STRINGSTRING
SH2B3 SH2B3 SOCS6 SOCS6 LYN LYN KIT KIT KITLG KITLG FNDC3B FNDC3B SRC SRC GRB2 GRB2 PTPN6 PTPN6 CBL CBL FNDC3A FNDC3A LCK LCK ENSPCOP00000009588 ENSPCOP00000009588 SOS1 SOS1 FYN FYN SOCS1 SOCS1 LOC105815528 LOC105815528 ENSPCOP00000000722 ENSPCOP00000000722 PRKCA PRKCA LOC105816126 LOC105816126
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SH2B3SH2B adaptor protein 3. (539 aa)
SOCS6Uncharacterized protein. (535 aa)
LYNTyrosine-protein kinase. (512 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
FNDC3BFibronectin type III domain containing 3B. (1156 aa)
SRCTyrosine-protein kinase. (543 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
CBLCbl proto-oncogene. (891 aa)
FNDC3AFibronectin type III domain containing 3A. (1044 aa)
LCKTyrosine-protein kinase. (417 aa)
ENSPCOP00000009588Uncharacterized protein. (316 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
FYNTyrosine-protein kinase. (537 aa)
SOCS1Suppressor of cytokine signaling 1. (223 aa)
LOC105815528Uncharacterized protein. (461 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
PRKCAUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (575 aa)
LOC105816126Suppressor of cytokine signaling 6. (535 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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