STRINGSTRING
ADAMTS3 ADAMTS3 ABI3BP ABI3BP MFAP4 MFAP4 CBY3 CBY3 MMP8 MMP8 P3H2 P3H2 TGFB2 TGFB2 GOLPH3 GOLPH3 ANOS1 ANOS1 OLFML2B OLFML2B LTBP4 LTBP4 PODNL1 PODNL1 COL15A1 COL15A1 ZPLD1 ZPLD1 CTXN1 CTXN1 MMRN2 MMRN2 ADAMTS6 ADAMTS6 TECTB TECTB PAQR4 PAQR4 HSPA12B HSPA12B MEOX2 MEOX2 PAPLN PAPLN EPYC EPYC CXorf58 CXorf58 SPDYA SPDYA CRISP2 CRISP2 PKHD1L1 PKHD1L1 LOC105808463 LOC105808463 CLC CLC GPC1 GPC1 ENSPCOP00000004862 ENSPCOP00000004862 ANG ANG C2orf80 C2orf80 LOXL1 LOXL1 NAALAD2 NAALAD2 MMP19 MMP19 ASPN ASPN FAM126B FAM126B PXDN PXDN COL18A1 COL18A1 AGRN AGRN TGFB3 TGFB3 NCAN NCAN ADNP2 ADNP2 MMP2 MMP2 BCL2L10 BCL2L10 PAPPA PAPPA TGM2 TGM2 SNED1 SNED1 TECTA TECTA TMPRSS3 TMPRSS3 IL7 IL7 COL4A3 COL4A3 DEFB123 DEFB123 ADAMTS5 ADAMTS5 COL6A2 COL6A2 EMID1 EMID1 UCMA UCMA SSC5D SSC5D PMP22 PMP22 ALG11 ALG11 SERPINE1 SERPINE1 IL1B IL1B LAMA4 LAMA4 ERBIN ERBIN VTN VTN ZP2 ZP2 TUT1 TUT1 FBN2 FBN2 LIM2 LIM2 MMP10 MMP10 MMP9 MMP9 RWDD2A RWDD2A DCN DCN LTBP1 LTBP1 TIMP2 TIMP2 CCN2 CCN2 BGN BGN COL26A1 COL26A1 EGFL7 EGFL7 COL8A2 COL8A2 CPZ CPZ EGFLAM EGFLAM TFPI2 TFPI2 C6orf15 C6orf15 LOC105815024 LOC105815024 CILP CILP TIMP3 TIMP3 TNF TNF ENSPCOP00000015683 ENSPCOP00000015683 APLP1 APLP1 SMOC1 SMOC1 PI3 PI3 LOC105811813 LOC105811813 ACHE ACHE AMELX AMELX ADAMTSL5 ADAMTSL5 HAPLN2 HAPLN2 FBLN2 FBLN2 BAG1 BAG1 OLFML2A OLFML2A ICAM1 ICAM1 ADAMTS9 ADAMTS9 ENSPCOP00000018033 ENSPCOP00000018033 COL8A1 COL8A1 ENSPCOP00000018647 ENSPCOP00000018647 MMP11 MMP11 LOX LOX MMP28 MMP28 TPST1 TPST1 LTBP3 LTBP3 NOSTRIN NOSTRIN ZP3 ZP3 COL4A1 COL4A1 SPOCK2 SPOCK2 KERA KERA HPSE2 HPSE2 MATN1 MATN1 GFOD1 GFOD1 NDP NDP LOXL2 LOXL2 COL4A5 COL4A5 ADAMTSL2 ADAMTSL2 LAX1 LAX1 TGFBR3L TGFBR3L ANGPT1 ANGPT1 NCAM1 NCAM1 LOC105826911 LOC105826911 COMP COMP COCH COCH EMILIN2 EMILIN2 SERPINE2 SERPINE2 MMP23B MMP23B HAPLN4 HAPLN4 SFSWAP SFSWAP PCSK6 PCSK6 ENSPCOP00000023872 ENSPCOP00000023872 SDC1 SDC1 VEGFA VEGFA PRELP PRELP F3 F3 COLQ COLQ MLEC MLEC CDK2AP1 CDK2AP1 THBS1 THBS1 FN1 FN1 CRISP3 CRISP3 ZP4 ZP4 CLEC7A CLEC7A SPOCK3 SPOCK3 CASK CASK SNORC SNORC GFOD2 GFOD2 GP1BA GP1BA FLRT2 FLRT2 GPLD1 GPLD1 COL12A1 COL12A1 THBS4 THBS4 FBN1 FBN1 EGFL8 EGFL8 ADAMTS10 ADAMTS10 COL11A2 COL11A2 FBLN5 FBLN5 LTBP2 LTBP2 SYNJ2BP SYNJ2BP FREM1 FREM1 ECM1 ECM1 MFAP1 MFAP1 AGT AGT OPTC OPTC ADAMTS13 ADAMTS13 PXYLP1 PXYLP1 WNT2 WNT2 SFRP1 SFRP1 ADAMTS4 ADAMTS4 CCBE1 CCBE1 FMOD FMOD KRT7 KRT7 COL6A3 COL6A3 COL7A1 COL7A1 RWDD2B RWDD2B ATAD1 ATAD1 BICC1 BICC1 CHADL CHADL MATN2 MATN2 OTOA OTOA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1160 aa)
ABI3BPABI family member 3 binding protein. (1756 aa)
MFAP4Microfibril associated protein 4. (286 aa)
CBY3Chibby family member 3. (227 aa)
MMP8Matrix metallopeptidase 8. (466 aa)
P3H2Prolyl 3-hydroxylase 2. (481 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
ANOS1Anosmin 1. (616 aa)
OLFML2BOlfactomedin like 2B. (756 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1626 aa)
PODNL1Podocan like 1. (509 aa)
COL15A1Collagen type XV alpha 1 chain. (1386 aa)
ZPLD1Zona pellucida like domain containing 1. (415 aa)
CTXN1Cortexin 1. (82 aa)
MMRN2Multimerin 2. (948 aa)
ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif 6. (1117 aa)
TECTBTectorin beta. (288 aa)
PAQR4Progestin and adipoQ receptor family member 4. (273 aa)
HSPA12BHeat shock protein family A (Hsp70) member 12B. (686 aa)
MEOX2Mesenchyme homeobox 2. (245 aa)
PAPLNPapilin, proteoglycan like sulfated glycoprotein. (1260 aa)
EPYCEpiphycan. (322 aa)
CXorf58Chromosome X open reading frame 58. (334 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (307 aa)
CRISP2Cysteine rich secretory protein 2; Belongs to the CRISP family. (268 aa)
PKHD1L1PKHD1 like 1. (3800 aa)
LOC105808463DRY_EERY domain-containing protein. (208 aa)
