STRINGSTRING
ENSPCOP00000017715 ENSPCOP00000017715 CBS CBS MTAP MTAP ENSPCOP00000009939 ENSPCOP00000009939 LOC105813261 LOC105813261 TSTD1 TSTD1 SQOR SQOR ADI1 ADI1 ENOPH1 ENOPH1 TST TST SUOX SUOX CSAD CSAD BHMT BHMT APIP APIP BHMT2 BHMT2 GOT1 GOT1 AHCY AHCY MPST MPST MTR MTR TSTD3 TSTD3 FMO1 FMO1 GOT2 GOT2 CDO1 CDO1 MAT1A MAT1A GADL1 GADL1 ETHE1 ETHE1 ENSPCOP00000022496 ENSPCOP00000022496 TXN2 TXN2 MRI1 MRI1 SLC25A10 SLC25A10
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000017715Flavodoxin-like domain-containing protein. (505 aa)
CBSCystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (554 aa)
MTAPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (299 aa)
ENSPCOP00000009939Uncharacterized protein. (133 aa)
LOC105813261FAD-binding FR-type domain-containing protein. (651 aa)
TSTD1Thiosulfate sulfurtransferase like domain containing 1. (115 aa)
SQORPyr_redox_2 domain-containing protein. (450 aa)
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
ENOPH1Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa)
TSTSulfurtransferase. (297 aa)
SUOXSulfite oxidase. (545 aa)
CSADCysteine sulfinic acid decarboxylase. (493 aa)
BHMTBetaine--homocysteine S-methyltransferase; Involved in the regulation of homocysteine metabolism. (407 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
BHMT2Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa)
GOT1Aspartate aminotransferase. (413 aa)
AHCYAdenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (436 aa)
MPSTMercaptopyruvate sulfurtransferase. (333 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa)
TSTD3Thiosulfate sulfurtransferase like domain containing 3. (112 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
GOT2Aspartate aminotransferase. (370 aa)
CDO1Cysteine dioxygenase. (200 aa)
MAT1AS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa)
GADL1Glutamate decarboxylase like 1. (521 aa)
ETHE1ETHE1 persulfide dioxygenase. (259 aa)
ENSPCOP00000022496Uncharacterized protein. (426 aa)
TXN2Thioredoxin 2. (166 aa)
MRI1Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (325 aa)
SLC25A10Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (287 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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