STRINGSTRING
ENSPCOP00000028080 ENSPCOP00000028080 ENSPCOP00000000292 ENSPCOP00000000292 APIP APIP STUB1 STUB1 BCAP29 BCAP29 ACIN1 ACIN1 PSMD2 PSMD2 LOC105810841 LOC105810841 LMNTD1 LMNTD1 FAS FAS KPNA1 KPNA1 LOC105821288 LOC105821288 SFN SFN LOC105810867 LOC105810867 SH3GLB1 SH3GLB1 H1-5 H1-5 SH3GLB2 SH3GLB2 CHMP7 CHMP7 ENSPCOP00000002718 ENSPCOP00000002718 PMAIP1 PMAIP1 C1QBP C1QBP BIRC3 BIRC3 OCLN OCLN PSMC2 PSMC2 ITCH ITCH LOC105820322 LOC105820322 ENSPCOP00000003641 ENSPCOP00000003641 ENSPCOP00000003656 ENSPCOP00000003656 BNIP5 BNIP5 CFLAR CFLAR SEPTIN5 SEPTIN5 CARD18 CARD18 IGDCC3 IGDCC3 PSMA7 PSMA7 UBA52 UBA52 PSMD1 PSMD1 BOK BOK ENSPCOP00000004684 ENSPCOP00000004684 H1-4 H1-4 HMGB1 HMGB1 FLOT1 FLOT1 ENSPCOP00000005540 ENSPCOP00000005540 PPP1R13B PPP1R13B DFFB DFFB PSMA4 PSMA4 ENSPCOP00000005855 ENSPCOP00000005855 YWHAG YWHAG PSMD12 PSMD12 UNC5B UNC5B PSMB6 PSMB6 ENSPCOP00000007435 ENSPCOP00000007435 DYNLL1 DYNLL1 DAPK2 DAPK2 ROCK1 ROCK1 TMEM198 TMEM198 ADD1 ADD1 DSP DSP ENSPCOP00000008176 ENSPCOP00000008176 PSME4 PSME4 BCL2L10 BCL2L10 MAPK3 MAPK3 CDH1 CDH1 BIRC7 BIRC7 HMGB2 HMGB2 STK26 STK26 LMNB1 LMNB1 PKP1 PKP1 ENSPCOP00000008906 ENSPCOP00000008906 DAPK1 DAPK1 DSG3 DSG3 CDC37 CDC37 IRF2 IRF2 SCIN SCIN IRF1 IRF1 APPL1 APPL1 XIAP XIAP ENSPCOP00000009886 ENSPCOP00000009886 PSMA8 PSMA8 APPL2 APPL2 PELI1 PELI1 IL1B IL1B CAPG CAPG CASP6 CASP6 LY96 LY96 LMNTD2 LMNTD2 PSMA1 PSMA1 OGT OGT DSG1 DSG1 CHMP2A CHMP2A TJP1 TJP1 UACA UACA PSMB9 PSMB9 PSMB1 PSMB1 PSMD6 PSMD6 ENSPCOP00000012718 ENSPCOP00000012718 BCAP31 BCAP31 CLSPN CLSPN BMF BMF PSME1 PSME1 PPP3CC PPP3CC GAS2 GAS2 TP73 TP73 SEPTIN4 SEPTIN4 IL1A IL1A LOC105810279 LOC105810279 CHMP6 CHMP6 PSME3 PSME3 ENSPCOP00000013591 ENSPCOP00000013591 ENSPCOP00000013697 ENSPCOP00000013697 GSDME GSDME PSMA6 PSMA6 PSMA3 PSMA3 ENSPCOP00000014399 ENSPCOP00000014399 LOC105813278 LOC105813278 ENSPCOP00000014538 ENSPCOP00000014538 MAGED1 MAGED1 CASP1 CASP1 TRAF2 TRAF2 CHMP4B CHMP4B LOC105813790 LOC105813790 OPA1 OPA1 PSMF1 PSMF1 DYNLL2 DYNLL2 PDCD6IP PDCD6IP LOC105824240 LOC105824240 PSMD9 PSMD9 AVEN AVEN VIM VIM RPS27A RPS27A GSN GSN PRKN PRKN PSMD10 PSMD10 PSMD14 PSMD14 TRADD TRADD MLKL MLKL TJP3 TJP3 MAPT MAPT BAK1 BAK1 APAF1 APAF1 MAP2 MAP2 CASP3 CASP3 TFDP1 TFDP1 LOC105812452 LOC105812452 PSMC3 PSMC3 CASP7 CASP7 E2F1 E2F1 PSMD11 PSMD11 LOC105822166 LOC105822166 ENSPCOP00000018566 ENSPCOP00000018566 ENSPCOP00000018904 ENSPCOP00000018904 AKT2 AKT2 GSDMB GSDMB LOC105814628 LOC105814628 BAX BAX CHMP4C CHMP4C PSMD3 PSMD3 PSMD8 PSMD8 PSMB5 PSMB5 TJP2 TJP2 MDP1 MDP1 LOC105808023 LOC105808023 PPP3R1 PPP3R1 BCL2L1 BCL2L1 LOC105815346 LOC105815346 BCL2 BCL2 DNM1L DNM1L PAK2 PAK2 BIRC2 BIRC2 LOC105826870 LOC105826870 CD14 CD14 FADD FADD PSMB10 PSMB10 PSMB3 PSMB3 MAPK10 MAPK10 STK24 STK24 STK25 STK25 NPVF NPVF DAPK3 DAPK3 PLEC PLEC PSMC1 PSMC1 DSG2 DSG2 CTNNB1 CTNNB1 TFDP2 TFDP2 APC2 APC2 FLOT2 FLOT2 ENSPCOP00000023228 ENSPCOP00000023228 PSMB4 PSMB4 YWHAE YWHAE ENSPCOP00000023440 ENSPCOP00000023440 ENSPCOP00000023542 ENSPCOP00000023542 HMGB3 HMGB3 IGDCC4 IGDCC4 CASP8 CASP8 FNTA FNTA PSMC5 PSMC5 TNFSF10 TNFSF10 RIPK1 RIPK1 ENSPCOP00000024369 ENSPCOP00000024369 ENSPCOP00000024480 ENSPCOP00000024480 BCL2L11 BCL2L11 H1-8 H1-8 UNC5A UNC5A SEPTIN4-2 SEPTIN4-2 PSMA5 PSMA5 PSMD13 PSMD13 OMA1 OMA1 ENSPCOP00000025404 ENSPCOP00000025404 PSMB2 PSMB2 PSMC4 PSMC4 