43 items (Propithecus coquereli) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	SCN5A	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	HDAC6	Histone deacetylase 6. (1203 aa)
	FXYD1	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
	LRP8	LDL receptor related protein 8. (956 aa)
	KCNMA1	Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	LRRK2	Leucine rich repeat kinase 2. (2427 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (525 aa)
	FLOT2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
	RANGRF	RAN guanine nucleotide release factor. (186 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	PTCH1	Patched 1. (1449 aa)
	PTGIS	Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
	SRC	Tyrosine-protein kinase. (543 aa)
	CAVIN1	Caveolae associated protein 1. (389 aa)
	ENSPCOP00000014320	Uncharacterized protein. (415 aa)
	MLC1	Modulator of VRAC current 1. (378 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
	CBL	Cbl proto-oncogene. (891 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	CLN3	Battenin. (438 aa)
	NOS3	Nitric oxide synthase 3. (994 aa)
	DLC1	DLC1 Rho GTPase activating protein. (1125 aa)
	CDH1	Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
	PLPP1	Phospholipid phosphatase 1. (286 aa)
	SELE	Selectin E. (610 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (461 aa)
	CAVIN2	Uncharacterized protein. (424 aa)
	FLOT1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
	PLPP2	Phospholipid phosphatase 2. (304 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	CDH13	Cadherin 13. (713 aa)
	CAVIN3	Caveolae associated protein 3. (286 aa)
	EHD2	EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
	STOM	Stomatin. (288 aa)
	ADTRP	Androgen dependent TFPI regulating protein. (237 aa)
	SORBS1	Sorbin and SH3 domain containing 1. (1294 aa)
	MYOF	Myoferlin. (2061 aa)
	ASAH2	Neutral ceramidase. (726 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASAH2	PLPP1	ENSPCOP00000000930	ENSPCOP00000008107	Neutral ceramidase.	Phospholipid phosphatase 1.	0.853
ASAH2	PLPP2	ENSPCOP00000000930	ENSPCOP00000005152	Neutral ceramidase.	Phospholipid phosphatase 2.	0.853
ATP2B4	FXYD1	ENSPCOP00000014127	ENSPCOP00000027189	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.408
ATP2B4	NOS3	ENSPCOP00000014127	ENSPCOP00000009840	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Nitric oxide synthase 3.	0.743
ATP2B4	SCN5A	ENSPCOP00000014127	ENSPCOP00000006360	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.540
CAV1	CAV2	ENSPCOP00000025045	ENSPCOP00000026838	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.997
CAV1	CAV3	ENSPCOP00000025045	ENSPCOP00000004480	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.902
CAV1	CAVIN1	ENSPCOP00000025045	ENSPCOP00000018526	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1.	0.897
CAV1	CAVIN2	ENSPCOP00000025045	ENSPCOP00000006055	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.549
CAV1	CAVIN3	ENSPCOP00000025045	ENSPCOP00000003592	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 3.	0.647
CAV1	CD36	ENSPCOP00000025045	ENSPCOP00000010616	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	CD36 molecule; Belongs to the CD36 family.	0.452
CAV1	EHD2	ENSPCOP00000025045	ENSPCOP00000003323	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.465
CAV1	ENSPCOP00000014320	ENSPCOP00000025045	ENSPCOP00000014320	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.549
CAV1	FLOT1	ENSPCOP00000025045	ENSPCOP00000005467	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.772
CAV1	FLOT2	ENSPCOP00000025045	ENSPCOP00000023202	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.756
CAV1	KCNMA1	ENSPCOP00000025045	ENSPCOP00000025071	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Potassium calcium-activated channel subfamily M alpha 1.	0.482
CAV1	LRP8	ENSPCOP00000025045	ENSPCOP00000025208	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	LDL receptor related protein 8.	0.502
CAV1	MYOF	ENSPCOP00000025045	ENSPCOP00000001942	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myoferlin.	0.549
CAV1	NOS3	ENSPCOP00000025045	ENSPCOP00000009840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 3.	0.940
CAV1	SRC	ENSPCOP00000025045	ENSPCOP00000018583	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase.	0.931