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MOCS1 MOCS1 CCDC30 CCDC30 CBLIF CBLIF PNPO PNPO ZC3HAV1L ZC3HAV1L TIPARP TIPARP BTD BTD PC PC LOC105812956 LOC105812956 ACACA ACACA MMACHC MMACHC PANK2 PANK2 PARP16 PARP16 COASY COASY ALDH1L2 ALDH1L2 MROH6 MROH6 MCCC1 MCCC1 LOC105809017 LOC105809017 NADK2 NADK2 C1QTNF5 C1QTNF5 SLC5A6 SLC5A6 ENSPCOP00000017383 ENSPCOP00000017383 ENSPCOP00000017715 ENSPCOP00000017715 NADSYN1 NADSYN1 ENSPCOP00000017868 ENSPCOP00000017868 ZC3HAV1 ZC3HAV1 CYB5R3 CYB5R3 AIG1 AIG1 NMNAT3 NMNAT3 DCAKD DCAKD SLC25A43 SLC25A43 SLC25A47 SLC25A47 NAMPT NAMPT CD320 CD320 AOX1 AOX1 NAXD NAXD BST1 BST1 LDLRAP1 LDLRAP1 LOC105808743 LOC105808743 ENSPCOP00000020489 ENSPCOP00000020489 NMNAT2 NMNAT2 CDCP2 CDCP2 ENPP1 ENPP1 PCCB PCCB PDZD11 PDZD11 NMRK2 NMRK2 PARP4 PARP4 PTGIS PTGIS LOC105810776 LOC105810776 MACROD1 MACROD1 PARP9 PARP9 ANKRD16 ANKRD16 SLC52A1 SLC52A1 SLC19A2 SLC19A2 GPHN GPHN VNN3 VNN3 FAM162A FAM162A SHMT2 SHMT2 DHFR DHFR TCN2 TCN2 FPGS FPGS RFK RFK FLAD1 FLAD1 MACROD2 MACROD2 PANK1 PANK1 NAPRT NAPRT SLC52A2 SLC52A2 MCCC2 MCCC2 PARP15 PARP15 TCN1 TCN1 MOCS2 MOCS2 NMNAT1 NMNAT1 NEUROD6 NEUROD6 MMAB MMAB NT5E NT5E SLC25A16 SLC25A16 CUBN CUBN VNN1 VNN1 MTHFD2 MTHFD2 LOC105819005 LOC105819005 ENSPCOP00000030058 ENSPCOP00000030058 MINDY2 MINDY2 NFS1 NFS1 MTR MTR SLC19A1 SLC19A1 ENSPCOP00000030451 ENSPCOP00000030451 ACACB ACACB SLC46A1 SLC46A1 LOC105808953 LOC105808953 ENSPCOP00000031189 ENSPCOP00000031189 PARP8 PARP8 SLC25A19 SLC25A19 PARP10 PARP10 ENSPCOP00000000033 ENSPCOP00000000033 LOC105813261 LOC105813261 MTHFD1L MTHFD1L MTHFD1 MTHFD1 ENSPCOP00000001180 ENSPCOP00000001180 LOC105808007 LOC105808007 NUDT12 NUDT12 NAXE NAXE GDAP2 GDAP2 NADK NADK LOC105820977 LOC105820977 SHMT1 SHMT1 PANK4 PANK4 SLC2A1 SLC2A1 THTPA THTPA PARP14 PARP14 LRP2 LRP2 MOCOS MOCOS ADTRP ADTRP NMRK1 NMRK1 SLC23A1 SLC23A1 ENSPCOP00000003611 ENSPCOP00000003611 ENSPCOP00000003708 ENSPCOP00000003708 SLC52A3 SLC52A3 CD38 CD38 MTHFD2L MTHFD2L SLC22A13 SLC22A13 TPK1 TPK1 MMUT MMUT ACP5 ACP5 ABCC1 ABCC1 ABCD4 ABCD4 LMBRD1 LMBRD1 VNN2 VNN2 RNLS RNLS AASDHPPT AASDHPPT ENSPCOP00000006387 ENSPCOP00000006387 GSTO2 GSTO2 PPCS PPCS ENPP2 ENPP2 CCDC181 CCDC181 LOC105819061 LOC105819061 MMADHC MMADHC PCCA PCCA ALDH1L1 ALDH1L1 MTHFS MTHFS PDXK PDXK PANK3 PANK3 QPRT QPRT MMAA MMAA PTGS2 PTGS2 SLC5A8 SLC5A8 FASN FASN ENSPCOP00000010431 ENSPCOP00000010431 PARP6 PARP6 AMN AMN OVCA2 OVCA2 MTHFR MTHFR PPCDC PPCDC SLC23A2 SLC23A2 ENPP3 ENPP3 HLCS HLCS
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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MOCS1Molybdenum cofactor synthesis 1. (635 aa)
CCDC30Coiled-coil domain containing 30. (714 aa)
CBLIFCobalamin binding intrinsic factor. (417 aa)
PNPOPyridoxamine 5'-phosphate oxidase. (260 aa)
ZC3HAV1LZinc finger CCCH-type containing, antiviral 1 like. (303 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (658 aa)
BTDBiotinidase. (547 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1178 aa)
LOC105812956Uncharacterized protein. (288 aa)
ACACAAcetyl-CoA carboxylase alpha. (2347 aa)
MMACHCMetabolism of cobalamin associated C. (282 aa)
PANK2Pantothenate kinase 2. (551 aa)
PARP16Poly [ADP-ribose] polymerase. (323 aa)
COASYCTP_transf_like domain-containing protein. (564 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the N-terminal section; belongs to the GART family. (875 aa)
MROH6Maestro heat like repeat family member 6. (708 aa)
MCCC1Methylcrotonoyl-CoA carboxylase 1. (725 aa)
LOC105809017Uncharacterized protein. (603 aa)
NADK2NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (426 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
