STRINGSTRING
PTGIR PTGIR ATP2B4 ATP2B4 ENSPCOP00000013862 ENSPCOP00000013862 PTPN6 PTPN6 ORAI3 ORAI3 ATP2A3 ATP2A3 LOC105811387 LOC105811387 GNG3 GNG3 SLC8A1 SLC8A1 TRPC7 TRPC7 ENSPCOP00000010360 ENSPCOP00000010360 GUCY1A2 GUCY1A2 NOS3 NOS3 LOC105819868 LOC105819868 GUCY1B1 GUCY1B1 PLA2G4A PLA2G4A ENSPCOP00000008641 ENSPCOP00000008641 GUCY1A1 GUCY1A1 P2RX2 P2RX2 PPP2CB PPP2CB GNG8 GNG8 MILR1 MILR1 GNB2 GNB2 GNG10 GNG10 GNGT2 GNGT2 ITPR2 ITPR2 PDE9A PDE9A PPP2R1A PPP2R1A ATP2A1 ATP2A1 P2RX5 P2RX5 P2RX4 P2RX4 PECAM1 PECAM1 ENSPCOP00000002676 ENSPCOP00000002676 ENSPCOP00000002561 ENSPCOP00000002561 PDE1A PDE1A ATP2B1 ATP2B1 SRI SRI GNG4 GNG4 PRKG1 PRKG1 PPP2R5E PPP2R5E P2RX6 P2RX6 GNG12 GNG12 ORAI2 ORAI2 PDE10A PDE10A PPP2R5C PPP2R5C MAPK14 MAPK14 FGR FGR PPP2R5D PPP2R5D REEP4 REEP4 LOC105823863 LOC105823863 KCNMB4 KCNMB4 P2RX1 P2RX1 ATP2A2 ATP2A2 GNB5 GNB5 SLC8A3 SLC8A3 PDE1B PDE1B ITPR3 ITPR3 KCNMB1 KCNMB1 GNB1 GNB1 KCNMB2 KCNMB2 GNB4 GNB4 ORAI1 ORAI1 TRPC6 TRPC6 PPP2R5A PPP2R5A SLC8A2 SLC8A2 GNG13 GNG13 ENSPCOP00000023702 ENSPCOP00000023702 GNG2 GNG2 NOS2 NOS2 MRVI1 MRVI1 KCNMA1 KCNMA1 LRP8 LRP8 ITPR1 ITPR1 PPP2CA PPP2CA ENSPCOP00000026249 ENSPCOP00000026249 PDE2A PDE2A P2RX3 P2RX3 PDE11A PDE11A PDE5A PDE5A LOC105813679 LOC105813679 PPP2R5B PPP2R5B PTPN11 PTPN11 ENSPCOP00000029571 ENSPCOP00000029571 P2RX7 P2RX7 GNG7 GNG7 GNAS GNAS STIM1 STIM1 GNB3 GNB3 APOB APOB NOS1 NOS1 REEP3 REEP3 ATP2B3 ATP2B3 TRPC3 TRPC3 PPP2R1B PPP2R1B REEP2 REEP2 GNG11 GNG11 PAFAH2 PAFAH2 ATP2B2 ATP2B2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGIRProstaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (386 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1204 aa)
ENSPCOP00000013862SER_THR_PHOSPHATASE domain-containing protein. (209 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
ORAI3ORAI calcium release-activated calcium modulator 3. (297 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1033 aa)
LOC105811387XRCC1_N domain-containing protein. (142 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (974 aa)
TRPC7Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (862 aa)
ENSPCOP00000010360AGC-kinase C-terminal domain-containing protein. (86 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (729 aa)
NOS3Nitric oxide synthase 3. (994 aa)
LOC105819868Protein kinase domain-containing protein. (302 aa)
GUCY1B1Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (176 aa)
PLA2G4APhospholipase A2. (749 aa)
ENSPCOP00000008641Uncharacterized protein. (715 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (473 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
MILR1Mast cell immunoglobulin like receptor 1. (339 aa)
GNB2G protein subunit beta 2. (340 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2702 aa)
PDE9APhosphodiesterase. (598 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1028 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (404 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (698 aa)
ENSPCOP00000002676Uncharacterized protein; Belongs to the transient receptor (TC 1.A.4) family. (879 aa)
ENSPCOP00000002561Uncharacterized protein. (546 aa)
PDE1APhosphodiesterase 1A; Belongs to the cyclic nucleotide phosphodiesterase family. (424 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1258 aa)
SRISorcin. (198 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKG1Protein kinase cGMP-dependent 1. (593 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (440 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ORAI2ORAI calcium release-activated calcium modulator 2. (257 aa)
PDE10APhosphodiesterase. (679 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (542 aa)
MAPK14Mitogen-activated protein kinase 14. (340 aa)
FGRTyrosine-protein kinase. (495 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (598 aa)
REEP4Receptor expression-enhancing protein. (257 aa)
LOC105823863Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNMB4Potassium calcium-activated channel subfamily M regulatory beta subunit 4. (210 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
GNB5G protein subunit beta 5. (395 aa)
SLC8A3Solute carrier family 8 member A3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (927 aa)
PDE1BPhosphodiesterase. (535 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2664 aa)
KCNMB1Potassium calcium-activated channel subfamily M regulatory beta subunit 1. (191 aa)
GNB1G protein subunit beta 1. (334 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
GNB4G protein subunit beta 4. (321 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (307 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (931 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa)
SLC8A2Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
GNG13G protein subunit gamma 13. (67 aa)
ENSPCOP00000023702Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (61 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (109 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1104 aa)
MRVI1Murine retrovirus integration site 1 homolog. (911 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1286 aa)
LRP8LDL receptor related protein 8. (956 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2732 aa)
PPP2CASerine/threonine-protein phosphatase. (295 aa)
ENSPCOP00000026249Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (79 aa)
PDE2APhosphodiesterase. (940 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
PDE11APhosphodiesterase. (933 aa)
PDE5APhosphodiesterase. (839 aa)
LOC105813679Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (744 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (501 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
ENSPCOP00000029571HNOB domain-containing protein. (173 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNASUncharacterized protein. (394 aa)
STIM1Stromal interaction molecule 1. (784 aa)
GNB3G protein subunit beta 3. (340 aa)
APOBApolipoprotein B. (4538 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1434 aa)
REEP3Receptor expression-enhancing protein. (255 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (552 aa)
REEP2Receptor expression-enhancing protein. (255 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (392 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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