STRINGSTRING
SLIT3 SLIT3 NTN1 NTN1 UNC5B UNC5B PAK1 PAK1 RGMB RGMB FYN FYN LOC105819868 LOC105819868 UNC5D UNC5D SIAH1 SIAH1 MYO10 MYO10 NTN4 NTN4 SIAH2 SIAH2 ABLIM3 ABLIM3 HJV HJV SRC SRC DSCAML1 DSCAML1 MAPK14 MAPK14 RGMA RGMA MAPK11 MAPK11 MAPK12 MAPK12 AGAP1 AGAP1 SLIT2 SLIT2 TRPC7 TRPC7 TRPC4 TRPC4 NEO1 NEO1 TRPC5 TRPC5 DSCAM DSCAM ENSPCOP00000010769 ENSPCOP00000010769 SLIT1 SLIT1 UNC5C UNC5C MAPK13 MAPK13 ABLIM2 ABLIM2 PTPN11 PTPN11 MAPK8 MAPK8 ENSPCOP00000028080 ENSPCOP00000028080 PRKCQ PRKCQ PTK2 PTK2 UNC5A UNC5A ROBO1 ROBO1 TRPC1 TRPC1 ENSPCOP00000002927 ENSPCOP00000002927 NCK1 NCK1 EZR EZR PLCG1 PLCG1 WASL WASL IGDCC4 IGDCC4 TRPC6 TRPC6 CDC42 CDC42 MAPK10 MAPK10 AGAP2 AGAP2 TRIO TRIO ABLIM1 ABLIM1 TRPC3 TRPC3 AGAP3 AGAP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLIT3Slit guidance ligand 3. (1523 aa)
NTN1Netrin 1. (604 aa)
UNC5BUnc-5 netrin receptor B. (932 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (481 aa)
FYNTyrosine-protein kinase. (537 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
UNC5DUnc-5 netrin receptor D. (958 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (312 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2080 aa)
NTN4Netrin 4. (628 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
ABLIM3Actin binding LIM protein family member 3. (636 aa)
HJVHemojuvelin BMP co-receptor. (313 aa)
SRCTyrosine-protein kinase. (543 aa)
DSCAML1DS cell adhesion molecule like 1. (1882 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (451 aa)
MAPK11Mitogen-activated protein kinase. (443 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
AGAP1ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (1073 aa)
SLIT2Slit guidance ligand 2. (1423 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
NEO1Neogenin 1. (1443 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
DSCAMDS cell adhesion molecule. (1917 aa)
ENSPCOP00000010769Ig-like domain-containing protein. (119 aa)
SLIT1Slit guidance ligand 1. (1510 aa)
UNC5CUnc-5 netrin receptor C. (850 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ABLIM2Actin binding LIM protein family member 2. (645 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
MAPK8Mitogen-activated protein kinase 8. (346 aa)
ENSPCOP00000028080Uncharacterized protein. (597 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
UNC5AUnc-5 netrin receptor A. (818 aa)
ROBO1Uncharacterized protein. (1334 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
NCK1Cytoplasmic protein. (377 aa)
EZREzrin. (586 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1304 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (1250 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
CDC42Uncharacterized protein. (191 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1193 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3088 aa)
ABLIM1Actin binding LIM protein 1. (776 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
AGAP3ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (907 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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