20 items (Propithecus coquereli) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

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Your Input:
	RFC1	Replication factor C subunit 1. (1113 aa)
	CTDP1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (971 aa)
	NBN	Nbs1_C domain-containing protein. (429 aa)
	BARD1	BRCA1 associated RING domain 1. (769 aa)
	POLM	DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (491 aa)
	TP53BP1	Tumor protein p53 binding protein 1. (1974 aa)
	PES1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (588 aa)
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	POLL	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (573 aa)
	SLF1	SMC5-SMC6 complex localization factor 1. (1059 aa)
	TOPBP1	DNA topoisomerase II binding protein 1. (1394 aa)
	PARP4	Poly [ADP-ribose] polymerase. (1467 aa)
	PAXIP1	PAX interacting protein 1. (1043 aa)
	ENSPCOP00000023392	Uncharacterized protein. (157 aa)
	XRCC1	X-ray repair cross complementing 1. (598 aa)
	LIG3	DNA ligase. (966 aa)
	TERF2IP	TERF2 interacting protein. (393 aa)
	DNTT	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (511 aa)
	ECT2	Epithelial cell transforming 2. (598 aa)
	ENGASE	Endo-beta-N-acetylglucosaminidase. (729 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BARD1	CTDP1	ENSPCOP00000000639	ENSPCOP00000000502	BRCA1 associated RING domain 1.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.439
BARD1	ENSPCOP00000023392	ENSPCOP00000000639	ENSPCOP00000023392	BRCA1 associated RING domain 1.	Uncharacterized protein.	0.992
BARD1	NBN	ENSPCOP00000000639	ENSPCOP00000000625	BRCA1 associated RING domain 1.	Nbs1_C domain-containing protein.	0.980
BARD1	PARP1	ENSPCOP00000000639	ENSPCOP00000010883	BRCA1 associated RING domain 1.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.536
BARD1	PARP4	ENSPCOP00000000639	ENSPCOP00000021636	BRCA1 associated RING domain 1.	Poly [ADP-ribose] polymerase.	0.446
BARD1	PAXIP1	ENSPCOP00000000639	ENSPCOP00000021813	BRCA1 associated RING domain 1.	PAX interacting protein 1.	0.915
BARD1	PES1	ENSPCOP00000000639	ENSPCOP00000009664	BRCA1 associated RING domain 1.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.	0.574
BARD1	RFC1	ENSPCOP00000000639	ENSPCOP00000027556	BRCA1 associated RING domain 1.	Replication factor C subunit 1.	0.787
BARD1	SLF1	ENSPCOP00000000639	ENSPCOP00000015404	BRCA1 associated RING domain 1.	SMC5-SMC6 complex localization factor 1.	0.998
BARD1	TOPBP1	ENSPCOP00000000639	ENSPCOP00000021540	BRCA1 associated RING domain 1.	DNA topoisomerase II binding protein 1.	0.997
BARD1	TP53BP1	ENSPCOP00000000639	ENSPCOP00000007247	BRCA1 associated RING domain 1.	Tumor protein p53 binding protein 1.	0.928
CTDP1	BARD1	ENSPCOP00000000502	ENSPCOP00000000639	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	BRCA1 associated RING domain 1.	0.439
CTDP1	ENSPCOP00000023392	ENSPCOP00000000502	ENSPCOP00000023392	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Uncharacterized protein.	0.436
DNTT	LIG3	ENSPCOP00000028932	ENSPCOP00000026723	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.	DNA ligase.	0.819
DNTT	PARP1	ENSPCOP00000028932	ENSPCOP00000010883	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.628
DNTT	PARP4	ENSPCOP00000028932	ENSPCOP00000021636	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.	Poly [ADP-ribose] polymerase.	0.574
DNTT	POLL	ENSPCOP00000028932	ENSPCOP00000015178	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.	0.702
DNTT	RFC1	ENSPCOP00000028932	ENSPCOP00000027556	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.	Replication factor C subunit 1.	0.465
DNTT	XRCC1	ENSPCOP00000028932	ENSPCOP00000024972	DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.	X-ray repair cross complementing 1.	0.933
ENSPCOP00000023392	BARD1	ENSPCOP00000023392	ENSPCOP00000000639	Uncharacterized protein.	BRCA1 associated RING domain 1.	0.992