STRINGSTRING
CRADD CRADD TNFRSF1A TNFRSF1A CARD19 CARD19 BCL10 BCL10 PIDD1 PIDD1 IRAK4 IRAK4 NOD2 NOD2 IRAK1 IRAK1 NLRP6 NLRP6 CASP9 CASP9 TNFRSF11B TNFRSF11B MYD88 MYD88 UNC5C UNC5C NLRP1 NLRP1 MALT1 MALT1 LOC105822171 LOC105822171 PYCARD PYCARD NOD1 NOD1 UNC5CL UNC5CL CARD9 CARD9 BIRC2 BIRC2 DLG5 DLG5 CARD14 CARD14 ENSPCOP00000000292 ENSPCOP00000000292 NLRP11 NLRP11 FAS FAS TTC3 TTC3 NOL3 NOL3 THOC1 THOC1 BIRC3 BIRC3 CFLAR CFLAR MNDA MNDA CARD18 CARD18 ENSPCOP00000005135 ENSPCOP00000005135 UNC5B UNC5B LRRD1 LRRD1 NFKB1 NFKB1 DAPK1 DAPK1 ANK1 ANK1 XIAP XIAP NLRP12 NLRP12 DEDD2 DEDD2 UNC5D UNC5D TNFRSF25 TNFRSF25 NLRP3 NLRP3 MEFV MEFV NGFR NGFR DTHD1 DTHD1 CARD11 CARD11 ANK3 ANK3 CASP2 CASP2 CARD6 CARD6 ANK2 ANK2 TRADD TRADD ANKDD1B ANKDD1B APAF1 APAF1 TNFRSF21 TNFRSF21 ANKDD1A ANKDD1A DEDD DEDD LOC105822166 LOC105822166 IRAK2 IRAK2 CASP10 CASP10 NLRP14 NLRP14 IFIH1 IFIH1 NLRP10 NLRP10 MAVS MAVS IRAK3 IRAK3 EDAR EDAR NLRP5 NLRP5 FADD FADD PEA15 PEA15 CASP8 CASP8 CARD10 CARD10 NLRP2 NLRP2 RIPK1 RIPK1 RIPK2 RIPK2 EDARADD EDARADD NFKB2 NFKB2 UNC5A UNC5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
TNFRSF1ATNF receptor superfamily member 1A. (447 aa)
CARD19Caspase recruitment domain family member 19. (183 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
PIDD1P53-induced death domain protein 1. (915 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (406 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (713 aa)
NLRP6NLR family pyrin domain containing 6. (890 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (406 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
MYD88MYD88 innate immune signal transduction adaptor. (353 aa)
UNC5CUnc-5 netrin receptor C. (850 aa)
NLRP1NLR family pyrin domain containing 1. (1253 aa)
MALT1MALT1 paracaspase. (787 aa)
LOC105822171CARD domain-containing protein. (98 aa)
PYCARDPYD and CARD domain containing. (195 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (949 aa)
UNC5CLUnc-5 family C-terminal like. (518 aa)
CARD9Caspase recruitment domain family member 9. (536 aa)
BIRC2Baculoviral IAP repeat containing 2. (619 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1919 aa)
CARD14Caspase recruitment domain family member 14. (1008 aa)
ENSPCOP00000000292Uncharacterized protein. (404 aa)
NLRP11NLR family pyrin domain containing 11. (1025 aa)
FASFas cell surface death receptor. (309 aa)
TTC3Tetratricopeptide repeat domain 3. (1957 aa)
NOL3Nucleolar protein 3. (204 aa)
THOC1THO complex 1. (655 aa)
BIRC3Baculoviral IAP repeat containing 3. (597 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (333 aa)
MNDAMyeloid cell nuclear differentiation antigen. (395 aa)
CARD18Caspase recruitment domain family member 18. (91 aa)
ENSPCOP00000005135Uncharacterized protein. (183 aa)
UNC5BUnc-5 netrin receptor B. (932 aa)
LRRD1Leucine rich repeats and death domain containing 1. (863 aa)
NFKB1Nuclear factor kappa B subunit 1. (961 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
ANK1Ankyrin 1. (1859 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
NLRP12NLR family pyrin domain containing 12. (941 aa)
DEDD2Death effector domain containing 2. (326 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
TNFRSF25TNF receptor superfamily member 25. (412 aa)
NLRP3NLR family pyrin domain containing 3. (1036 aa)
MEFVMEFV innate immuity regulator, pyrin. (772 aa)
NGFRNerve growth factor receptor. (429 aa)
DTHD1Death domain containing 1. (908 aa)
CARD11Caspase recruitment domain family member 11. (1125 aa)
ANK3Ankyrin 3. (4372 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (452 aa)
CARD6Caspase recruitment domain family member 6. (1038 aa)
ANK2Ankyrin 2. (3925 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (528 aa)
APAF1Apoptotic peptidase activating factor 1. (1204 aa)
TNFRSF21TNF receptor superfamily member 21. (654 aa)
ANKDD1AAnkyrin repeat and death domain containing 1A. (499 aa)
DEDDDeath effector domain containing. (341 aa)
LOC105822166Uncharacterized protein; Belongs to the peptidase C14A family. (285 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (532 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (528 aa)
NLRP14NLR family pyrin domain containing 14. (1091 aa)
IFIH1Interferon induced with helicase C domain 1. (1025 aa)
NLRP10NLR family pyrin domain containing 10. (631 aa)
MAVSMitochondrial antiviral signaling protein. (514 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (505 aa)
EDAREctodysplasin A receptor. (463 aa)
NLRP5Pyrin domain-containing protein. (620 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
PEA15Proliferation and apoptosis adaptor protein 15. (149 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
CARD10Caspase recruitment domain family member 10. (1029 aa)
NLRP2Uncharacterized protein. (915 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
EDARADDEDAR associated death domain. (215 aa)
NFKB2Nuclear factor kappa B subunit 2. (895 aa)
UNC5AUnc-5 netrin receptor A. (818 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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