STRINGSTRING
TNFRSF14 TNFRSF14 PPP4R1 PPP4R1 MLST8 MLST8 PPP2R5C PPP2R5C TRIB3 TRIB3 PPP4R4 PPP4R4 ENSPCOP00000000722 ENSPCOP00000000722 PPP2R5E PPP2R5E MTOR MTOR ENSPCOP00000002561 ENSPCOP00000002561 ENSPCOP00000002927 ENSPCOP00000002927 CD80 CD80 PPP2R1A PPP2R1A PDPK1 PDPK1 CD3D CD3D HLA-DQB1 HLA-DQB1 PPP2CB PPP2CB LOC105810148 LOC105810148 PAK1 PAK1 HLA-DPA1 HLA-DPA1 PIK3R3 PIK3R3 CD274 CD274 FYN FYN CD4 CD4 FNBP4 FNBP4 RELCH RELCH LCK LCK FNDC3A FNDC3A CD3E CD3E CD28 CD28 PTPN6 PTPN6 ENSPCOP00000013862 ENSPCOP00000013862 VAV1 VAV1 PIK3CA PIK3CA ENSPCOP00000031440 ENSPCOP00000031440 RICTOR RICTOR CSK CSK ENSPCOP00000030367 ENSPCOP00000030367 CTLA4 CTLA4 GRAP2 GRAP2 THEM4 THEM4 PTPN11 PTPN11 AKT1 AKT1 PPP2R5B PPP2R5B AKT3 AKT3 HLA-DRA HLA-DRA LOC105820073 LOC105820073 BTLA BTLA PPP2CA PPP2CA ICOS ICOS LYN LYN PDCD1LG2 PDCD1LG2 MAP3K14 MAP3K14 PPP2R5A PPP2R5A CD276 CD276 PAK3 PAK3 CDC42 CDC42 MAPKAP1 MAPKAP1 PDCD1 PDCD1 LOC105817835 LOC105817835 PAK2 PAK2 PPP2R1B PPP2R1B ICOSLG ICOSLG FNDC3B FNDC3B CD86 CD86 AKT2 AKT2 SRC SRC PIK3R1 PIK3R1 PPP2R5D PPP2R5D PIK3R2 PIK3R2 GRB2 GRB2 ENSPCOP00000017161 ENSPCOP00000017161 CD3G CD3G CD247 CD247
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFRSF14TNF receptor superfamily member 14. (267 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (906 aa)
MLST8MTOR associated protein, LST8 homolog. (326 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (542 aa)
TRIB3Tribbles pseudokinase 3. (367 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (826 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2536 aa)
ENSPCOP00000002561Uncharacterized protein. (546 aa)
ENSPCOP00000002927Uncharacterized protein. (160 aa)
CD80CD80 molecule. (265 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (558 aa)
CD3DUncharacterized protein. (97 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (261 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
LOC105810148Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
PIK3R3Uncharacterized protein. (454 aa)
CD274CD274 molecule. (244 aa)
FYNTyrosine-protein kinase. (537 aa)
CD4CD4 molecule. (452 aa)
FNBP4Formin binding protein 4. (870 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1217 aa)
LCKTyrosine-protein kinase. (417 aa)
FNDC3AFibronectin type III domain containing 3A. (1044 aa)
CD3ECD3e molecule. (187 aa)
CD28CD28 molecule. (220 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
ENSPCOP00000013862SER_THR_PHOSPHATASE domain-containing protein. (209 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
ENSPCOP00000031440annotation not available (119 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1646 aa)
CSKTyrosine-protein kinase. (450 aa)
ENSPCOP00000030367Ig-like domain-containing protein. (214 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
GRAP2GRB2 related adaptor protein 2. (326 aa)
THEM4Thioesterase superfamily member 4. (202 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (501 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
LOC105820073WRNPLPNID domain-containing protein. (958 aa)
BTLAB and T lymphocyte associated. (293 aa)
PPP2CASerine/threonine-protein phosphatase. (295 aa)
ICOSInducible T cell costimulator. (200 aa)
LYNTyrosine-protein kinase. (512 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (274 aa)
MAP3K14Uncharacterized protein. (151 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa)
CD276CD276 molecule. (332 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
CDC42Uncharacterized protein. (191 aa)
MAPKAP1MAPK associated protein 1. (492 aa)
PDCD1Programmed cell death 1. (287 aa)
LOC105817835MHC_II_beta domain-containing protein. (175 aa)
PAK2Non-specific serine/threonine protein kinase. (492 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (552 aa)
ICOSLGUncharacterized protein. (299 aa)
FNDC3BFibronectin type III domain containing 3B. (1156 aa)
CD86CD86 molecule. (336 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SRCTyrosine-protein kinase. (543 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (598 aa)
PIK3R2Uncharacterized protein. (726 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSPCOP00000017161Mitogen-activated protein kinase kinase kinase 8. (119 aa)
CD3GCD3g molecule. (182 aa)
CD247CD247 molecule. (164 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (38%) [HD]