13 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSP90AA1	Heat shock protein 90 alpha family class A member 1. (816 aa)
	DDAH1	Dimethylarginine dimethylaminohydrolase 1. (285 aa)
	RECQL	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (581 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	ENSPCOP00000018566	Uncharacterized protein. (113 aa)
	LYPLA1	Lysophospholipase 1. (229 aa)
	LOC105812452	HATPase_c domain-containing protein. (680 aa)
	DDAH2	Dimethylarginine dimethylaminohydrolase 2. (285 aa)
	NOS3	Nitric oxide synthase 3. (994 aa)
	ZDHHC21	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (247 aa)
	CYGB	Cytoglobin; Belongs to the globin family. (219 aa)
	SPR	Sepiapterin reductase. (261 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	CAV1	ENSPCOP00000028969	ENSPCOP00000025045	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.636
AKT1	ENSPCOP00000018566	ENSPCOP00000028969	ENSPCOP00000018566	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.952
AKT1	HSP90AA1	ENSPCOP00000028969	ENSPCOP00000030840	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Heat shock protein 90 alpha family class A member 1.	0.952
AKT1	LOC105812452	ENSPCOP00000028969	ENSPCOP00000017930	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	HATPase_c domain-containing protein.	0.952
AKT1	NOS3	ENSPCOP00000028969	ENSPCOP00000009840	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Nitric oxide synthase 3.	0.980
AKT1	SPR	ENSPCOP00000028969	ENSPCOP00000002512	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Sepiapterin reductase.	0.715
CAV1	AKT1	ENSPCOP00000025045	ENSPCOP00000028969	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.636
CAV1	ENSPCOP00000018566	ENSPCOP00000025045	ENSPCOP00000018566	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.758
CAV1	HSP90AA1	ENSPCOP00000025045	ENSPCOP00000030840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Heat shock protein 90 alpha family class A member 1.	0.758
CAV1	LOC105812452	ENSPCOP00000025045	ENSPCOP00000017930	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	HATPase_c domain-containing protein.	0.758
CAV1	NOS3	ENSPCOP00000025045	ENSPCOP00000009840	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 3.	0.940
DDAH1	DDAH2	ENSPCOP00000030766	ENSPCOP00000017618	Dimethylarginine dimethylaminohydrolase 1.	Dimethylarginine dimethylaminohydrolase 2.	0.510
DDAH1	NOS3	ENSPCOP00000030766	ENSPCOP00000009840	Dimethylarginine dimethylaminohydrolase 1.	Nitric oxide synthase 3.	0.497
DDAH2	DDAH1	ENSPCOP00000017618	ENSPCOP00000030766	Dimethylarginine dimethylaminohydrolase 2.	Dimethylarginine dimethylaminohydrolase 1.	0.510
DDAH2	NOS3	ENSPCOP00000017618	ENSPCOP00000009840	Dimethylarginine dimethylaminohydrolase 2.	Nitric oxide synthase 3.	0.414
ENSPCOP00000018566	AKT1	ENSPCOP00000018566	ENSPCOP00000028969	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.952
ENSPCOP00000018566	CAV1	ENSPCOP00000018566	ENSPCOP00000025045	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.758
ENSPCOP00000018566	NOS3	ENSPCOP00000018566	ENSPCOP00000009840	Uncharacterized protein.	Nitric oxide synthase 3.	0.933
ENSPCOP00000018566	SPR	ENSPCOP00000018566	ENSPCOP00000002512	Uncharacterized protein.	Sepiapterin reductase.	0.643
HSP90AA1	AKT1	ENSPCOP00000030840	ENSPCOP00000028969	Heat shock protein 90 alpha family class A member 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.952