(141 nodes) Small GTPase network (Propithecus coquereli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAP2A	RAP2A, member of RAS oncogene family. (183 aa)
	RAB18	RAB18, member RAS oncogene family. (206 aa)
	CPLANE2	Ciliogenesis and planar polarity effector 2. (258 aa)
	RAB39A	RAB39A, member RAS oncogene family. (217 aa)
	RAB19	RAB19, member RAS oncogene family. (217 aa)
	RAB8B	RAB8B, member RAS oncogene family. (207 aa)
	RAB22A	RAB22A, member RAS oncogene family. (194 aa)
	RAB7B	RAB7B, member RAS oncogene family. (199 aa)
	MRAS	Muscle RAS oncogene homolog. (208 aa)
	RHOU	Ras homolog family member U. (258 aa)
	RAB8A	RAB8A, member RAS oncogene family. (207 aa)
	RAB20	RAB20, member RAS oncogene family. (234 aa)
	ARHGAP5	Rho GTPase activating protein 5. (1501 aa)
	RABL2B	Uncharacterized protein. (229 aa)
	ENSPCOP00000025645	Uncharacterized protein. (162 aa)
	REM2	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
	RHEBL1	RHEB like 1. (183 aa)
	RHOQ	Ras homolog family member Q. (205 aa)
	DIRAS2	DIRAS family GTPase 2. (199 aa)
	DNAJC27	DnaJ heat shock protein family (Hsp40) member C27. (273 aa)
	RND3	Rho family GTPase 3. (244 aa)
	RAB1B	RAB1B, member RAS oncogene family. (201 aa)
	RAB35	RAB35, member RAS oncogene family. (201 aa)
	IFT27	Intraflagellar transport 27. (163 aa)
	DIRAS1	DIRAS family GTPase 1. (198 aa)
	RAB9B	RAB9B, member RAS oncogene family. (201 aa)
	RAB3D	RAB3D, member RAS oncogene family. (219 aa)
	RHOB	Ras homolog family member B. (196 aa)
	RAB25	RAB25, member RAS oncogene family. (213 aa)
	RAC3	Rac family small GTPase 3. (205 aa)
	RASL12	RAS like family 12. (266 aa)
	ENSPCOP00000002268	Uncharacterized protein. (197 aa)
	RHOV	Ras homolog family member V. (236 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (165 aa)
	RAN	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (234 aa)
	RAB42	RAB42, member RAS oncogene family. (218 aa)
	ENSPCOP00000002833	Uncharacterized protein. (145 aa)
	ENSPCOP00000002927	Uncharacterized protein. (160 aa)
	RHOF	Ras homolog family member F, filopodia associated. (211 aa)
	RAB15	RAB15, member RAS oncogene family. (212 aa)
	RASL11A	RAS like family 11 member A. (242 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (183 aa)
	RHOG	Ras homolog family member G. (191 aa)
	RASL10B	RAS like family 10 member B. (203 aa)
	NKIRAS1	NFKB inhibitor interacting Ras like 1. (192 aa)
	ENSPCOP00000030370	Uncharacterized protein. (183 aa)
	ENSPCOP00000030580	Uncharacterized protein. (126 aa)
	RAB11B	RAB11B, member RAS oncogene family. (218 aa)
	RRAD	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
	RAB4B	Uncharacterized protein. (215 aa)
	RAB23	RAB23, member RAS oncogene family. (237 aa)
	RHOD	Ras homolog family member D. (210 aa)
	RAB33A	RAB33A, member RAS oncogene family. (237 aa)
	RAB4A	RAB4A, member RAS oncogene family. (221 aa)
	RAB36	RAB36, member RAS oncogene family. (310 aa)
	RALB	RAS like proto-oncogene B. (212 aa)
	RAB29	RAB29, member RAS oncogene family. (204 aa)
	RIT1	Ras like without CAAX 1. (219 aa)
	RAB44	RAB44, member RAS oncogene family. (978 aa)
	ENSPCOP00000028657	Uncharacterized protein. (79 aa)
	RAB10	RAB10, member RAS oncogene family. (200 aa)
	RAB40B	RAB40B, member RAS oncogene family. (278 aa)
	ENSPCOP00000003740	Uncharacterized protein. (214 aa)
