22 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	SHC1	SHC adaptor protein 1. (582 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	ANGPT1	Angiopoietin 1. (408 aa)
	DOK2	Docking protein 2. (409 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	PIK3R2	Uncharacterized protein. (726 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	ANGPT2	Angiopoietin 2. (496 aa)
	TIE1	Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa)
	GRB14	Growth factor receptor bound protein 14. (476 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	PIK3CA	Phosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
	CSDE1	Cold shock domain containing E1. (798 aa)
	ANGPT4	Angiopoietin 4. (499 aa)
	KRAS	Uncharacterized protein. (75 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	ANGPTL7	Angiopoietin like 7. (344 aa)
	ENSPCOP00000002686	CSD_1 domain-containing protein. (293 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	GRB7	Growth factor receptor bound protein 7. (531 aa)
	TEK	TEK receptor tyrosine kinase. (1125 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPT1	ANGPT2	ENSPCOP00000021737	ENSPCOP00000017642	Angiopoietin 1.	Angiopoietin 2.	0.883
ANGPT1	ANGPT4	ENSPCOP00000021737	ENSPCOP00000010084	Angiopoietin 1.	Angiopoietin 4.	0.861
ANGPT1	DOK2	ENSPCOP00000021737	ENSPCOP00000018574	Angiopoietin 1.	Docking protein 2.	0.538
ANGPT1	GRB14	ENSPCOP00000021737	ENSPCOP00000017484	Angiopoietin 1.	Growth factor receptor bound protein 14.	0.467
ANGPT1	GRB2	ENSPCOP00000021737	ENSPCOP00000017791	Angiopoietin 1.	Growth factor receptor bound protein 2.	0.477
ANGPT1	PIK3CA	ENSPCOP00000021737	ENSPCOP00000015588	Angiopoietin 1.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.541
ANGPT1	PIK3CB	ENSPCOP00000021737	ENSPCOP00000016466	Angiopoietin 1.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.517
ANGPT1	PIK3R1	ENSPCOP00000021737	ENSPCOP00000018534	Angiopoietin 1.	Phosphoinositide-3-kinase regulatory subunit 1.	0.479
ANGPT1	PIK3R2	ENSPCOP00000021737	ENSPCOP00000018359	Angiopoietin 1.	Uncharacterized protein.	0.568
ANGPT1	PTPN11	ENSPCOP00000021737	ENSPCOP00000029437	Angiopoietin 1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.552
ANGPT1	TEK	ENSPCOP00000021737	ENSPCOP00000008595	Angiopoietin 1.	TEK receptor tyrosine kinase.	0.995
ANGPT1	TIE1	ENSPCOP00000021737	ENSPCOP00000017546	Angiopoietin 1.	Tyrosine kinase with immunoglobulin like and EGF like domains 1.	0.950
ANGPT2	ANGPT1	ENSPCOP00000017642	ENSPCOP00000021737	Angiopoietin 2.	Angiopoietin 1.	0.883
ANGPT2	ANGPT4	ENSPCOP00000017642	ENSPCOP00000010084	Angiopoietin 2.	Angiopoietin 4.	0.883
ANGPT2	GRB14	ENSPCOP00000017642	ENSPCOP00000017484	Angiopoietin 2.	Growth factor receptor bound protein 14.	0.417
ANGPT2	GRB2	ENSPCOP00000017642	ENSPCOP00000017791	Angiopoietin 2.	Growth factor receptor bound protein 2.	0.445
ANGPT2	PIK3CA	ENSPCOP00000017642	ENSPCOP00000015588	Angiopoietin 2.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.413
ANGPT2	PIK3CB	ENSPCOP00000017642	ENSPCOP00000016466	Angiopoietin 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.413
ANGPT2	PIK3R1	ENSPCOP00000017642	ENSPCOP00000018534	Angiopoietin 2.	Phosphoinositide-3-kinase regulatory subunit 1.	0.416
ANGPT2	PIK3R2	ENSPCOP00000017642	ENSPCOP00000018359	Angiopoietin 2.	Uncharacterized protein.	0.416