STRINGSTRING
GUSB GUSB CTSC CTSC GRN GRN CAP1 CAP1 STK11IP STK11IP MNDA MNDA CPPED1 CPPED1 LOC105814876 LOC105814876 FABP5 FABP5 PADI2 PADI2 DPP7 DPP7 FUCA1 FUCA1 PRSS57 PRSS57 HEBP2 HEBP2 PA2G4 PA2G4 CTSG CTSG GNS GNS ARSA ARSA CREG1 CREG1 FRK FRK GALNS GALNS FAF2 FAF2 IMPDH1 IMPDH1 C3 C3 PRDX6 PRDX6 ENSPCOP00000014061 ENSPCOP00000014061 MAN2B1 MAN2B1 NHLRC3 NHLRC3 DNAJC3 DNAJC3 VAT1 VAT1 MPO MPO BPI BPI GM2A GM2A TTR TTR PYGB PYGB TXNDC5 TXNDC5 GLB1 GLB1 GLA GLA CTSA CTSA GGH GGH ARSB ARSB PLAC8 PLAC8 RETN RETN ACLY ACLY ARG1 ARG1 NAPRT NAPRT ELANE ELANE PRKCD PRKCD FUCA2 FUCA2 TOLLIP TOLLIP AGA AGA TRAPPC1 TRAPPC1 MAPK1 MAPK1 ARHGAP45 ARHGAP45 IST1 IST1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GUSBBeta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (650 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
GRNGranulin precursor. (591 aa)
CAP1Adenylyl cyclase-associated protein; Belongs to the CAP family. (474 aa)
STK11IPSerine/threonine kinase 11 interacting protein. (939 aa)
MNDAMyeloid cell nuclear differentiation antigen. (395 aa)
CPPED1Calcineurin like phosphoesterase domain containing 1. (313 aa)
LOC105814876SERPIN domain-containing protein; Belongs to the serpin family. (218 aa)
FABP5Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
PADI2Peptidyl arginine deiminase 2. (614 aa)
DPP7Dipeptidyl peptidase 7. (489 aa)
FUCA1Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (418 aa)
PRSS57Serine protease 57; Belongs to the peptidase S1 family. (283 aa)
HEBP2Heme binding protein 2. (205 aa)
PA2G4Proliferation-associated 2G4. (394 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (246 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (533 aa)
ARSAArylsulfatase A. (423 aa)
CREG1Cellular repressor of E1A stimulated genes 1. (177 aa)
FRKTyrosine-protein kinase. (508 aa)
GALNSGalactosamine (N-acetyl)-6-sulfatase. (517 aa)
FAF2Fas associated factor family member 2. (448 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (629 aa)
C3Complement C3. (1551 aa)
PRDX6Peroxiredoxin 6. (224 aa)
ENSPCOP00000014061Peptidase S1 domain-containing protein. (113 aa)
MAN2B1Alpha-mannosidase. (1010 aa)
NHLRC3NHL repeat containing 3. (347 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
VAT1Vesicle amine transport 1. (391 aa)
MPOMyeloperoxidase. (742 aa)
BPIBactericidal permeability increasing protein. (487 aa)
GM2AGM2 ganglioside activator. (196 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
TXNDC5Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (423 aa)
GLB1Beta-galactosidase. (640 aa)
GLAAlpha-galactosidase. (428 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (494 aa)
GGHFolate gamma-glutamyl hydrolase. (318 aa)
ARSBArylsulfatase B. (531 aa)
PLAC8Uncharacterized protein. (58 aa)
RETNResistin. (85 aa)
ACLYATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1110 aa)
ARG1Arginase. (229 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (538 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (268 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
FUCA2Alpha-L-fucosidase 2. (391 aa)
TOLLIPToll interacting protein. (275 aa)
AGAAspartylglucosaminidase. (346 aa)
TRAPPC1Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (145 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
ARHGAP45Rho GTPase activating protein 45. (1151 aa)
IST1IST1 factor associated with ESCRT-III. (367 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.