSPCOP00000009764	Ig-like domain-containing protein. (130 aa)
	CNTN3	Contactin 3. (1022 aa)
	LOC105821460	Uncharacterized protein. (516 aa)
	NFASC	Neurofascin. (1237 aa)
	EPCAM	Thyroglobulin type-1 domain-containing protein. (335 aa)
	DSCAM	DS cell adhesion molecule. (1917 aa)
	BSG	Basigin (Ok blood group). (385 aa)
	PALLD	Palladin, cytoskeletal associated protein. (777 aa)
	JUP	Junction plakoglobin. (745 aa)
	NEXN	Nexilin F-actin binding protein. (675 aa)
	ROBO2	Roundabout guidance receptor 2. (1323 aa)
	CDC42EP1	CDC42 effector protein 1. (362 aa)
	IZUMO1	Izumo sperm-egg fusion 1. (349 aa)
	NRCAM	Neuronal cell adhesion molecule. (1304 aa)
	CD200	CD200 molecule. (269 aa)
	CNTN1	Contactin 1. (1018 aa)
	NPTN	Uncharacterized protein. (399 aa)
	CNN3	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (329 aa)
	ENSPCOP00000017622	Uncharacterized protein. (122 aa)
	DSCAML1	DS cell adhesion molecule like 1. (1882 aa)
	PDLIM5	PDZ and LIM domain 5. (568 aa)
	LOC105826440	IF rod domain-containing protein; Belongs to the intermediate filament family. (419 aa)
	JAM3	Junctional adhesion molecule 3. (310 aa)
	ENSPCOP00000019747	Uncharacterized protein. (330 aa)
	ESAM	Endothelial cell adhesion molecule. (391 aa)
	ROBO3	Roundabout guidance receptor 3. (1385 aa)
	ENSPCOP00000020151	EpCAM_N domain-containing protein. (283 aa)
	BAIAP2L1	BAI1 associated protein 2 like 1. (510 aa)
	BAIAP2	BAI1 associated protein 2. (544 aa)
	CNTN4	Contactin 4. (1010 aa)
	GLDN	Gliomedin. (550 aa)
	CNTN2	Contactin 2. (1040 aa)
	DSG2	Desmoglein 2. (1029 aa)
	PDLIM1	PDZ and LIM domain 1. (329 aa)
	PLXNB3	Plexin B3. (1936 aa)
	VSTM2L	V-set and transmembrane domain containing 2 like. (204 aa)
	NTNG1	Netrin G1. (542 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	TMOD3	Tropomodulin 3. (352 aa)
	MYPN	Myopalladin. (1287 aa)
	CD200R1	Ig-like domain-containing protein. (324 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAIAP2	BAIAP2L1	ENSPCOP00000021435	ENSPCOP00000021206	BAI1 associated protein 2.	BAI1 associated protein 2 like 1.	0.967
BAIAP2	PAK4	ENSPCOP00000021435	ENSPCOP00000006025	BAI1 associated protein 2.	Non-specific serine/threonine protein kinase.	0.515
BAIAP2	PDLIM1	ENSPCOP00000021435	ENSPCOP00000024266	BAI1 associated protein 2.	PDZ and LIM domain 1.	0.425
BAIAP2L1	BAIAP2	ENSPCOP00000021206	ENSPCOP00000021435	BAI1 associated protein 2 like 1.	BAI1 associated protein 2.	0.967
BAIAP2L1	DSG2	ENSPCOP00000021206	ENSPCOP00000022544	BAI1 associated protein 2 like 1.	Desmoglein 2.	0.509
BAIAP2L1	PAK4	ENSPCOP00000021206	ENSPCOP00000006025	BAI1 associated protein 2 like 1.	Non-specific serine/threonine protein kinase.	0.487
BSG	EPCAM	ENSPCOP00000012247	ENSPCOP00000011227	Basigin (Ok blood group).	Thyroglobulin type-1 domain-containing protein.	0.425
BSG	NTNG1	ENSPCOP00000012247	ENSPCOP00000027036	Basigin (Ok blood group).	Netrin G1.	0.484
CCDC141	PAK4	ENSPCOP00000000605	ENSPCOP00000006025	Coiled-coil domain containing 141.	Non-specific serine/threonine protein kinase.	0.464
CD200	CD200R1	ENSPCOP00000015794	ENSPCOP00000030420	CD200 molecule.	Ig-like domain-containing protein.	0.831
CD200R1	CD200	ENSPCOP00000030420	ENSPCOP00000015794	Ig-like domain-containing protein.	CD200 molecule.	0.831
CDC42EP1	STXBP6	ENSPCOP00000013403	ENSPCOP00000002434	CDC42 effector protein 1.	Syntaxin binding protein 6.	0.448
CNN3	DSP	ENSPCOP00000017454	ENSPCOP00000008154	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Desmoplakin.	0.463
CNTN1	GLDN	ENSPCOP00000015893	ENSPCOP00000022074	Contactin 1.	Gliomedin.	0.408
CNTN1	NFASC	ENSPCOP00000015893	ENSPCOP00000010767	Contactin 1.	Neurofascin.	0.993
CNTN1	NRCAM	ENSPCOP00000015893	ENSPCOP00000014710	Contactin 1.	Neuronal cell adhesion molecule.	0.951
CNTN2	NFASC	ENSPCOP00000022084	ENSPCOP00000010767	Contactin 2.	Neurofascin.	0.911
CNTN2	NRCAM	ENSPCOP00000022084	ENSPCOP00000014710	Contactin 2.	Neuronal cell adhesion molecule.	0.948
CNTN3	NFASC	ENSPCOP00000009847	ENSPCOP00000010767	Contactin 3.	Neurofascin.	0.832
CNTN3	NRCAM	ENSPCOP00000009847	ENSPCOP00000014710	Contactin 3.	Neuronal cell adhesion molecule.	0.831