43 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSPCOP00000015642	DJ-1_PfpI domain-containing protein. (175 aa)
	FEM1B	Fem-1 homolog B. (627 aa)
	TNFAIP3	TNF alpha induced protein 3. (792 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	TMC8	Transmembrane channel-like protein. (729 aa)
	PARK7	DJ-1_PfpI domain-containing protein. (155 aa)
	RNF34	Ring finger protein 34. (489 aa)
	FAF1	Fas associated factor 1. (627 aa)
	THBS1	Thrombospondin 1. (1185 aa)
	FGA	Fib_alpha domain-containing protein. (649 aa)
	ENSPCOP00000023392	Uncharacterized protein. (157 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (390 aa)
	BCL2L1	BCL2 like 1. (233 aa)
	STK3	Serine/threonine kinase 3. (500 aa)
	MAL	Mal, T cell differentiation protein. (153 aa)
	SFRP2	Secreted frizzled related protein 2. (295 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (703 aa)
	ICAM1	Intercellular adhesion molecule 1. (533 aa)
	ZSWIM2	Zinc finger SWIM-type containing 2. (636 aa)
	TIMP3	TIMP metallopeptidase inhibitor 3. (211 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (500 aa)
	FAIM	Fas apoptotic inhibitory molecule. (191 aa)
	STK4	Serine/threonine kinase 4. (487 aa)
	FGG	Fibrinogen gamma chain. (456 aa)
	ENSPCOP00000012342	RING-type domain-containing protein. (80 aa)
	SERPINE1	Serpin family E member 1; Belongs to the serpin family. (402 aa)
	BMP5	Bone morphogenetic protein 5. (379 aa)
	ARHGEF2	Rho/Rac guanine nucleotide exchange factor 2. (1013 aa)
	NOS3	Nitric oxide synthase 3. (994 aa)
	LGALS3	Galectin. (250 aa)
	FGB	Fibrinogen beta chain. (492 aa)
	ATF3	Activating transcription factor 3. (181 aa)
	RFFL	Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (362 aa)
	MADD	MAP kinase activating death domain. (1647 aa)
	FAIM2	Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa)
	LOC105825287	DJ-1_PfpI domain-containing protein. (189 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (298 aa)
	HMOX1	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
	ENSPCOP00000004135	Uncharacterized protein. (520 aa)
	SKIL	SKI like proto-oncogene. (664 aa)
	PMAIP1	Uncharacterized protein. (54 aa)
	TMBIM1	Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (311 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF2	BMPR1B	ENSPCOP00000010180	ENSPCOP00000014979	Rho/Rac guanine nucleotide exchange factor 2.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.409
ARHGEF2	GSK3B	ENSPCOP00000010180	ENSPCOP00000022838	Rho/Rac guanine nucleotide exchange factor 2.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.416
ATF3	GSK3B	ENSPCOP00000006485	ENSPCOP00000022838	Activating transcription factor 3.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.559
BCL2L1	ENSPCOP00000015642	ENSPCOP00000020737	ENSPCOP00000015642	BCL2 like 1.	DJ-1_PfpI domain-containing protein.	0.793
BCL2L1	FAIM2	ENSPCOP00000020737	ENSPCOP00000005244	BCL2 like 1.	Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family.	0.424
BCL2L1	GSK3B	ENSPCOP00000020737	ENSPCOP00000022838	BCL2 like 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.530
BCL2L1	LOC105825287	ENSPCOP00000020737	ENSPCOP00000004558	BCL2 like 1.	DJ-1_PfpI domain-containing protein.	0.793
BCL2L1	PARK7	ENSPCOP00000020737	ENSPCOP00000029394	BCL2 like 1.	DJ-1_PfpI domain-containing protein.	0.793
BCL2L1	PMAIP1	ENSPCOP00000020737	ENSPCOP00000002848	BCL2 like 1.	Uncharacterized protein.	0.976
BMP5	BMPR1B	ENSPCOP00000010725	ENSPCOP00000014979	Bone morphogenetic protein 5.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.946
BMPR1B	ARHGEF2	ENSPCOP00000014979	ENSPCOP00000010180	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Rho/Rac guanine nucleotide exchange factor 2.	0.409
BMPR1B	BMP5	ENSPCOP00000014979	ENSPCOP00000010725	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 5.	0.946
BMPR1B	SKIL	ENSPCOP00000014979	ENSPCOP00000003945	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	SKI like proto-oncogene.	0.469
BMPR1B	TNFAIP3	ENSPCOP00000014979	ENSPCOP00000030793	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	TNF alpha induced protein 3.	0.403
ENSPCOP00000015642	BCL2L1	ENSPCOP00000015642	ENSPCOP00000020737	DJ-1_PfpI domain-containing protein.	BCL2 like 1.	0.793
ENSPCOP00000015642	PTEN	ENSPCOP00000015642	ENSPCOP00000001519	DJ-1_PfpI domain-containing protein.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.621
FAIM2	BCL2L1	ENSPCOP00000005244	ENSPCOP00000020737	Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family.	BCL2 like 1.	0.424
FGA	FGB	ENSPCOP00000023707	ENSPCOP00000007560	Fib_alpha domain-containing protein.	Fibrinogen beta chain.	0.999
FGA	FGG	ENSPCOP00000023707	ENSPCOP00000013602	Fib_alpha domain-containing protein.	Fibrinogen gamma chain.	0.999
FGA	HGF	ENSPCOP00000023707	ENSPCOP00000018290	Fib_alpha domain-containing protein.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.575