	RAB24	RAB24, member RAS oncogene family. (203 aa)
	RAB27B	RAB27B, member RAS oncogene family. (218 aa)
	RASD2	RASD family member 2. (266 aa)
	RAB13	Uncharacterized protein. (202 aa)
	RAP1B	Uncharacterized protein. (184 aa)
	ENSPCOP00000004448	Uncharacterized protein. (133 aa)
	RAB26	RAB26, member RAS oncogene family. (256 aa)
	RAB39B	RAB39B, member RAS oncogene family. (213 aa)
	RAB5A	RAB5A, member RAS oncogene family. (215 aa)
	RAB7A	RAB7A, member RAS oncogene family. (161 aa)
	RAB3C	RAB3C, member RAS oncogene family. (227 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	RAB3A	RAB3A, member RAS oncogene family. (220 aa)
	ENSPCOP00000005894	Uncharacterized protein. (192 aa)
	RAB33B	RAB33B, member RAS oncogene family. (229 aa)
	RHOA	Ras homolog family member A. (193 aa)
	RHOT1	Uncharacterized protein. (752 aa)
	ENSPCOP00000007709	Uncharacterized protein. (186 aa)
	RAB43	RAB43, member RAS oncogene family. (213 aa)
	RAB28	RAB28, member RAS oncogene family. (221 aa)
	ENSPCOP00000008371	Uncharacterized protein. (101 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (183 aa)
	RAB27A	RAB27A, member RAS oncogene family. (221 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1510 aa)
	LOC105824222	Uncharacterized protein. (216 aa)
	RASL10A	RAS like family 10 member A. (203 aa)
	RHEB	Ras homolog, mTORC1 binding. (184 aa)
	RHOBTB2	Rho related BTB domain containing 2. (727 aa)
	RAC2	Rac family small GTPase 2. (192 aa)
	KRAS	Uncharacterized protein. (75 aa)
	RAB17	RAB17, member RAS oncogene family. (210 aa)
	RAB5B	RAB5B, member RAS oncogene family. (215 aa)
	RAB40C	RAB40C, member RAS oncogene family. (282 aa)
	LOC105807649	Uncharacterized protein. (209 aa)
	NKIRAS2	NFKB inhibitor interacting Ras like 2. (220 aa)
	RRAS2	RAS related 2. (201 aa)
	RHOC	Ras homolog family member C. (193 aa)
	RAB1A	RAB1A, member RAS oncogene family. (207 aa)
	RAB30	RAB30, member RAS oncogene family. (203 aa)
	REM1	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
	RHOJ	Ras homolog family member J. (215 aa)
	RAB14	RAB14, member RAS oncogene family. (215 aa)
	RAB32	RAB32, member RAS oncogene family. (225 aa)
	RRAS	RAS related. (220 aa)
	RALA	RAS like proto-oncogene A. (206 aa)
	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (1073 aa)
	RAB6B	RAB6B, member RAS oncogene family. (208 aa)
	RAB3B	RAB3B, member RAS oncogene family. (219 aa)
	RAB37	RAB37, member RAS oncogene family. (223 aa)
	RASL11B	RAS like family 11 member B. (247 aa)
	RHOBTB1	Rho related BTB domain containing 1. (697 aa)
	RAB12	RAB12, member RAS oncogene family. (244 aa)
	LOC105823285	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (211 aa)
	CRACR2A	Calcium release activated channel regulator 2A. (729 aa)
	RAC1	Rac family small GTPase 1. (211 aa)
	RERG	RAS like estrogen regulated growth inhibitor. (180 aa)
	RHOT2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (621 aa)
	RAB2A	RAB2A, member RAS oncogene family. (212 aa)
	RAB5C	Uncharacterized protein. (216 aa)
	RND2	Rho family GTPase 2. (227 aa)
	RAB38	RAB38, member RAS oncogene family. (211 aa)
	RAB21	RAB21, member RAS oncogene family. (204 aa)
	ENSPCOP00000018169	Uncharacterized protein. (116 aa)
	RND1	Rho family GTPase 1. (232 aa)
	RAB34	RAB34, member RAS oncogene family. (268 aa)
