STRINGSTRING
ABI1 ABI1 ENSPCOP00000008182 ENSPCOP00000008182 MAPK3 MAPK3 FYN FYN ENSPCOP00000008610 ENSPCOP00000008610 WIPF1 WIPF1 MYO1D MYO1D SYK SYK LOC105821782 LOC105821782 ENSPCOP00000009948 ENSPCOP00000009948 ACTL8 ACTL8 ENSPCOP00000004318 ENSPCOP00000004318 NF2 NF2 IGKV4-1 IGKV4-1 HCK HCK PLCG2 PLCG2 MYO9B MYO9B DSTN DSTN ARPC4 ARPC4 FMN1 FMN1 ENSPCOP00000013064 ENSPCOP00000013064 ARPC3 ARPC3 MYH9 MYH9 CFL2 CFL2 ENSPCOP00000004655 ENSPCOP00000004655 ACTB ACTB ENSPCOP00000004859 ENSPCOP00000004859 ARPC1A ARPC1A ARPC5L ARPC5L PLD5 PLD5 ENSPCOP00000005941 ENSPCOP00000005941 MYO10 MYO10 WIPF3 WIPF3 ENSPCOP00000006591 ENSPCOP00000006591 HSP90AB1 HSP90AB1 CYFIP1 CYFIP1 PAK1 PAK1 PLA2G6 PLA2G6 MYO1A MYO1A ENSPCOP00000007809 ENSPCOP00000007809 VAV2 VAV2 MYO5C MYO5C FMN2 FMN2 WASF2 WASF2 LOC105822770 LOC105822770 VAV1 VAV1 PIK3CA PIK3CA PLD4 PLD4 MYO1C MYO1C CD247 CD247 WASF3 WASF3 PIK3CB PIK3CB ENSPCOP00000016555 ENSPCOP00000016555 CD3G CD3G LIMK1 LIMK1 BRK1 BRK1 GRB2 GRB2 ENSPCOP00000017807 ENSPCOP00000017807 LOC105812452 LOC105812452 CRK CRK PIK3R2 PIK3R2 FGR FGR PIK3R1 PIK3R1 ENSPCOP00000018566 ENSPCOP00000018566 SRC SRC ITPR3 ITPR3 NCKAP1L NCKAP1L MYO5A MYO5A LOC105811778 LOC105811778 VAV3 VAV3 CFL1 CFL1 ENSPCOP00000021017 ENSPCOP00000021017 ENSPCOP00000021147 ENSPCOP00000021147 BAIAP2 BAIAP2 LOC105823974 LOC105823974 ACTG1 ACTG1 ENSPCOP00000022032 ENSPCOP00000022032 ENSPCOP00000022202 ENSPCOP00000022202 CDC42 CDC42 ARPC5 ARPC5 PLD3 PLD3 ABI2 ABI2 ACTR3 ACTR3 WASL WASL PLCG1 PLCG1 LYN LYN ENSPCOP00000024978 ENSPCOP00000024978 MYO1B MYO1B ITPR1 ITPR1 AHCYL1 AHCYL1 PTK2 PTK2 PRKCE PRKCE PRKCD PRKCD PLPP4 PLPP4 ACTR2 ACTR2 WIPF2 WIPF2 ENSPCOP00000026911 ENSPCOP00000026911 ACTR3B ACTR3B PLD1 PLD1 ENSPCOP00000000440 ENSPCOP00000000440 ENSPCOP00000000722 ENSPCOP00000000722 ENSPCOP00000000994 ENSPCOP00000000994 ENSPCOP00000001046 ENSPCOP00000001046 ENSPCOP00000001258 ENSPCOP00000001258 ENSPCOP00000027946 ENSPCOP00000027946 ELMO3 ELMO3 LOC105812575 LOC105812575 ELMO1 ELMO1 ENSPCOP00000028553 ENSPCOP00000028553 BTK BTK MAPK1 MAPK1 LOC105817025 LOC105817025 PLPP5 PLPP5 HSP90AA1 HSP90AA1 LOC105810942 LOC105810942 ELMO2 ELMO2 CYFIP2 CYFIP2 WAS WAS MYO1G MYO1G PLD2 PLD2 ARPC2 ARPC2 NCK1 NCK1 NCKAP1 NCKAP1 ENSPCOP00000002125 ENSPCOP00000002125 LOC105806099 LOC105806099 ENSPCOP00000002511 ENSPCOP00000002511 NCKIPSD NCKIPSD ENSPCOP00000002927 ENSPCOP00000002927 ENSPCOP00000002988 ENSPCOP00000002988 ENSPCOP00000003391 ENSPCOP00000003391 ARPC1B ARPC1B ITPR2 ITPR2 WASF1 WASF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABI1Abl interactor 1. (508 aa)
ENSPCOP00000008182Ig-like domain-containing protein. (169 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSPCOP00000008610Ig-like domain-containing protein. (158 aa)
WIPF1WH2 domain-containing protein. (509 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1002 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
LOC105821782Uncharacterized protein. (380 aa)
ENSPCOP00000009948Uncharacterized protein. (605 aa)
ACTL8Actin like 8; Belongs to the actin family. (351 aa)
ENSPCOP00000004318Ig-like domain-containing protein. (158 aa)
NF2Neurofibromin 2. (596 aa)
IGKV4-1Immunoglobulin kappa variable 4-1. (136 aa)
HCKTyrosine-protein kinase. (524 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1233 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2159 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (170 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (186 aa)
FMN1Formin 1. (1370 aa)
ENSPCOP00000013064Uncharacterized protein. (97 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1967 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
ENSPCOP00000004655WD_REPEATS_REGION domain-containing protein. (262 aa)
ACTBActin beta. (378 aa)
ENSPCOP00000004859Uncharacterized protein. (132 aa)
ARPC1AUncharacterized protein. (188 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
PLD5Phospholipase D family member 5. (536 aa)
ENSPCOP00000005941Ig-like domain-containing protein. (158 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2080 aa)
WIPF3WAS/WASL interacting protein family member 3. (394 aa)
ENSPCOP00000006591Ig-like domain-containing protein. (158 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (715 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1244 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PLA2G6Phospholipase A2 group VI. (807 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
