STRINGSTRING
CUEDC2 CUEDC2 CCDC142 CCDC142 PLA2G10 PLA2G10 IL1R2 IL1R2 IL6 IL6 ZC3H12A ZC3H12A APPL1 APPL1 LOC105819868 LOC105819868 APPL2 APPL2 GPSM3 GPSM3 IL17A IL17A NLRC3 NLRC3 ADCY7 ADCY7 NOS2 NOS2 GBP5 GBP5 CLEC7A CLEC7A IL17RC IL17RC ABCD2 ABCD2 PDCD4 PDCD4 MAPK14 MAPK14 PLD4 PLD4 ALOX5 ALOX5 TNF TNF MEFV MEFV F2 F2 TREM2 TREM2 PPARA PPARA ABCD1 ABCD1 PER1 PER1 TICAM1 TICAM1 ANKRD42 ANKRD42 CD6 CD6 BAP1 BAP1 LOC105812575 LOC105812575 IL17C IL17C NOD2 NOD2 PLA2G3 PLA2G3 STAT3 STAT3 MYD88 MYD88 PYCARD PYCARD CARD9 CARD9 EPHB2 EPHB2 IL17RA IL17RA APOD APOD HIF1A HIF1A LEP LEP IL17D IL17D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CUEDC2CUE domain containing 2. (287 aa)
CCDC142Coiled-coil domain containing 142. (749 aa)
PLA2G10Phospholipase A(2). (165 aa)
IL1R2Interleukin 1 receptor type 2. (424 aa)
IL6Uncharacterized protein. (211 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (661 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (591 aa)
GPSM3G protein signaling modulator 3. (160 aa)
IL17AInterleukin 17A. (153 aa)
NLRC3NLR family CARD domain containing 3. (1103 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1104 aa)
GBP5Guanylate binding protein 5. (583 aa)
CLEC7AUncharacterized protein. (62 aa)
IL17RCInterleukin 17 receptor C. (775 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
PDCD4Programmed cell death 4. (450 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
PLD4Phospholipase D family member 4. (502 aa)
ALOX5Arachidonate 5-lipoxygenase. (675 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
MEFVMEFV innate immuity regulator, pyrin. (772 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
ABCD1ATP binding cassette subfamily D member 1. (746 aa)
PER1Period circadian regulator 1. (1292 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (692 aa)
ANKRD42Ankyrin repeat domain 42. (517 aa)
CD6CD6 molecule. (670 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (730 aa)
LOC105812575Phospholipase D4-like. (76 aa)
IL17CInterleukin 17C. (197 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
PLA2G3Phospholipase A2 group III. (506 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
PYCARDPYD and CARD domain containing. (195 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
EPHB2EPH receptor B2. (1039 aa)
IL17RAInterleukin 17 receptor A. (847 aa)
APODApolipoprotein D. (189 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
IL17DInterleukin 17D. (200 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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