SLC5A6Solute carrier family 5 member 6; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (633 aa)
ENSPCOP00000017383DHFR domain-containing protein. (165 aa)
ENSPCOP00000017715Flavodoxin-like domain-containing protein. (505 aa)
NADSYN1Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (705 aa)
ENSPCOP00000017868Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (146 aa)
ZC3HAV1Zinc finger CCCH-type containing, antiviral 1. (889 aa)
CYB5R3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (320 aa)
AIG1Androgen induced 1. (238 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (252 aa)
DCAKDDephospho-CoA kinase domain containing. (231 aa)
SLC25A43Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family. (341 aa)
SLC25A47Solute carrier family 25 member 47; Belongs to the mitochondrial carrier (TC 2.A.29) family. (303 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
CD320CD320 molecule. (259 aa)
AOX1Aldehyde oxidase 1. (1303 aa)
NAXDATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. (237 aa)
BST1Bone marrow stromal cell antigen 1. (329 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
LOC105808743Solute carrier family 19 member 3. (431 aa)
ENSPCOP00000020489Uncharacterized protein; Belongs to the 5'-nucleotidase family. (584 aa)
NMNAT2Nicotinamide nucleotide adenylyltransferase 2. (307 aa)
CDCP2CUB domain containing protein 2. (540 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (925 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (554 aa)
PDZD11PDZ domain containing 11. (140 aa)
NMRK2Nicotinamide riboside kinase 2. (230 aa)
PARP4Poly [ADP-ribose] polymerase. (1467 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
LOC105810776MINDY_DUB domain-containing protein. (276 aa)
MACROD1Mono-ADP ribosylhydrolase 1. (325 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (857 aa)
ANKRD16Ankyrin repeat domain 16. (336 aa)
SLC52A1Solute carrier family 52 member 1. (445 aa)
SLC19A2Solute carrier family 19 member 2. (497 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (752 aa)
VNN3Vanin 3. (274 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
DHFRDHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa)
TCN2Transcobalamin 2. (428 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (587 aa)
RFKRiboflavin kinase. (155 aa)
FLAD1FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (490 aa)
MACROD2Mono-ADP ribosylhydrolase 2. (414 aa)
PANK1Pantothenate kinase 1. (598 aa)
NAPRTNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (538 aa)
SLC52A2Solute carrier family 52 member 2. (447 aa)
MCCC2Methylcrotonoyl-CoA carboxylase 2. (563 aa)
PARP15Poly [ADP-ribose] polymerase. (667 aa)
TCN1Transcobalamin 1. (341 aa)
MOCS2Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. (189 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (280 aa)
NEUROD6Neurogenic differentiation factor. (337 aa)
MMABCorrinoid adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (185 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
SLC25A16Solute carrier family 25 member 16; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
CUBNCubilin. (3566 aa)
VNN1Vanin 1. (514 aa)
MTHFD2Uncharacterized protein. (344 aa)
LOC105819005Uncharacterized protein. (1243 aa)
ENSPCOP00000030058Uncharacterized protein. (55 aa)
MINDY2MINDY lysine 48 deubiquitinase 2. (583 aa)
NFS1Aminotran_5 domain-containing protein. (455 aa)
MTRMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa)
SLC19A1Solute carrier family 19 member 1. (476 aa)
ENSPCOP00000030451Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (289 aa)
ACACBAcetyl-CoA carboxylase beta. (2172 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
LOC105808953DHFR domain-containing protein. (140 aa)
