STRINGSTRING
UNC5CL UNC5CL ENSPCOP00000000292 ENSPCOP00000000292 FAS FAS THOC1 THOC1 UNC5B UNC5B LRRD1 LRRD1 NFKB1 NFKB1 DAPK1 DAPK1 ANK1 ANK1 UNC5D UNC5D TNFRSF25 TNFRSF25 NGFR NGFR DTHD1 DTHD1 ANK3 ANK3 ANK2 ANK2 TRADD TRADD ANKDD1B ANKDD1B TNFRSF21 TNFRSF21 ANKDD1A ANKDD1A IRAK2 IRAK2 IRAK3 IRAK3 FADD FADD RIPK1 RIPK1 EDARADD EDARADD NFKB2 NFKB2 CRADD CRADD UNC5A UNC5A TNFRSF1A TNFRSF1A TMDD1 TMDD1 PIDD1 PIDD1 IRAK1 IRAK1 TNFRSF11B TNFRSF11B MYD88 MYD88 UNC5C UNC5C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UNC5CLUnc-5 family C-terminal like. (518 aa)
ENSPCOP00000000292Uncharacterized protein. (404 aa)
FASFas cell surface death receptor. (309 aa)
THOC1THO complex 1. (655 aa)
UNC5BUnc-5 netrin receptor B. (932 aa)
LRRD1Leucine rich repeats and death domain containing 1. (863 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
ANK1Ankyrin 1. (1859 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
TNFRSF25TNF receptor superfamily member 25. (412 aa)
NGFRNerve growth factor receptor. (429 aa)
DTHD1Death domain containing 1. (908 aa)
ANK3Ankyrin 3. (4372 aa)
ANK2Ankyrin 2. (3925 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (528 aa)
TNFRSF21TNF receptor superfamily member 21. (654 aa)
ANKDD1AAnkyrin repeat and death domain containing 1A. (499 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (532 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (505 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
EDARADDEDAR associated death domain. (215 aa)
NFKB2Nuclear factor kappa B subunit 2. (895 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
UNC5AUnc-5 netrin receptor A. (818 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
TMDD1Chromosome 12 open reading frame 81. (310 aa)
PIDD1P53-induced death domain protein 1. (915 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
UNC5CUnc-5 netrin receptor C. (850 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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