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CPT1B CPT1B ANKZF1 ANKZF1 LOC105806743 LOC105806743 SPART SPART MIEF1 MIEF1 PGRMC1 PGRMC1 MAOA MAOA ENSPCOP00000021800 ENSPCOP00000021800 MFF MFF TOMM20L TOMM20L TOMM5 TOMM5 FAM210B FAM210B LOC105806966 LOC105806966 ACSL3 ACSL3 BCL2 BCL2 BCL2L1 BCL2L1 MARCHF5 MARCHF5 ENSPCOP00000019899 ENSPCOP00000019899 CYP27B1 CYP27B1 DMPK DMPK MAVS MAVS STARD7 STARD7 SFXN2 SFXN2 GPAT2 GPAT2 SARM1 SARM1 DNAJC11 DNAJC11 BCL2L11 BCL2L11 ENSPCOP00000018904 ENSPCOP00000018904 SPATA18 SPATA18 NLRX1 NLRX1 CPT1A CPT1A TOMM6 TOMM6 PLD6 PLD6 ENSPCOP00000001321 ENSPCOP00000001321 MFSD11 MFSD11 LOC105820977 LOC105820977 ARMC12 ARMC12 MYO19 MYO19 TMEM205 TMEM205 PMAIP1 PMAIP1 TIGAR TIGAR MIEF2 MIEF2 MFN2 MFN2 LOC105820322 LOC105820322 MICOS10 MICOS10 PPP2R2B PPP2R2B TOMM70 TOMM70 HADHB HADHB HAX1 HAX1 GDAP1 GDAP1 MGARP MGARP RHOT2 RHOT2 ENSPCOP00000017348 ENSPCOP00000017348 PINK1 PINK1 LRRK2 LRRK2 MTX3 MTX3 MTERF3 MTERF3 ACSL4 ACSL4 FOXO3 FOXO3 MTX2 MTX2 VPS13C VPS13C MCL1 MCL1 CISD1 CISD1 ATF2 ATF2 TOMM7 TOMM7 LOC105816759 LOC105816759 ENSPCOP00000027604 ENSPCOP00000027604 SLC25A46 SLC25A46 TOMM34 TOMM34 SYNJ2BP SYNJ2BP TOMM22 TOMM22 RTN4IP1 RTN4IP1 GDAP1L1 GDAP1L1 ACACB ACACB BAD BAD ENSPCOP00000030899 ENSPCOP00000030899 AMBRA1 AMBRA1 RPS6KB1 RPS6KB1 LOC105821427 LOC105821427 ATAD1 ATAD1 EXD2 EXD2 MTX1 MTX1 BID BID ENSPCOP00000017250 ENSPCOP00000017250 RHOT1 RHOT1 SAMM50 SAMM50 TOMM40 TOMM40 ENSPCOP00000009641 ENSPCOP00000009641 GPAM GPAM USP30 USP30 AGPAT5 AGPAT5 NIPSNAP2 NIPSNAP2 PRKN PRKN RPS27A RPS27A FUNDC1 FUNDC1 NEU4 NEU4 TOMM40L TOMM40L VAT1 VAT1 OPA1 OPA1 COASY COASY AIFM2 AIFM2 BNIP3 BNIP3 SLC8A3 SLC8A3 ACSL1 ACSL1 TSPO TSPO MTCH2 MTCH2 CISD2 CISD2 MFN1 MFN1 BMF BMF ENSPCOP00000012718 ENSPCOP00000012718 HK2 HK2 KMO KMO MUL1 MUL1 RAB32 RAB32 QTRT1 QTRT1 MSTO1 MSTO1 PGAM5 PGAM5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
ANKZF1Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1. (722 aa)
LOC105806743MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (56 aa)
SPARTSpartin. (563 aa)
MIEF1Mitochondrial elongation factor 1. (463 aa)
PGRMC1Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (195 aa)
MAOAAmine oxidase. (528 aa)
ENSPCOP00000021800Uncharacterized protein. (175 aa)
MFFMitochondrial fission factor. (313 aa)
TOMM20LTranslocase of outer mitochondrial membrane 20 like. (152 aa)
TOMM5Translocase of outer mitochondrial membrane 5. (70 aa)
FAM210BFamily with sequence similarity 210 member B. (193 aa)
LOC105806966MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (68 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (673 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
BCL2L1BCL2 like 1. (233 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (278 aa)
ENSPCOP00000019899Miro domain-containing protein. (554 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
DMPKDM1 protein kinase. (630 aa)
MAVSMitochondrial antiviral signaling protein. (514 aa)
STARD7StAR related lipid transfer domain containing 7. (339 aa)
SFXN2Sidoreflexin. (322 aa)
GPAT2Glycerol-3-phosphate acyltransferase 2, mitochondrial. (794 aa)
SARM1Sterile alpha and TIR motif containing 1. (724 aa)
DNAJC11DnaJ heat shock protein family (Hsp40) member C11. (559 aa)
BCL2L11BCL2 like 11. (200 aa)
ENSPCOP00000018904Ubiquitin-like domain-containing protein. (131 aa)
SPATA18Spermatogenesis associated 18. (493 aa)
NLRX1NLR family member X1. (975 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (697 aa)
TOMM6Translocase of outer mitochondrial membrane 6. (74 aa)
PLD6Phospholipase D family member 6. (247 aa)
ENSPCOP00000001321Uncharacterized protein. (49 aa)
MFSD11Major facilitator superfamily domain containing 11. (449 aa)
LOC105820977Uncharacterized protein. (48 aa)
ARMC12Armadillo repeat containing 12. (366 aa)
MYO19Myosin XIX; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (958 aa)
TMEM205Transmembrane protein 205. (189 aa)
PMAIP1Uncharacterized protein. (54 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