	LOC105826342	Uncharacterized protein. (170 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	ENSPCOP00000019899	Miro domain-containing protein. (554 aa)
	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (907 aa)
	RAB6A	RAB6A, member RAS oncogene family. (208 aa)
	RASD1	Ras related dexamethasone induced 1. (281 aa)
	RAB31	RAB31, member RAS oncogene family. (195 aa)
	RIT2	Ras like without CAAX 2. (164 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1193 aa)
	GEM	GTP binding protein overexpressed in skeletal muscle. (160 aa)
	RASEF	RAS and EF-hand domain containing. (741 aa)
	CDC42	Uncharacterized protein. (191 aa)
	ENSPCOP00000022638	Uncharacterized protein. (159 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP35	CDC42	ENSPCOP00000008940	ENSPCOP00000022305	Rho GTPase activating protein 35.	Uncharacterized protein.	0.730
ARHGAP35	CPLANE2	ENSPCOP00000008940	ENSPCOP00000014599	Rho GTPase activating protein 35.	Ciliogenesis and planar polarity effector 2.	0.490
ARHGAP35	DIRAS1	ENSPCOP00000008940	ENSPCOP00000000371	Rho GTPase activating protein 35.	DIRAS family GTPase 1.	0.545
ARHGAP35	DIRAS2	ENSPCOP00000008940	ENSPCOP00000026549	Rho GTPase activating protein 35.	DIRAS family GTPase 2.	0.545
ARHGAP35	DNAJC27	ENSPCOP00000008940	ENSPCOP00000026554	Rho GTPase activating protein 35.	DnaJ heat shock protein family (Hsp40) member C27.	0.481
ARHGAP35	ENSPCOP00000002833	ENSPCOP00000008940	ENSPCOP00000002833	Rho GTPase activating protein 35.	Uncharacterized protein.	0.515
ARHGAP35	ENSPCOP00000002927	ENSPCOP00000008940	ENSPCOP00000002927	Rho GTPase activating protein 35.	Uncharacterized protein.	0.730
ARHGAP35	ENSPCOP00000005894	ENSPCOP00000008940	ENSPCOP00000005894	Rho GTPase activating protein 35.	Uncharacterized protein.	0.490
ARHGAP35	ENSPCOP00000007709	ENSPCOP00000008940	ENSPCOP00000007709	Rho GTPase activating protein 35.	Uncharacterized protein.	0.481
ARHGAP35	ENSPCOP00000008371	ENSPCOP00000008940	ENSPCOP00000008371	Rho GTPase activating protein 35.	Uncharacterized protein.	0.515
ARHGAP35	ENSPCOP00000019899	ENSPCOP00000008940	ENSPCOP00000019899	Rho GTPase activating protein 35.	Miro domain-containing protein.	0.481
ARHGAP35	ENSPCOP00000025645	ENSPCOP00000008940	ENSPCOP00000025645	Rho GTPase activating protein 35.	Uncharacterized protein.	0.969
ARHGAP35	ENSPCOP00000028657	ENSPCOP00000008940	ENSPCOP00000028657	Rho GTPase activating protein 35.	Uncharacterized protein.	0.481
ARHGAP35	ENSPCOP00000030580	ENSPCOP00000008940	ENSPCOP00000030580	Rho GTPase activating protein 35.	Uncharacterized protein.	0.481
ARHGAP35	GEM	ENSPCOP00000008940	ENSPCOP00000021731	Rho GTPase activating protein 35.	GTP binding protein overexpressed in skeletal muscle.	0.493
ARHGAP35	HRAS	ENSPCOP00000008940	ENSPCOP00000019758	Rho GTPase activating protein 35.	HRas proto-oncogene, GTPase.	0.609
ARHGAP35	KRAS	ENSPCOP00000008940	ENSPCOP00000009614	Rho GTPase activating protein 35.	Uncharacterized protein.	0.609
ARHGAP35	LOC105807649	ENSPCOP00000008940	ENSPCOP00000010174	Rho GTPase activating protein 35.	Uncharacterized protein.	0.515
ARHGAP35	LOC105824222	ENSPCOP00000008940	ENSPCOP00000008960	Rho GTPase activating protein 35.	Uncharacterized protein.	0.515
ARHGAP35	LOC105826342	ENSPCOP00000008940	ENSPCOP00000019543	Rho GTPase activating protein 35.	Uncharacterized protein.	0.556