CLCGalectin. (142 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
ENSPCOP00000004862Uncharacterized protein. (454 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (146 aa)
C2orf80Chromosome 2 open reading frame 80. (193 aa)
LOXL1Lysyl oxidase like 1. (577 aa)
NAALAD2N-acetylated alpha-linked acidic dipeptidase 2. (711 aa)
MMP19Matrix metallopeptidase 19. (508 aa)
ASPNAsporin. (373 aa)
FAM126BFamily with sequence similarity 126 member B. (530 aa)
PXDNPeroxidasin. (1479 aa)
COL18A1Collagen type XVIII alpha 1 chain. (1729 aa)
AGRNAgrin. (2040 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
NCANNeurocan. (1310 aa)
ADNP2ADNP homeobox 2. (1084 aa)
MMP2Matrix metallopeptidase 2. (552 aa)
BCL2L10Uncharacterized protein. (192 aa)
PAPPAPappalysin 1. (1615 aa)
TGM2Transglutaminase 2. (542 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1290 aa)
TECTATectorin alpha. (2155 aa)
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (454 aa)
IL7Interleukin 7. (133 aa)
COL4A3Collagen type IV alpha 3 chain. (1545 aa)
DEFB123Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (67 aa)
ADAMTS5ADAM metallopeptidase with thrombospondin type 1 motif 5. (930 aa)
COL6A2Collagen type VI alpha 2 chain. (1012 aa)
EMID1EMI domain containing 1. (430 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (84 aa)
SSC5DScavenger receptor cysteine rich family member with 5 domains. (1486 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
ALG11Uncharacterized protein. (491 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
LAMA4Laminin subunit alpha 4. (1816 aa)
ERBINErbb2 interacting protein. (1377 aa)
VTNSMB domain-containing protein. (465 aa)
ZP2Zona pellucida glycoprotein 2. (746 aa)
TUT1RRM domain-containing protein. (912 aa)
FBN2Fibrillin 2. (2912 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
MMP10Matrix metallopeptidase 10; Belongs to the peptidase M10A family. (287 aa)
MMP9Matrix metallopeptidase 9. (709 aa)
RWDD2ARWD domain-containing protein. (292 aa)
DCNDecorin; May affect the rate of fibrils formation. (290 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1607 aa)
TIMP2TIMP metallopeptidase inhibitor 2. (220 aa)
CCN2Cellular communication network factor 2. (347 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (378 aa)
COL26A1Collagen type XXVI alpha 1 chain. (441 aa)
EGFL7EGF like domain multiple 7. (260 aa)
COL8A2Collagen type VIII alpha 2 chain. (695 aa)
CPZCarboxypeptidase Z. (655 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1017 aa)
TFPI2Tissue factor pathway inhibitor. (234 aa)
C6orf15Chromosome 6 open reading frame 15. (298 aa)
LOC105815024Uncharacterized protein. (512 aa)
CILPCartilage intermediate layer protein. (1182 aa)
TIMP3TIMP metallopeptidase inhibitor 3. (211 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
ENSPCOP00000015683Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (174 aa)
APLP1Amyloid beta precursor like protein 1. (653 aa)
SMOC1SPARC related modular calcium binding 1. (466 aa)
PI3Peptidase inhibitor 3. (117 aa)
LOC105811813Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (182 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (615 aa)
AMELXUncharacterized protein. (206 aa)
ADAMTSL5ADAMTS like 5. (462 aa)
HAPLN2Hyaluronan and proteoglycan link protein 2. (341 aa)
FBLN2Fibulin 2. (1224 aa)
BAG1BCL2 associated athanogene 1. (306 aa)
OLFML2AOlfactomedin like 2A. (650 aa)
ICAM1Intercellular adhesion molecule 1. (533 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1838 aa)
ENSPCOP00000018033HH_signal domain-containing protein. (110 aa)
COL8A1Collagen type VIII alpha 1 chain. (744 aa)
ENSPCOP00000018647SMB domain-containing protein. (205 aa)
MMP11Matrix metallopeptidase 11. (489 aa)
LOXLysyl oxidase. (416 aa)
