STRINGSTRING
ENSPCOP00000031789 ENSPCOP00000031789 WNT2 WNT2 SOX9 SOX9 BMP4 BMP4 SPRY1 SPRY1 SIX4 SIX4 TGFB1 TGFB1 CTNNB1 CTNNB1 GDNF GDNF SOX8 SOX8 WNT4 WNT4 DKK1 DKK1 FRS2 FRS2 HOXA11 HOXA11 NGFR NGFR STOX1 STOX1 FGF8 FGF8 FGF1 FGF1 SIX1 SIX1 GATA3 GATA3 WNT5A WNT5A HOXC11 HOXC11 CSF1 CSF1 WNT11 WNT11 FGF10 FGF10 WNT2B WNT2B MESP1 MESP1 AR AR BMP2 BMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000031789Uncharacterized protein. (227 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SOX9SRY-box transcription factor 9. (505 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SIX4SIX homeobox 4. (782 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CTNNB1Catenin beta 1. (781 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
SOX8SRY-box transcription factor 8. (462 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (268 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
HOXA11Homeobox A11. (316 aa)
NGFRNerve growth factor receptor. (429 aa)
STOX1Storkhead box 1. (980 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SIX1SIX homeobox 1. (284 aa)
GATA3Uncharacterized protein. (444 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HOXC11Homeobox C11. (369 aa)
CSF1Colony stimulating factor 1. (438 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (261 aa)
ARAndrogen receptor. (886 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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