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| | SIGIRR | Single Ig and TIR domain containing. (410 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (532 aa) |
| | ENSPCOP00000019388 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (151 aa) |
| | PELI2 | Pellino E3 ubiquitin protein ligase family member 2. (386 aa) |
| | ENSPCOP00000019479 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (60 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (505 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (552 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | MEF2A | Myocyte enhancer factor 2A. (495 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (747 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (381 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (826 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | S100A8 | S100 calcium binding protein A8; Belongs to the S-100 family. (89 aa) |
| | TRAF6 | TNF receptor-associated factor. (498 aa) |
| | ELK1 | ETS transcription factor ELK1. (430 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (488 aa) |
| | MAPK9 | Mitogen-activated protein kinase 9. (417 aa) |
| | S100A1 | Protein S100; Belongs to the S-100 family. (139 aa) |
| | LOC105809196 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | ENSPCOP00000002561 | Uncharacterized protein. (546 aa) |
| | ENSPCOP00000002718 | Uncharacterized protein. (210 aa) |
| | LOC105818310 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa) |
| | LOC105820322 | Ubiquitin-like domain-containing protein. (77 aa) |
| | ENSPCOP00000003656 | Uncharacterized protein. (213 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (223 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase A5. (643 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1381 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa) |
| | HMGB1 | Uncharacterized protein. (187 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (397 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (553 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | VRK3 | VRK serine/threonine kinase 3. (453 aa) |
| | KHNYN | KH and NYN domain containing. (666 aa) |
| | LRRC34 | Uncharacterized protein. (211 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | LOC105818311 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (120 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) |
| | FGB | Fibrinogen beta chain. (492 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (961 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (496 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (483 aa) |
| | LOC105819868 | Protein kinase domain-containing protein. (302 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | FNBP4 | Formin binding protein 4. (870 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1217 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1508 aa) |
| | S100A12 | Protein S100; Belongs to the S-100 family. (92 aa) |
| | CD36 | CD36 molecule; Belongs to the CD36 family. (472 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (220 aa) |
| | NFKBIB | NFKB inhibitor beta. (346 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | NLRX1 | NLR family member X1. (975 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (542 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (138 aa) |
| | APP | Amyloid beta precursor protein. (772 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (710 aa) |
| | ENSPCOP00000012718 | Ubiquitin-like domain-containing protein. (74 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1812 aa) |
| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa) |
| | TLR1 | Toll-like receptor. (774 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (745 aa) |
| | S100B | Protein S100; Belongs to the S-100 family. (92 aa) |
| | FGG | Fibrinogen gamma chain. (456 aa) |
| | ENSPCOP00000013862 | SER_THR_PHOSPHATASE domain-containing protein. (209 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (443 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) |
| | S100A9 | S100 calcium binding protein A9; Belongs to the S-100 family. (154 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (432 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (802 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1. (377 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (469 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (906 aa) |
| | RPS27A | Ribosomal protein S27a. (156 aa) |
| | ENSPCOP00000017161 | Mitogen-activated protein kinase kinase kinase 8. (119 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (655 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14. (340 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (609 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (722 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (598 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (280 aa) |
| | ENSPCOP00000018904 | Ubiquitin-like domain-containing protein. (131 aa) |
| | LOC105814628 | HMG box domain-containing protein. (187 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (557 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (473 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | ENSPCOP00000022199 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (282 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (508 aa) |
| | TIRAP | TIR domain containing adaptor protein. (198 aa) |
| | ENSPCOP00000023542 | Ubiquitin-like domain-containing protein. (112 aa) |
| | LOC105818450 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | FGA | Fib_alpha domain-containing protein. (649 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (395 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (895 aa) |
| | ALPK1 | Alpha kinase 1. (1234 aa) |
| | ECSIT | ECSIT signalling integrator. (401 aa) |
| | CCDC71L | Uncharacterized protein. (274 aa) |
| | ENSPCOP00000025404 | Uncharacterized protein. (202 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (295 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (345 aa) |
| | MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa) |
| | LOC105820073 | WRNPLPNID domain-containing protein. (958 aa) |
| | LOC105824228 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa) |
| | ATF1 | Activating transcription factor 1. (270 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (492 aa) |
| | ENSPCOP00000026416 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (158 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (490 aa) |
| | N4BP1 | NEDD4 binding protein 1. (896 aa) |
| | LOC105816759 | Ubiquitin-like domain-containing protein. (156 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (420 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa) |
| | MAPK8 | Mitogen-activated protein kinase 8. (346 aa) |
| | LOC105823889 | Uncharacterized protein. (214 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (406 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1040 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (713 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (890 aa) |
| | BTK | Tyrosine-protein kinase. (647 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (682 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | MYD88 | MYD88 innate immune signal transduction adaptor. (353 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (949 aa) |
| | ENSPCOP00000031440 | annotation not available (119 aa) |
| | MAP2K4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | ENSPCOP00000031725 | Protein kinase domain-containing protein. (272 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa) |
| | FOSL2 | FOS like 2, AP-1 transcription factor subunit. (326 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) |
