STRINGSTRING
COL2A1 COL2A1 COL6A3 COL6A3 SPTBN2 SPTBN2 ARTN ARTN SPTBN1 SPTBN1 MAPK1 MAPK1 SPTAN1 SPTAN1 CACNB3 CACNB3 PTPRA PTPRA COL5A3 COL5A3 PSPN PSPN PTK2 PTK2 COL5A2 COL5A2 GFRA2 GFRA2 CACNA1H CACNA1H CACNB4 CACNB4 ENSPCOP00000023926 ENSPCOP00000023926 GFRA1 GFRA1 CNTN2 CNTN2 COL6A6 COL6A6 GDNF GDNF NCAM1 NCAM1 COL9A2 COL9A2 COL5A1 COL5A1 COL4A5 COL4A5 CACNA1S CACNA1S ST8SIA2 ST8SIA2 PTPRE PTPRE HRAS HRAS COL4A1 COL4A1 CREB1 CREB1 SRC SRC CACNB2 CACNB2 GRB2 GRB2 COL4A2 COL4A2 CACNA1G CACNA1G COL9A1 COL9A1 CACNA1C CACNA1C CACNA1I CACNA1I CACNA1D CACNA1D SPTA1 SPTA1 CSDE1 CSDE1 CACNB1 CACNB1 NRTN NRTN GFRA4 GFRA4 COL6A2 COL6A2 KRAS KRAS COL4A3 COL4A3 SOS1 SOS1 FYN FYN MAPK3 MAPK3 COL6A1 COL6A1 AGRN AGRN ST8SIA4 ST8SIA4 NRAS NRAS RPS6KA5 RPS6KA5 SPTB SPTB SPTBN4 SPTBN4 ENSPCOP00000002686 ENSPCOP00000002686 COL4A4 COL4A4 FGFR1 FGFR1 COL3A1 COL3A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL2A1Collagen type II alpha 1 chain. (1487 aa)
COL6A3Collagen type VI alpha 3 chain. (3101 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
ARTNArtemin. (229 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
COL5A3Collagen type V alpha 3 chain. (1688 aa)
PSPNPersephin. (154 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
COL5A2Collagen type V alpha 2 chain. (1209 aa)
GFRA2GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (464 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2221 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (520 aa)
ENSPCOP00000023926Uncharacterized protein. (364 aa)
GFRA1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (468 aa)
CNTN2Contactin 2. (1040 aa)
COL6A6Collagen type VI alpha 6 chain. (2266 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
NCAM1Neural cell adhesion molecule 1. (866 aa)
COL9A2Collagen type IX alpha 2 chain. (688 aa)
COL5A1Collagen type V alpha 1 chain. (1843 aa)
COL4A5Collagen type IV alpha 5 chain. (1516 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1544 aa)
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (375 aa)
PTPREReceptor-type tyrosine-protein phosphatase. (701 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
COL4A1Collagen type IV alpha 1 chain. (1670 aa)
CREB1cAMP responsive element binding protein 1. (280 aa)
SRCTyrosine-protein kinase. (543 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (660 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
COL4A2Collagen type IV alpha 2 chain. (1711 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2381 aa)
COL9A1Collagen type IX alpha 1 chain. (801 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2016 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1991 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2180 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2421 aa)
CSDE1Cold shock domain containing E1. (798 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (676 aa)
NRTNNeurturin. (197 aa)
GFRA4GDNF family receptor alpha 4. (259 aa)
COL6A2Collagen type VI alpha 2 chain. (1012 aa)
KRASUncharacterized protein. (75 aa)
COL4A3Collagen type IV alpha 3 chain. (1545 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
FYNTyrosine-protein kinase. (537 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
COL6A1Collagen type VI alpha 1 chain. (1031 aa)
AGRNAgrin. (2040 aa)
ST8SIA4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (359 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
RPS6KA5Ribosomal protein S6 kinase A5. (643 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2330 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2533 aa)
ENSPCOP00000002686CSD_1 domain-containing protein. (293 aa)
COL4A4Collagen type IV alpha 4 chain. (1691 aa)
FGFR1Fibroblast growth factor receptor. (846 aa)
COL3A1Collagen type III alpha 1 chain. (1371 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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