35 items (Propithecus coquereli) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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protein homology

Your Input:
	EGFR	Receptor protein-tyrosine kinase. (1210 aa)
	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
	DDR2	Discoidin domain receptor tyrosine kinase 2. (855 aa)
	MTBP	MDM2 binding protein. (724 aa)
	CCND3	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (575 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (671 aa)
	ENSPCOP00000025432	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
	UBE2E2	Ubiquitin conjugating enzyme E2 E2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
	HYAL1	Hyaluronidase. (435 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	ENSPCOP00000002776	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
	RRM2	Ribonucleotide reductase regulatory subunit M2. (386 aa)
	CCND2	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
	SASS6	SAS-6 centriolar assembly protein. (657 aa)
	PLCB1	Phosphoinositide phospholipase C. (1010 aa)
	ANXA1	Annexin. (346 aa)
	PLRG1	Pleiotropic regulator 1. (515 aa)
	AIF1	Allograft inflammatory factor 1. (147 aa)
	RPTOR	Regulatory associated protein of MTOR complex 1. (1281 aa)
	CDK10	Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (360 aa)
	LSM11	LSM11, U7 small nuclear RNA associated. (352 aa)
	STOX1	Storkhead box 1. (980 aa)
	KMT2E	Lysine methyltransferase 2E. (1866 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (509 aa)
	ANKRD17	Ankyrin repeat domain 17. (2391 aa)
	RGCC	Regulator of cell cycle. (137 aa)
	MEPCE	Methylphosphate capping enzyme. (686 aa)
	STIL	STIL centriolar assembly protein. (1202 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1605 aa)
	ENSPCOP00000028627	Cyclin_C domain-containing protein. (259 aa)
	RRM1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	CDC6	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (555 aa)
	ADAM17	ADAM metallopeptidase domain 17. (757 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	EGFR	ENSPCOP00000030128	ENSPCOP00000018322	ADAM metallopeptidase domain 17.	Receptor protein-tyrosine kinase.	0.401
AIF1	AKT1	ENSPCOP00000008881	ENSPCOP00000028969	Allograft inflammatory factor 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.566
AKT1	AIF1	ENSPCOP00000028969	ENSPCOP00000008881	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Allograft inflammatory factor 1.	0.566
AKT1	CCND2	ENSPCOP00000028969	ENSPCOP00000005111	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.410
AKT1	CCND3	ENSPCOP00000028969	ENSPCOP00000021738	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.417
AKT1	EGFR	ENSPCOP00000028969	ENSPCOP00000018322	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Receptor protein-tyrosine kinase.	0.649
AKT1	ENSPCOP00000002776	ENSPCOP00000028969	ENSPCOP00000002776	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.564
AKT1	ENSPCOP00000025432	ENSPCOP00000028969	ENSPCOP00000025432	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.564
AKT1	ENSPCOP00000028627	ENSPCOP00000028969	ENSPCOP00000028627	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Cyclin_C domain-containing protein.	0.417
AKT1	KMT2E	ENSPCOP00000028969	ENSPCOP00000014016	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Lysine methyltransferase 2E.	0.634
AKT1	MTBP	ENSPCOP00000028969	ENSPCOP00000018796	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MDM2 binding protein.	0.400
AKT1	RPTOR	ENSPCOP00000028969	ENSPCOP00000009957	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Regulatory associated protein of MTOR complex 1.	0.942
ANXA1	EGFR	ENSPCOP00000005661	ENSPCOP00000018322	Annexin.	Receptor protein-tyrosine kinase.	0.466
CCND2	AKT1	ENSPCOP00000005111	ENSPCOP00000028969	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.410
CCND2	CCND3	ENSPCOP00000005111	ENSPCOP00000021738	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.791
CCND2	EGFR	ENSPCOP00000005111	ENSPCOP00000018322	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Receptor protein-tyrosine kinase.	0.445
CCND2	ENSPCOP00000028627	ENSPCOP00000005111	ENSPCOP00000028627	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin_C domain-containing protein.	0.795
CCND3	AKT1	ENSPCOP00000021738	ENSPCOP00000028969	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.417
CCND3	CCND2	ENSPCOP00000021738	ENSPCOP00000005111	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.791
CDC6	CUL4A	ENSPCOP00000029402	ENSPCOP00000022268	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	Cullin 4A; Belongs to the cullin family.	0.475