(28 nodes) Transforming growth factor-beta-related network (Propithecus coquereli)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BMP5	Bone morphogenetic protein 5. (379 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)
	INHBE	Inhibin subunit beta E. (351 aa)
	BMP10	Bone morphogenetic protein 10. (423 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	GDF1	TGF_BETA_2 domain-containing protein. (372 aa)
	GDF10	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
	NODAL	Nodal growth differentiation factor. (348 aa)
	BMP3	Bone morphogenetic protein 3; Belongs to the TGF-beta family. (458 aa)
	INHBB	Inhibin subunit beta B. (408 aa)
	MSTN	Myostatin. (376 aa)
	INHBC	Inhibin subunit beta C. (351 aa)
	GDF15	Growth differentiation factor 15. (310 aa)
	LOC105810406	Left-right determination factor. (364 aa)
	INHA	Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
	GDF9	Growth differentiation factor 9. (452 aa)
	GDF7	Growth differentiation factor 7. (447 aa)
	INHBA	Inhibin subunit beta A. (426 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	GDF11	Growth differentiation factor 11. (404 aa)
	GDF6	Growth differentiation factor 6. (461 aa)
	GDF3	Growth differentiation factor 3. (365 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	BMP6	Bone morphogenetic protein 6. (509 aa)
	GDF2	Growth differentiation factor 2. (427 aa)
	BMP2	Bone morphogenetic protein 2. (395 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP2	ENSPCOP00000006872	ENSPCOP00000030823	Bone morphogenetic protein 10.	Bone morphogenetic protein 2.	0.485
BMP10	BMP4	ENSPCOP00000006872	ENSPCOP00000028335	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.523
BMP10	BMP5	ENSPCOP00000006872	ENSPCOP00000010725	Bone morphogenetic protein 10.	Bone morphogenetic protein 5.	0.537
BMP10	BMP6	ENSPCOP00000006872	ENSPCOP00000028377	Bone morphogenetic protein 10.	Bone morphogenetic protein 6.	0.471
BMP10	BMP7	ENSPCOP00000006872	ENSPCOP00000003744	Bone morphogenetic protein 10.	Bone morphogenetic protein 7.	0.498
BMP10	GDF15	ENSPCOP00000006872	ENSPCOP00000016175	Bone morphogenetic protein 10.	Growth differentiation factor 15.	0.553
BMP10	GDF2	ENSPCOP00000006872	ENSPCOP00000028801	Bone morphogenetic protein 10.	Growth differentiation factor 2.	0.749
BMP10	GDF5	ENSPCOP00000006872	ENSPCOP00000019260	Bone morphogenetic protein 10.	Growth differentiation factor 5.	0.492
BMP10	GDF6	ENSPCOP00000006872	ENSPCOP00000025672	Bone morphogenetic protein 10.	Growth differentiation factor 6.	0.489
BMP10	GDF7	ENSPCOP00000006872	ENSPCOP00000018126	Bone morphogenetic protein 10.	Growth differentiation factor 7.	0.443
BMP2	BMP10	ENSPCOP00000030823	ENSPCOP00000006872	Bone morphogenetic protein 2.	Bone morphogenetic protein 10.	0.485
BMP2	BMP4	ENSPCOP00000030823	ENSPCOP00000028335	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.896
BMP2	BMP5	ENSPCOP00000030823	ENSPCOP00000010725	Bone morphogenetic protein 2.	Bone morphogenetic protein 5.	0.831
BMP2	BMP6	ENSPCOP00000030823	ENSPCOP00000028377	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.936
BMP2	BMP7	ENSPCOP00000030823	ENSPCOP00000003744	Bone morphogenetic protein 2.	Bone morphogenetic protein 7.	0.909
BMP2	GDF2	ENSPCOP00000030823	ENSPCOP00000028801	Bone morphogenetic protein 2.	Growth differentiation factor 2.	0.524
BMP2	GDF5	ENSPCOP00000030823	ENSPCOP00000019260	Bone morphogenetic protein 2.	Growth differentiation factor 5.	0.713
BMP2	GDF6	ENSPCOP00000030823	ENSPCOP00000025672	Bone morphogenetic protein 2.	Growth differentiation factor 6.	0.551
BMP2	GDF7	ENSPCOP00000030823	ENSPCOP00000018126	Bone morphogenetic protein 2.	Growth differentiation factor 7.	0.611
BMP2	NODAL	ENSPCOP00000030823	ENSPCOP00000010056	Bone morphogenetic protein 2.	Nodal growth differentiation factor.	0.649