ENSPCOP00000031189Uncharacterized protein. (259 aa)
PARP8Poly [ADP-ribose] polymerase. (784 aa)
SLC25A19Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
PARP10Poly [ADP-ribose] polymerase. (985 aa)
ENSPCOP00000000033Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (101 aa)
LOC105813261FAD-binding FR-type domain-containing protein. (651 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (977 aa)
MTHFD1Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (936 aa)
ENSPCOP00000001180Uncharacterized protein. (493 aa)
LOC105808007Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
NUDT12Nudix hydrolase 12. (461 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
GDAP2Ganglioside induced differentiation associated protein 2. (429 aa)
NADKNAD kinase. (536 aa)
LOC105820977Uncharacterized protein. (48 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (441 aa)
PANK44'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. (784 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (495 aa)
THTPAThiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (230 aa)
PARP14Poly [ADP-ribose] polymerase. (1791 aa)
LRP2LDL receptor related protein 2. (4654 aa)
MOCOSMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (879 aa)
ADTRPAndrogen dependent TFPI regulating protein. (237 aa)
NMRK1Nicotinamide riboside kinase 1. (200 aa)
SLC23A1Solute carrier family 23 member 1. (598 aa)
ENSPCOP00000003611DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (182 aa)
ENSPCOP00000003708Uncharacterized protein. (135 aa)
SLC52A3Solute carrier family 52 member 3. (466 aa)
CD38CD38 molecule. (290 aa)
MTHFD2LUncharacterized protein. (133 aa)
SLC22A13Solute carrier family 22 member 13. (551 aa)
TPK1Thiamin pyrophosphokinase 1. (174 aa)
MMUTMethylmalonyl-CoA mutase. (750 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
ABCC1ATP binding cassette subfamily C member 1. (1504 aa)
ABCD4ATP binding cassette subfamily D member 4. (606 aa)
LMBRD1LMBR1 domain containing 1. (370 aa)
VNN2Vanin 2. (516 aa)
RNLSRenalase, FAD dependent amine oxidase. (342 aa)
AASDHPPTAminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase. (309 aa)
ENSPCOP00000006387Uncharacterized protein. (210 aa)
GSTO2Glutathione S-transferase omega 2; Belongs to the GST superfamily. (243 aa)
PPCSPhosphopantothenoylcysteine synthetase. (311 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (911 aa)
CCDC181Coiled-coil domain containing 181. (336 aa)
LOC105819061Uncharacterized protein. (1343 aa)
MMADHCUncharacterized protein. (267 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (702 aa)
ALDH1L1Aldehyde dehydrogenase 1 family member L1; Belongs to the aldehyde dehydrogenase family. (752 aa)
MTHFSUncharacterized protein. (139 aa)
PDXKPyridoxal kinase. (312 aa)
PANK3Pantothenate kinase 3. (370 aa)
QPRTNicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (295 aa)
MMAAMetabolism of cobalamin associated A. (420 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
SLC5A8Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (524 aa)
FASNFatty acid synthase. (2506 aa)
ENSPCOP00000010431Uncharacterized protein. (362 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
AMNAmnion associated transmembrane protein. (452 aa)
OVCA2OVCA2 serine hydrolase domain containing. (227 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (696 aa)
PPCDCPhosphopantothenoylcysteine decarboxylase. (204 aa)
SLC23A2Solute carrier family 23 member 2. (632 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (777 aa)
HLCSHolocarboxylase synthetase. (727 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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