ENSPCOP00000007809Ig-like domain-containing protein. (158 aa)
VAV2Vav guanine nucleotide exchange factor 2. (771 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1691 aa)
FMN2Formin 2. (1572 aa)
WASF2WASP family member 2. (497 aa)
LOC105822770Ig-like domain-containing protein. (140 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
PLD4Phospholipase D family member 4. (502 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1063 aa)
CD247CD247 molecule. (164 aa)
WASF3WASP family member 3. (485 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ENSPCOP00000016555Ig-like domain-containing protein. (145 aa)
CD3GCD3g molecule. (182 aa)
LIMK1LIM domain kinase 1. (678 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSPCOP00000017807Ig-like domain-containing protein. (178 aa)
LOC105812452HATPase_c domain-containing protein. (680 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PIK3R2Uncharacterized protein. (726 aa)
FGRTyrosine-protein kinase. (495 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSPCOP00000018566Uncharacterized protein. (113 aa)
SRCTyrosine-protein kinase. (543 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
NCKAP1LNCK associated protein 1 like. (1138 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1862 aa)
LOC105811778WD_REPEATS_REGION domain-containing protein. (354 aa)
VAV3Vav guanine nucleotide exchange factor 3. (765 aa)
CFL1ADF-H domain-containing protein. (178 aa)
ENSPCOP00000021017Ig-like domain-containing protein. (153 aa)
ENSPCOP00000021147Ig-like domain-containing protein. (127 aa)
BAIAP2BAI1 associated protein 2. (544 aa)
LOC105823974WH2 domain-containing protein. (464 aa)
ACTG1Actin gamma 1. (404 aa)
ENSPCOP00000022032Ig-like domain-containing protein. (95 aa)
ENSPCOP00000022202Uncharacterized protein. (121 aa)
CDC42Uncharacterized protein. (191 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (126 aa)
PLD3Phospholipase D family member 3. (490 aa)
ABI2Abl interactor 2. (513 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
LYNTyrosine-protein kinase. (512 aa)
ENSPCOP00000024978ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (148 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1139 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PLPP4Phospholipid phosphatase 4. (271 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
WIPF2WAS/WASL interacting protein family member 2. (440 aa)
ENSPCOP00000026911Ig-like domain-containing protein. (149 aa)
ACTR3BUncharacterized protein; Belongs to the actin family. (353 aa)
PLD1Phospholipase. (1040 aa)
ENSPCOP00000000440Ig-like domain-containing protein. (158 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
ENSPCOP00000000994Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
ENSPCOP00000001046Ig-like domain-containing protein. (171 aa)
ENSPCOP00000001258Uncharacterized protein. (136 aa)
ENSPCOP00000027946Uncharacterized protein. (298 aa)
ELMO3Engulfment and cell motility 3. (748 aa)
LOC105812575Phospholipase D4-like. (76 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
ENSPCOP00000028553HATPase_c domain-containing protein. (333 aa)
BTKTyrosine-protein kinase. (647 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
LOC105817025ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (218 aa)
PLPP5Phospholipid phosphatase 5. (262 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (816 aa)
LOC105810942WD_REPEATS_REGION domain-containing protein. (347 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
WASWASP actin nucleation promoting factor. (503 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
PLD2Phospholipase. (932 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (292 aa)
NCK1Cytoplasmic protein. (377 aa)
NCKAP1NCK associated protein 1. (1006 aa)
ENSPCOP00000002125ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (149 aa)
LOC105806099WH2 domain-containing protein. (466 aa)
ENSPCOP00000002511Ig-like domain-containing protein. (158 aa)
NCKIPSDNCK interacting protein with SH3 domain. (714 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
ENSPCOP00000002988Ig-like domain-containing protein. (145 aa)
ENSPCOP00000003391Ig-like domain-containing protein. (148 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
WASF1WASP family member 1. (559 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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