STRINGSTRING
CRKL CRKL ENSPCOP00000000722 ENSPCOP00000000722 RAPGEF1 RAPGEF1 LOC105820322 LOC105820322 IL5RA IL5RA JAK3 JAK3 UBA52 UBA52 CSF2RA CSF2RA IL5 IL5 TEC TEC PIK3R3 PIK3R3 IL2RA IL2RA FYN FYN SOS1 SOS1 SYK SYK CSF2 CSF2 INPPL1 INPPL1 CBL CBL HCK HCK ENSPCOP00000012718 ENSPCOP00000012718 JAK1 JAK1 INPP5D INPP5D IL2RB IL2RB PTPN6 PTPN6 GAB1 GAB1 ENSPCOP00000014538 ENSPCOP00000014538 VAV1 VAV1 PIK3CA PIK3CA RPS27A RPS27A PIK3CB PIK3CB GRB2 GRB2 CRK CRK PIK3R2 PIK3R2 PIK3R1 PIK3R1 ENSPCOP00000018904 ENSPCOP00000018904 IL2RG IL2RG GAB2 GAB2 STAT5A STAT5A ENSPCOP00000023542 ENSPCOP00000023542 IL3RA IL3RA LYN LYN STAT5B STAT5B LOC105816759 LOC105816759 PTPN11 PTPN11 CSF2RB CSF2RB PIK3CD PIK3CD YWHAZ YWHAZ IL2 IL2 SHC1 SHC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
ENSPCOP00000000722Protein kinase domain-containing protein. (67 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1103 aa)
LOC105820322Ubiquitin-like domain-containing protein. (77 aa)
IL5RAInterleukin 5 receptor subunit alpha. (333 aa)
JAK3Tyrosine-protein kinase. (1123 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
CSF2RAFibronectin type-III domain-containing protein. (388 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (133 aa)
TECTyrosine-protein kinase. (625 aa)
PIK3R3Uncharacterized protein. (454 aa)
IL2RAInterleukin 2 receptor subunit alpha. (271 aa)
FYNTyrosine-protein kinase. (537 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
SYKSpleen associated tyrosine kinase. (637 aa)
CSF2Colony stimulating factor 2. (146 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
CBLCbl proto-oncogene. (891 aa)
HCKTyrosine-protein kinase. (524 aa)
ENSPCOP00000012718Ubiquitin-like domain-containing protein. (74 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1178 aa)
IL2RBInterleukin 2 receptor subunit beta. (558 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
GAB1GRB2 associated binding protein 1. (683 aa)
ENSPCOP0000001453814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)
VAV1Vav guanine nucleotide exchange factor 1. (806 aa)
PIK3CAPhosphatidylinositol 3-kinase catalytic subunit type 3. (933 aa)
RPS27ARibosomal protein S27a. (156 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
PIK3R2Uncharacterized protein. (726 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSPCOP00000018904Ubiquitin-like domain-containing protein. (131 aa)
IL2RGFibronectin type-III domain-containing protein. (386 aa)
GAB2GRB2 associated binding protein 2. (679 aa)
STAT5ASignal transducer and activator of transcription. (805 aa)
ENSPCOP00000023542Ubiquitin-like domain-containing protein. (112 aa)
IL3RAInterleukin 3 receptor subunit alpha. (377 aa)
LYNTyrosine-protein kinase. (512 aa)
STAT5BSignal transducer and activator of transcription. (667 aa)
LOC105816759Ubiquitin-like domain-containing protein. (156 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (906 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (256 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (153 aa)
SHC1SHC adaptor protein 1. (582 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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