STRINGSTRING
KAT5 KAT5 LOC105805690 LOC105805690 LOC105805688 LOC105805688 LOC105805701 LOC105805701 ENSPCOP00000000819 ENSPCOP00000000819 LOC105812697 LOC105812697 ENSPCOP00000001292 ENSPCOP00000001292 LOC105805702 LOC105805702 ENSPCOP00000001375 ENSPCOP00000001375 ENSPCOP00000001451 ENSPCOP00000001451 LOC105808155 LOC105808155 LOC105817995 LOC105817995 LOC105805703 LOC105805703 LOC105805676 LOC105805676 LOC105805653 LOC105805653 LOC105805691 LOC105805691 LOC105805686 LOC105805686 LOC105805699 LOC105805699 PYGO1 PYGO1 ENSPCOP00000002776 ENSPCOP00000002776 ENSPCOP00000002858 ENSPCOP00000002858 ENSPCOP00000002972 ENSPCOP00000002972 H2AC6 H2AC6 LOC105821920 LOC105821920 LOC105805647 LOC105805647 ENSPCOP00000003606 ENSPCOP00000003606 MYC MYC ENSPCOP00000003703 ENSPCOP00000003703 H2BC9 H2BC9 LOC105821917 LOC105821917 H2AC20 H2AC20 H2AX H2AX ENSPCOP00000004369 ENSPCOP00000004369 LEF1 LEF1 H2BC15 H2BC15 ENSPCOP00000004787 ENSPCOP00000004787 ENSPCOP00000004829 ENSPCOP00000004829 ENSPCOP00000005069 ENSPCOP00000005069 ENSPCOP00000005384 ENSPCOP00000005384 LOC105805692 LOC105805692 LOC105805726 LOC105805726 LOC105805697 LOC105805697 LOC105805682 LOC105805682 ENSPCOP00000006301 ENSPCOP00000006301 AXIN2 AXIN2 BCL9 BCL9 TCF7L2 TCF7L2 TLE1 TLE1 RBBP5 RBBP5 H2AZ2 H2AZ2 BCL9L BCL9L ENSPCOP00000013418 ENSPCOP00000013418 LOC105807652 LOC105807652 RUVBL1 RUVBL1 LEO1 LEO1 SLC39A13 SLC39A13 MEN1 MEN1 EP300 EP300 TRRAP TRRAP CREBBP CREBBP ENSPCOP00000021297 ENSPCOP00000021297 H3F3B H3F3B CDC73 CDC73 SMARCA4 SMARCA4 KMT2D KMT2D H2BC5 H2BC5 TLE3 TLE3 ENSPCOP00000022568 ENSPCOP00000022568 CTNNB1 CTNNB1 TLE4 TLE4 RUNX3 RUNX3 ASH2L ASH2L HDAC1 HDAC1 ENSPCOP00000025432 ENSPCOP00000025432 PYGO2 PYGO2 LOC105824205 LOC105824205 H2AJ H2AJ LOC105816693 LOC105816693 LOC105805725 LOC105805725 H3F3C H3F3C H3-4 H3-4 LOC105805679 LOC105805679 LOC105805675 LOC105805675 ENSPCOP00000028220 ENSPCOP00000028220 ENSPCOP00000028227 ENSPCOP00000028227 LOC105805698 LOC105805698 ENSPCOP00000028467 ENSPCOP00000028467 H2BC11 H2BC11 H3F3A H3F3A TCF7L1 TCF7L1 TLE6 TLE6 TLE2 TLE2 TCF7 TCF7 LOC105807749 LOC105807749
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
LOC105805690Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105805688Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105805701Histone H3; Belongs to the histone H3 family. (136 aa)
ENSPCOP00000000819annotation not available (136 aa)
LOC105812697Histone H3; Belongs to the histone H3 family. (136 aa)
ENSPCOP00000001292annotation not available (136 aa)
LOC105805702Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSPCOP00000001375annotation not available (136 aa)
ENSPCOP00000001451annotation not available (136 aa)
LOC105808155Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105817995Histone domain-containing protein. (136 aa)
LOC105805703Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105805676Histone H3.1. (136 aa)
LOC105805653Histone H3.1. (136 aa)
LOC105805691Histone H2B; Belongs to the histone H2B family. (132 aa)
LOC105805686Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105805699Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
PYGO1Pygopus family PHD finger 1. (419 aa)
ENSPCOP00000002776Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (330 aa)
ENSPCOP00000002858annotation not available (103 aa)
ENSPCOP00000002972annotation not available (103 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC105821920Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105805647Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSPCOP00000003606annotation not available (136 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
ENSPCOP00000003703annotation not available (103 aa)
H2BC9Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC105821917Histone H3; Belongs to the histone H3 family. (136 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
ENSPCOP00000004369Histone domain-containing protein. (136 aa)
LEF1Lymphoid enhancer binding factor 1. (432 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSPCOP00000004787Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (445 aa)
ENSPCOP00000004829RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (71 aa)
ENSPCOP00000005069annotation not available (103 aa)
ENSPCOP00000005384annotation not available (103 aa)
LOC105805692Histone H2B type 1. (126 aa)
LOC105805726Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
LOC105805697Histone H4. (103 aa)
LOC105805682Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSPCOP00000006301Histone domain-containing protein; Belongs to the histone H2B family. (145 aa)
AXIN2Axin 2. (716 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
TLE1TLE family member 1, transcriptional corepressor. (774 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (552 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (129 aa)
BCL9LBCL9 like. (1497 aa)
ENSPCOP00000013418Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (88 aa)
LOC105807652Histone H2A; Belongs to the histone H2A family. (263 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (245 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (665 aa)
SLC39A13Solute carrier family 39 member 13. (368 aa)
MEN1Menin 1. (616 aa)
EP300E1A binding protein p300. (2424 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3861 aa)
CREBBPCREB binding protein. (2449 aa)
ENSPCOP00000021297Uncharacterized protein; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (76 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
CDC73Cell division cycle 73. (429 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1661 aa)
KMT2DLysine methyltransferase 2D. (5467 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (131 aa)
TLE3TLE family member 3, transcriptional corepressor. (784 aa)
ENSPCOP00000022568Uncharacterized protein; Belongs to the histone H2B family. (103 aa)
CTNNB1Catenin beta 1. (781 aa)
TLE4TLE family member 4, transcriptional corepressor. (796 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (433 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (639 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ENSPCOP00000025432Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (747 aa)
PYGO2Pygopus family PHD finger 2. (407 aa)
LOC105824205Histone H2A; Belongs to the histone H2A family. (112 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
LOC105816693Histone H4. (103 aa)
LOC105805725Histone H3.1. (136 aa)
H3F3CHistone H3; Belongs to the histone H3 family. (136 aa)
H3-4Histone H3; Belongs to the histone H3 family. (136 aa)
LOC105805679Histone H2A type 1. (130 aa)
LOC105805675Histone H3.1. (136 aa)
ENSPCOP00000028220annotation not available (103 aa)
ENSPCOP00000028227annotation not available (103 aa)
LOC105805698Histone H4. (103 aa)
ENSPCOP00000028467Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
H3F3AHistone domain-containing protein. (137 aa)
TCF7L1Transcription factor 7 like 1. (590 aa)
TLE6TLE family member 6, subcortical maternal complex member. (567 aa)
TLE2TLE family member 2, transcriptional corepressor. (737 aa)
TCF7Transcription factor 7. (303 aa)
LOC105807749RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (284 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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