STRINGSTRING
ENSPCOP00000013862 ENSPCOP00000013862 TNFRSF1B TNFRSF1B OLR1 OLR1 TREM2 TREM2 STOML2 STOML2 SLC38A9 SLC38A9 ADCY8 ADCY8 CBL CBL FURIN FURIN LAT2 LAT2 CD36 CD36 CLN3 CLN3 SERPINH1 SERPINH1 NOS3 NOS3 GPM6B GPM6B LCK LCK DLC1 DLC1 CD4 CD4 NTSR1 NTSR1 TEK TEK FYN FYN CDH1 CDH1 MAPK3 MAPK3 CD226 CD226 PLPP1 PLPP1 ARID3C ARID3C RTN4RL2 RTN4RL2 SLC1A2 SLC1A2 CORO1C CORO1C FLOT2 FLOT2 RANGRF RANGRF SELE SELE PLPP3 PLPP3 LAMTOR2 LAMTOR2 LRP4 LRP4 RFTN1 RFTN1 TDGF1 TDGF1 ADAM17 ADAM17 MAPK1 MAPK1 TPP1 TPP1 HYAL2 HYAL2 LRRK2 LRRK2 LYN LYN CAV1 CAV1 SLC6A4 SLC6A4 KCNMA1 KCNMA1 LRP8 LRP8 HDAC6 HDAC6 BTK BTK GP6 GP6 CLN6 CLN6 S1PR1 S1PR1 TNFRSF1A TNFRSF1A MS4A15 MS4A15 FXYD1 FXYD1 LAMTOR4 LAMTOR4 LOC105822932 LOC105822932 CAV2 CAV2 GHSR GHSR LAMTOR3 LAMTOR3 LAMTOR5 LAMTOR5 ITGB2 ITGB2 ABCA1 ABCA1 CD8A CD8A STIM1 STIM1 SLC9A1 SLC9A1 BVES BVES PTCH1 PTCH1 ORAI1 ORAI1 PTGIS PTGIS ANGPT1 ANGPT1 RIT2 RIT2 TRPM8 TRPM8 PPP2R1B PPP2R1B SKAP1 SKAP1 CBLC CBLC PIKFYVE PIKFYVE MAL2 MAL2 SRC SRC CAVIN1 CAVIN1 ENSPCOP00000018033 ENSPCOP00000018033 ITLN1 ITLN1 ABCG2 ABCG2 LOC105811813 LOC105811813 MYO1C MYO1C ARID3A ARID3A ENSPCOP00000015683 ENSPCOP00000015683 CARD11 CARD11 TNF TNF LAMTOR1 LAMTOR1 ENSPCOP00000014320 ENSPCOP00000014320 MLC1 MLC1 ATP2B4 ATP2B4 EMP2 EMP2 PI4K2A PI4K2A ENSPCOP00000000471 ENSPCOP00000000471 CTSD CTSD EZR EZR ASAH2 ASAH2 ENSPCOP00000001002 ENSPCOP00000001002 RFTN2 RFTN2 PPP2CA PPP2CA ENSPCOP00000025379 ENSPCOP00000025379 CD177 CD177 CD48 CD48 PAG1 PAG1 MYOF MYOF SORBS1 SORBS1 ADTRP ADTRP STOM STOM EHD2 EHD2 PPT1 PPT1 CAVIN3 CAVIN3 CDH13 CDH13 LOC105810001 LOC105810001 SELPLG SELPLG CAV3 CAV3 DLL1 DLL1 GPC1 GPC1 KDR KDR PLPP2 PLPP2 FAIM2 FAIM2 FLOT1 FLOT1 CAVIN2 CAVIN2 SCARB1 SCARB1 SCN5A SCN5A CLIP3 CLIP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000013862SER_THR_PHOSPHATASE domain-containing protein. (209 aa)
TNFRSF1BTNF receptor superfamily member 1B. (449 aa)
OLR1Oxidized low density lipoprotein receptor 1. (274 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (224 aa)
STOML2Stomatin like 2. (361 aa)
SLC38A9Solute carrier family 38 member 9. (495 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1229 aa)
CBLCbl proto-oncogene. (891 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (798 aa)
LAT2Linker for activation of T cells family member 2. (233 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
CLN3Battenin. (438 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
NOS3Nitric oxide synthase 3. (994 aa)
GPM6BGlycoprotein M6B. (328 aa)
LCKTyrosine-protein kinase. (417 aa)
DLC1DLC1 Rho GTPase activating protein. (1125 aa)
CD4CD4 molecule. (452 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (402 aa)
TEKTEK receptor tyrosine kinase. (1125 aa)
FYNTyrosine-protein kinase. (537 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CD226CD226 molecule. (335 aa)
PLPP1Phospholipid phosphatase 1. (286 aa)
ARID3CAT-rich interaction domain 3C. (412 aa)
RTN4RL2Reticulon 4 receptor like 2. (420 aa)
SLC1A2Amino acid transporter. (574 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (525 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
SELESelectin E. (610 aa)
PLPP3acidPPc domain-containing protein. (312 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
LRP4LDL receptor related protein 4. (1922 aa)
RFTN1Raftlin, lipid raft linker 1. (578 aa)
TDGF1Teratocarcinoma-derived growth factor 1. (186 aa)
ADAM17ADAM metallopeptidase domain 17. (757 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
TPP1Tripeptidyl peptidase 1. (563 aa)
HYAL2Hyaluronidase. (473 aa)
