STRINGSTRING
STAB1 STAB1 ROCK1 ROCK1 PLK2 PLK2 HSPG2 HSPG2 SARS1 SARS1 TBC1D31 TBC1D31 EPN1 EPN1 ENSPCOP00000004028 ENSPCOP00000004028 THBS2 THBS2 ENSPCOP00000003159 ENSPCOP00000003159 HHEX HHEX ENSPCOP00000001819 ENSPCOP00000001819 NAXE NAXE FOXJ2 FOXJ2 TGFB2 TGFB2 SULF1 SULF1 E2F2 E2F2 NIBAN2 NIBAN2 GPR4 GPR4 FOXO4 FOXO4 KRIT1 KRIT1 CTNNB1 CTNNB1 EMILIN1 EMILIN1 CXCL10 CXCL10 THBS1 THBS1 KLF2 KLF2 MECP2 MECP2 FASLG FASLG CREB3L1 CREB3L1 TNMD TNMD CCN6 CCN6 ATF2 ATF2 NF1 NF1 AMOT AMOT SPRY2 SPRY2 THBS4 THBS4 SPRED1 SPRED1 GHRL GHRL SYNJ2BP SYNJ2BP FOXC1 FOXC1 GDF2 GDF2 SERPINF1 SERPINF1 HRG HRG NPPB NPPB SEMA6A SEMA6A YJEFN3 YJEFN3 VASH1 VASH1 ECSCR ECSCR GADD45A GADD45A GTF2I GTF2I WNT4 WNT4 PDE3B PDE3B PML PML AGO1 AGO1 DAB2IP DAB2IP SEMA4A SEMA4A CD160 CD160 ADAMTS1 ADAMTS1 SPINK5 SPINK5 ADAMTS9 ADAMTS9 COL4A2 COL4A2 ANGPT2 ANGPT2 TIE1 TIE1 ADGRB2 ADGRB2 HOXA5 HOXA5 RGCC RGCC PIK3CB PIK3CB SLC12A2 SLC12A2 SPARC SPARC ISM1 ISM1 ALOX5 ALOX5 TNF TNF ENSPCOP00000014590 ENSPCOP00000014590 ATP2B4 ATP2B4 ABCC8 ABCC8 CNMD CNMD DCN DCN MINAR1 MINAR1 ROCK2 ROCK2 NPR1 NPR1 SERPINE1 SERPINE1 EPHA2 EPHA2 EPN2 EPN2 SEMA3E SEMA3E ANGPT4 ANGPT4 HGS HGS COL4A3 COL4A3 ANGPTL7 ANGPTL7 KLF4 KLF4 PTPRM PTPRM TEK TEK STAT1 STAT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAB1Stabilin 1. (2566 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
HSPG2Heparan sulfate proteoglycan 2. (4370 aa)
SARS1Seryl-tRNA synthetase. (538 aa)
TBC1D31TBC1 domain family member 31. (1062 aa)
EPN1Epsin 1. (575 aa)
ENSPCOP00000004028ENTH domain-containing protein. (534 aa)
THBS2Thrombospondin 2. (1172 aa)
ENSPCOP00000003159IGFBP N-terminal domain-containing protein. (230 aa)
HHEXHematopoietically expressed homeobox. (271 aa)
ENSPCOP00000001819Uncharacterized protein. (406 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
FOXJ2Forkhead box J2. (527 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SULF1Sulfatase 1. (863 aa)
E2F2E2F transcription factor 2. (435 aa)
NIBAN2Niban apoptosis regulator 2. (748 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
FOXO4Forkhead box O4. (506 aa)
KRIT1ANK_REP_REGION domain-containing protein. (723 aa)
CTNNB1Catenin beta 1. (781 aa)
EMILIN1Elastin microfibril interfacer 1. (1022 aa)
CXCL10C-X-C motif chemokine. (98 aa)
THBS1Thrombospondin 1. (1185 aa)
KLF2Kruppel like factor 2. (356 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (500 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (278 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (520 aa)
TNMDTenomodulin. (320 aa)
CCN6CTCK domain-containing protein. (130 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
NF1Neurofibromin 1. (2841 aa)
AMOTAngiomotin. (1083 aa)
SPRY2Sprouty RTK signaling antagonist 2. (314 aa)
THBS4Thrombospondin 4. (959 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
GHRLGhrelin and obestatin prepropeptide. (116 aa)
SYNJ2BPSynaptojanin 2 binding protein. (134 aa)
FOXC1Forkhead box C1. (535 aa)
GDF2Growth differentiation factor 2. (427 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
HRGHistidine rich glycoprotein. (468 aa)
NPPBNatriuretic peptide B. (132 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
YJEFN3YjeF N-terminal domain-containing protein. (293 aa)
VASH1Vasohibin 1. (363 aa)
ECSCRUncharacterized protein. (205 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
GTF2IGeneral transcription factor IIi. (998 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PDE3BPhosphodiesterase. (1047 aa)
PMLPromyelocytic leukemia. (887 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
DAB2IPDAB2 interacting protein. (1209 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (761 aa)
CD160CD160 molecule. (220 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
SPINK5Uncharacterized protein. (775 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1838 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
ANGPT2Angiopoietin 2. (496 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa)
ADGRB2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1564 aa)
HOXA5Homeobox A5. (270 aa)
RGCCRegulator of cell cycle. (137 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SLC12A2Solute carrier family 12 member 2. (1153 aa)
SPARCSecreted protein acidic and cysteine rich. (303 aa)
ISM1Isthmin 1. (463 aa)
ALOX5Arachidonate 5-lipoxygenase. (675 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
ENSPCOP00000014590Uncharacterized protein. (118 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
ABCC8ATP binding cassette subfamily C member 8. (1582 aa)
CNMDChondromodulin. (287 aa)
DCNDecorin; May affect the rate of fibrils formation. (290 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (714 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1361 aa)
NPR1Guanylate cyclase. (1058 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
EPHA2EPH receptor A2. (976 aa)
EPN2ENTH domain-containing protein. (641 aa)
SEMA3ESema domain-containing protein; Belongs to the semaphorin family. (390 aa)
ANGPT4Angiopoietin 4. (499 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
COL4A3Collagen type IV alpha 3 chain. (1545 aa)
ANGPTL7Angiopoietin like 7. (344 aa)
KLF4Uncharacterized protein. (486 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1440 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
STAT1Signal transducer and activator of transcription. (794 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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