16 items (Propithecus coquereli) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1125 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (598 aa)
	RFFL	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (362 aa)
	BOK	BCL2 family apoptosis regulator BOK. (213 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	GCG	Glucagon. (180 aa)
	SIRT2	Sirtuin 2. (469 aa)
	BCL2L1	BCL2 like 1. (233 aa)
	PAK2	Non-specific serine/threonine protein kinase. (492 aa)
	CXCR3	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
	PTGIS	Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
	CIDEA	Cell death inducing DFFA like effector a. (231 aa)
	DFFA	DNA fragmentation factor subunit alpha. (331 aa)
	RNF34	Ring finger protein 34. (489 aa)
	FAP	Fibroblast activation protein alpha; Belongs to the peptidase S9B family. (760 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2L1	TP53	ENSPCOP00000020737	ENSPCOP00000031758	BCL2 like 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.995
BOK	TP53	ENSPCOP00000004561	ENSPCOP00000031758	BCL2 family apoptosis regulator BOK.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.595
FAP	GCG	ENSPCOP00000028779	ENSPCOP00000010230	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	Glucagon.	0.568
GCG	FAP	ENSPCOP00000010230	ENSPCOP00000028779	Glucagon.	Fibroblast activation protein alpha; Belongs to the peptidase S9B family.	0.568
RFFL	RNF34	ENSPCOP00000006278	ENSPCOP00000026387	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Ring finger protein 34.	0.582
RFFL	TP53	ENSPCOP00000006278	ENSPCOP00000031758	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.609
RNF34	RFFL	ENSPCOP00000026387	ENSPCOP00000006278	Ring finger protein 34.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.582
RNF34	TP53	ENSPCOP00000026387	ENSPCOP00000031758	Ring finger protein 34.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.643
SIRT2	TP53	ENSPCOP00000011807	ENSPCOP00000031758	Sirtuin 2.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.736
TP53	BCL2L1	ENSPCOP00000031758	ENSPCOP00000020737	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BCL2 like 1.	0.995
TP53	BOK	ENSPCOP00000031758	ENSPCOP00000004561	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	BCL2 family apoptosis regulator BOK.	0.595
TP53	RFFL	ENSPCOP00000031758	ENSPCOP00000006278	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase.	0.609
TP53	RNF34	ENSPCOP00000031758	ENSPCOP00000026387	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ring finger protein 34.	0.643
TP53	SIRT2	ENSPCOP00000031758	ENSPCOP00000011807	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Sirtuin 2.	0.736