LRRK2Leucine rich repeat kinase 2. (2427 aa)
LYNTyrosine-protein kinase. (512 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
LRP8LDL receptor related protein 8. (956 aa)
HDAC6Histone deacetylase 6. (1203 aa)
BTKTyrosine-protein kinase. (647 aa)
GP6IG domain-containing protein. (287 aa)
CLN6CLN6 transmembrane ER protein. (296 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
MS4A15Membrane spanning 4-domains A15. (241 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
LOC105822932Uncharacterized protein. (91 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (364 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
LAMTOR5Uncharacterized protein. (149 aa)
ITGB2Integrin beta. (764 aa)
ABCA1ATP binding cassette subfamily A member 1. (2240 aa)
CD8ACD8a molecule. (239 aa)
STIM1Stromal interaction molecule 1. (784 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
BVESBlood vessel epicardial substance. (360 aa)
PTCH1Patched 1. (1449 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (307 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
ANGPT1Angiopoietin 1. (408 aa)
RIT2Ras like without CAAX 2. (164 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (552 aa)
SKAP1Src kinase associated phosphoprotein 1. (358 aa)
CBLCCbl proto-oncogene C. (458 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2053 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (176 aa)
SRCTyrosine-protein kinase. (543 aa)
CAVIN1Caveolae associated protein 1. (389 aa)
ENSPCOP00000018033HH_signal domain-containing protein. (110 aa)
ITLN1Intelectin 1. (328 aa)
ABCG2ABC transporter domain-containing protein. (658 aa)
LOC105811813Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (182 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
ARID3AAT-rich interaction domain 3A. (605 aa)
ENSPCOP00000015683Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (174 aa)
CARD11Caspase recruitment domain family member 11. (1125 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (235 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
ENSPCOP00000014320Uncharacterized protein. (415 aa)
MLC1Modulator of VRAC current 1. (378 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (474 aa)
ENSPCOP00000000471Uncharacterized protein. (96 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (408 aa)
EZREzrin. (586 aa)
ASAH2Neutral ceramidase. (726 aa)
ENSPCOP00000001002Uncharacterized protein. (68 aa)
RFTN2Raftlin family member 2. (468 aa)
PPP2CASerine/threonine-protein phosphatase. (295 aa)
ENSPCOP00000025379Uncharacterized protein. (532 aa)
CD177CD177 molecule. (439 aa)
CD48CD48 molecule. (245 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (426 aa)
MYOFMyoferlin. (2061 aa)
SORBS1Sorbin and SH3 domain containing 1. (1294 aa)
ADTRPAndrogen dependent TFPI regulating protein. (237 aa)
STOMStomatin. (288 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
PPT1Palmitoyl-protein thioesterase 1. (302 aa)
CAVIN3Caveolae associated protein 3. (286 aa)
CDH13Cadherin 13. (713 aa)
LOC105810001Uncharacterized protein. (236 aa)
SELPLGUncharacterized protein. (386 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PLPP2Phospholipid phosphatase 2. (304 aa)
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (316 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
CAVIN2Uncharacterized protein. (424 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (461 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
CLIP3CAP-Gly domain containing linker protein 3. (548 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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