MIEF2Mitochondrial elongation factor 2. (454 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
LOC105820322Ubiquitin-like domain-containing protein. (77 aa)
MICOS10MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (78 aa)
PPP2R2BSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (509 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (553 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (278 aa)
GDAP1Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa)
MGARPMitochondria localized glutamic acid rich protein. (240 aa)
RHOT2Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (621 aa)
ENSPCOP00000017348Uncharacterized protein. (67 aa)
PINK1PTEN induced kinase 1. (581 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
MTX3Metaxin. (286 aa)
MTERF3Mitochondrial transcription termination factor 3. (353 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (711 aa)
FOXO3Forkhead box O3. (672 aa)
MTX2Metaxin 2. (166 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3076 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (350 aa)
CISD1CDGSH iron sulfur domain 1. (108 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
TOMM7Translocase of outer mitochondrial membrane 7. (55 aa)
LOC105816759Ubiquitin-like domain-containing protein. (156 aa)
ENSPCOP00000027604Uncharacterized protein. (196 aa)
SLC25A46Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (205 aa)
TOMM34Translocase of outer mitochondrial membrane 34. (309 aa)
SYNJ2BPSynaptojanin 2 binding protein. (134 aa)
TOMM22Translocase of outer mitochondrial membrane 22. (142 aa)
RTN4IP1Reticulon 4 interacting protein 1. (396 aa)
GDAP1L1Ganglioside induced differentiation associated protein 1 like 1. (383 aa)
ACACBAcetyl-CoA carboxylase beta. (2172 aa)
BADBCL2 associated agonist of cell death. (168 aa)
ENSPCOP00000030899PlsC domain-containing protein. (362 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1270 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)
LOC105821427Uncharacterized protein. (301 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (383 aa)
EXD2Exonuclease 3'-5' domain containing 2. (621 aa)
MTX1Metaxin 1. (466 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (220 aa)
ENSPCOP00000017250ZnF_CDGSH domain-containing protein. (120 aa)
RHOT1Uncharacterized protein. (752 aa)
SAMM50SAMM50 sorting and assembly machinery component. (469 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
ENSPCOP00000009641Uncharacterized protein. (136 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (787 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
AGPAT5PlsC domain-containing protein. (364 aa)
NIPSNAP2Nipsnap homolog 2. (286 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
RPS27ARibosomal protein S27a. (156 aa)
FUNDC1FUN14 domain containing 1. (155 aa)
NEU4Neuraminidase 4. (487 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (308 aa)
VAT1Vesicle amine transport 1. (391 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (997 aa)
COASYCTP_transf_like domain-containing protein. (564 aa)
AIFM2Apoptosis inducing factor mitochondria associated 2. (373 aa)
BNIP3Uncharacterized protein. (235 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
ACSL1Acyl-CoA synthetase long chain family member 1. (664 aa)
TSPOTranslocator protein. (169 aa)
MTCH2Mitochondrial carrier 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (271 aa)
CISD2ZnF_CDGSH domain-containing protein. (135 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (722 aa)
BMFBcl2 modifying factor. (184 aa)
ENSPCOP00000012718Ubiquitin-like domain-containing protein. (74 aa)
HK2Hexokinase 2. (841 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (467 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
RAB32RAB32, member RAS oncogene family. (225 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (403 aa)
MSTO1Misato mitochondrial distribution and morphology regulator 1. (570 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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