STRINGSTRING
RBBP5 RBBP5 ENSPCOP00000023542 ENSPCOP00000023542 APC2 APC2 TLE4 TLE4 CTNNB1 CTNNB1 TLE3 TLE3 TCF7L2 TCF7L2 BHMG1 BHMG1 XIAP XIAP SOX17 SOX17 SOX15 SOX15 CHD8 CHD8 SOX30 SOX30 SOX1 SOX1 SOX12 SOX12 ENSPCOP00000004787 ENSPCOP00000004787 CTBP1 CTBP1 LEF1 LEF1 UBA52 UBA52 ENSPCOP00000012718 ENSPCOP00000012718 ENSPCOP00000014538 ENSPCOP00000014538 SOX5 SOX5 CTNNBIP1 CTNNBIP1 RPS27A RPS27A ENSPCOP00000016328 ENSPCOP00000016328 BTRC BTRC SOX13 SOX13 MEN1 MEN1 ENSPCOP00000018904 ENSPCOP00000018904 AKT2 AKT2 KMT2D KMT2D XPO1 XPO1 SOX8 SOX8 SOX4 SOX4 SOX2 SOX2 ZBTB44 ZBTB44 TCF7 TCF7 TLE2 TLE2 YWHAZ YWHAZ TLE1 TLE1 LOC105820322 LOC105820322 TLE7 TLE7 SOX6 SOX6 TLE6 TLE6 SOX11 SOX11 TCF7L1 TCF7L1 SOX9 SOX9 AKT1 AKT1 APC APC ENSPCOP00000028788 ENSPCOP00000028788 SOX14 SOX14 LOC105816759 LOC105816759 SOX21 SOX21 HMGXB4 HMGXB4 HDAC1 HDAC1 ASH2L ASH2L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (552 aa)
ENSPCOP00000023542Ubiquitin-like domain-containing protein. (112 aa)
APC2APC regulator of WNT signaling pathway 2. (2300 aa)
TLE4TLE family member 4, transcriptional corepressor. (796 aa)
CTNNB1Catenin beta 1. (781 aa)
TLE3TLE family member 3, transcriptional corepressor. (784 aa)
TCF7L2Transcription factor 7 like 2. (619 aa)
BHMG1Basic helix-loop-helix and HMG-box containing 1. (611 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
SOX17SRY-box transcription factor 17. (413 aa)
SOX15SRY-box transcription factor 15. (233 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2592 aa)
SOX30SRY-box transcription factor 30. (757 aa)
SOX1SRY-box transcription factor 1. (390 aa)
SOX12Transcription factor SOX. (314 aa)
ENSPCOP00000004787Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (445 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
LEF1Lymphoid enhancer binding factor 1. (432 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
ENSPCOP00000012718Ubiquitin-like domain-containing protein. (74 aa)
ENSPCOP0000001453814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)
SOX5SRY-box transcription factor 5. (763 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
RPS27ARibosomal protein S27a. (156 aa)
ENSPCOP00000016328Uncharacterized protein. (111 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (609 aa)
SOX13SRY-box transcription factor 13. (615 aa)
MEN1Menin 1. (616 aa)
ENSPCOP00000018904Ubiquitin-like domain-containing protein. (131 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
KMT2DLysine methyltransferase 2D. (5467 aa)
XPO1Exportin 1. (1080 aa)
SOX8SRY-box transcription factor 8. (462 aa)
SOX4Transcription factor SOX. (479 aa)
SOX2SRY-box transcription factor 2. (321 aa)
ZBTB44Zinc finger and BTB domain containing 44. (616 aa)
TCF7Transcription factor 7. (303 aa)
TLE2TLE family member 2, transcriptional corepressor. (737 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (256 aa)
TLE1TLE family member 1, transcriptional corepressor. (774 aa)
LOC105820322Ubiquitin-like domain-containing protein. (77 aa)
TLE7TLE family member 7. (443 aa)
SOX6SRY-box transcription factor 6. (828 aa)
TLE6TLE family member 6, subcortical maternal complex member. (567 aa)
SOX11Transcription factor SOX. (442 aa)
TCF7L1Transcription factor 7 like 1. (590 aa)
SOX9SRY-box transcription factor 9. (505 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
ENSPCOP00000028788Uncharacterized protein. (171 aa)
SOX14SRY-box transcription factor 14. (240 aa)
LOC105816759Ubiquitin-like domain-containing protein. (156 aa)
SOX21SRY-box transcription factor 21. (276 aa)
HMGXB4HMG-box containing 4. (601 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (639 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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