STRINGSTRING
RYR2 RYR2 ENSPCOP00000009091 ENSPCOP00000009091 TBX18 TBX18 DSP DSP TMEM161B TMEM161B HCN4 HCN4 CAV3 CAV3 PKP2 PKP2 TRPM4 TRPM4 CAMK2D CAMK2D CTNNA3 CTNNA3 ANK2 ANK2 DSG2 DSG2 RANGRF RANGRF CAV1 CAV1 CACNA1C CACNA1C HCN2 HCN2 HCN3 HCN3 AKAP9 AKAP9 DLG1 DLG1 ATP2A2 ATP2A2 JUP JUP BIN1 BIN1 NOS1AP NOS1AP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYR2Ryanodine receptor 2. (4825 aa)
ENSPCOP00000009091Uncharacterized protein. (291 aa)
TBX18T-box transcription factor 18. (607 aa)
DSPDesmoplakin. (2868 aa)
TMEM161BTransmembrane protein 161B. (471 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1199 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PKP2Plakophilin 2. (838 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (503 aa)
CTNNA3Catenin alpha 3. (783 aa)
ANK2Ankyrin 2. (3925 aa)
DSG2Desmoglein 2. (1029 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (816 aa)
HCN3Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (779 aa)
AKAP9A-kinase anchoring protein 9. (3687 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (910 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
JUPJunction plakoglobin. (745 aa)
BIN1Bridging integrator 1. (594 aa)
NOS1APNitric oxide synthase 1 adaptor protein. (507 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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