MMP28Matrix metallopeptidase 28. (520 aa)
TPST1Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (355 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1306 aa)
NOSTRINNitric oxide synthase trafficking. (544 aa)
ZP3ZP domain-containing protein. (332 aa)
COL4A1Collagen type IV alpha 1 chain. (1670 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (424 aa)
KERAKeratocan. (353 aa)
HPSE2Heparanase 2 (inactive). (592 aa)
MATN1Matrilin 1. (499 aa)
GFOD1Glucose-fructose oxidoreductase domain containing 1. (390 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
LOXL2Lysyl oxidase like 2. (775 aa)
COL4A5Collagen type IV alpha 5 chain. (1516 aa)
ADAMTSL2ADAMTS like 2. (1052 aa)
LAX1Lymphocyte transmembrane adaptor 1. (426 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (313 aa)
ANGPT1Angiopoietin 1. (408 aa)
NCAM1Neural cell adhesion molecule 1. (866 aa)
LOC105826911Uncharacterized protein. (1548 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
COCHCochlin. (550 aa)
EMILIN2Elastin microfibril interfacer 2. (1061 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
MMP23BMatrix metallopeptidase 23B. (390 aa)
HAPLN4Hyaluronan and proteoglycan link protein 4. (456 aa)
SFSWAPSplicing factor SWAP. (1000 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (961 aa)
ENSPCOP00000023872Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (116 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
PRELPProline and arginine rich end leucine rich repeat protein. (380 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (294 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (459 aa)
MLECMalectin. (289 aa)
CDK2AP1Cyclin dependent kinase 2 associated protein 1. (96 aa)
THBS1Thrombospondin 1. (1185 aa)
FN1Fibronectin 1. (2290 aa)
CRISP3Cysteine rich secretory protein 3. (239 aa)
ZP4Zona pellucida glycoprotein 4. (536 aa)
CLEC7AUncharacterized protein. (62 aa)
SPOCK3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (391 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (915 aa)
SNORCSecondary ossification center associated regulator of chondrocyte maturation. (121 aa)
GFOD2Glucose-fructose oxidoreductase domain containing 2. (385 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (598 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (813 aa)
COL12A1Collagen type XII alpha 1 chain. (2907 aa)
THBS4Thrombospondin 4. (959 aa)
FBN1Fibrillin 1. (2871 aa)
EGFL8EGF like domain multiple 8. (292 aa)
ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10. (1103 aa)
COL11A2Collagen type XI alpha 2 chain. (1736 aa)
FBLN5Fibulin 5. (453 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1816 aa)
SYNJ2BPSynaptojanin 2 binding protein. (134 aa)
FREM1FRAS1 related extracellular matrix 1. (2149 aa)
ECM1Extracellular matrix protein 1. (570 aa)
MFAP1Microfibril associated protein 1. (439 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
OPTCOpticin. (331 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1355 aa)
PXYLP12-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family. (480 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
ADAMTS4ADAM metallopeptidase with thrombospondin type 1 motif 4. (837 aa)
CCBE1Collagen and calcium binding EGF domains 1. (408 aa)
FMODFibromodulin. (376 aa)
KRT7Keratin 7; Belongs to the intermediate filament family. (465 aa)
COL6A3Collagen type VI alpha 3 chain. (3101 aa)
COL7A1Collagen type VII alpha 1 chain. (2935 aa)
RWDD2BRWD domain-containing protein. (319 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (383 aa)
BICC1BicC family RNA binding protein 1. (972 aa)
CHADLChondroadherin like. (807 aa)
MATN2Matrilin 2. (956 aa)
OTOAOtoancorin. (1109 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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