STRINGSTRING
VWA2 VWA2 CRB2 CRB2 NOTCH4 NOTCH4 CELSR2 CELSR2 SLIT1 SLIT1 DLK1 DLK1 SVEP1 SVEP1 NOTCH2 NOTCH2 DLL1 DLL1 NOTCH1 NOTCH1 NOTCH3 NOTCH3 JAG1 JAG1 SNED1 SNED1 MEGF11 MEGF11 WIF1 WIF1 FBN2 FBN2 SLIT2 SLIT2 FBN3 FBN3 DLL3 DLL3 SLIT3 SLIT3 FAT4 FAT4 JAG2 JAG2 CELSR1 CELSR1 ENSPCOP00000016658 ENSPCOP00000016658 DNER DNER MEGF10 MEGF10 LTBP3 LTBP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWA2Von Willebrand factor A domain containing 2. (756 aa)
CRB2Crumbs cell polarity complex component 2. (1230 aa)
NOTCH4Notch receptor 4. (2000 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2921 aa)
SLIT1Slit guidance ligand 1. (1510 aa)
DLK1Delta like non-canonical Notch ligand 1. (383 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3230 aa)
NOTCH2Notch receptor 2. (2471 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
NOTCH1Notch receptor 1. (2420 aa)
NOTCH3Notch receptor 3. (2318 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1290 aa)
MEGF11Multiple EGF like domains 11. (1033 aa)
WIF1WNT inhibitory factor 1. (382 aa)
FBN2Fibrillin 2. (2912 aa)
SLIT2Slit guidance ligand 2. (1423 aa)
FBN3Fibrillin 3. (2723 aa)
DLL3Delta like canonical Notch ligand 3. (585 aa)
SLIT3Slit guidance ligand 3. (1523 aa)
FAT4FAT atypical cadherin 4. (4954 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1101 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (2924 aa)
ENSPCOP00000016658Uncharacterized protein. (674 aa)
DNERDelta/notch like EGF repeat containing. (622 aa)
MEGF10Multiple EGF like domains 10. (1136 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1306 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.