PTK2 PTK2 DIABLO DIABLO FASLG FASLG ELANE ELANE DFFA DFFA TICAM1 TICAM1 YWHAH YWHAH PRKCD PRKCD HP1BP3 HP1BP3 PSMD5 PSMD5 PSMA2 PSMA2 DBNL DBNL ENSPCOP00000027105 ENSPCOP00000027105 BMX BMX PRKCQ PRKCQ LOC105816759 LOC105816759 SDCBP SDCBP KPNB1 KPNB1 LOC105807375 LOC105807375 GZMB GZMB TLR4 TLR4 MAPK8 MAPK8 LOC105823889 LOC105823889 AKT3 AKT3 LOC105812072 LOC105812072 APC APC AKT1 AKT1 ARHGAP10 ARHGAP10 YWHAQ YWHAQ CHMP2B CHMP2B PSMD4 PSMD4 PSMB7 PSMB7 ENSPCOP00000029247 ENSPCOP00000029247 SPTAN1 SPTAN1 CASP9 CASP9 PSMD7 PSMD7 MAPK1 MAPK1 STAT3 STAT3 ENSPCOP00000030477 ENSPCOP00000030477 ENSPCOP00000030534 ENSPCOP00000030534 YWHAZ YWHAZ YWHAB YWHAB GSDMD GSDMD PSMB8 PSMB8 BAD BAD SEPTIN1 SEPTIN1 NMT1 NMT1 HSP90AA1 HSP90AA1 TP63 TP63 LMNA LMNA LMNB2 LMNB2 RIPK3 RIPK3 LOC105822171 LOC105822171 ENSPCOP00000031317 ENSPCOP00000031317 PSME2 PSME2 TP53 TP53 ENSPCOP00000031861 ENSPCOP00000031861 LOC105815609 LOC105815609 BID BID
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCOP00000028080Uncharacterized protein. (597 aa)
ENSPCOP00000000292Uncharacterized protein. (404 aa)
APIPMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (242 aa)
STUB1STIP1 homology and U-box containing protein 1. (304 aa)
BCAP29B cell receptor associated protein 29. (241 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1339 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
LOC105810841Proteasome subunit alpha type. (263 aa)
LMNTD1Lamin tail domain containing 1. (355 aa)
FASFas cell surface death receptor. (309 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
LOC105821288TPR_REGION domain-containing protein. (438 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
LOC105810867Proteasome subunit alpha type. (263 aa)
SH3GLB1SH3 domain containing GRB2 like, endophilin B1. (403 aa)
H1-5Histone cluster 1 H1 family member b. (226 aa)
SH3GLB2SH3 domain containing GRB2 like, endophilin B2. (404 aa)
CHMP7Charged multivesicular body protein 7. (450 aa)
ENSPCOP00000002718Uncharacterized protein. (210 aa)
PMAIP1Uncharacterized protein. (54 aa)
C1QBPUncharacterized protein. (281 aa)
BIRC3Baculoviral IAP repeat containing 3. (597 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (516 aa)
PSMC2AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
ITCHE3 ubiquitin-protein ligase. (860 aa)
LOC105820322Ubiquitin-like domain-containing protein. (77 aa)
ENSPCOP00000003641Uncharacterized protein. (213 aa)
ENSPCOP00000003656Uncharacterized protein. (213 aa)
BNIP5BCL2 interacting protein 5. (653 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (333 aa)
SEPTIN5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
CARD18Caspase recruitment domain family member 18. (91 aa)
IGDCC3Immunoglobulin superfamily DCC subclass member 3. (778 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (933 aa)
BOKBCL2 family apoptosis regulator BOK. (213 aa)
ENSPCOP00000004684Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
H1-4Histone cluster 1 H1 family member e. (219 aa)
HMGB1Uncharacterized protein. (187 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ENSPCOP00000005540Uncharacterized protein; Belongs to the peptidase C14A family. (199 aa)
PPP1R13BProtein phosphatase 1 regulatory subunit 13B. (1088 aa)
DFFBDNA fragmentation factor subunit beta. (338 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
ENSPCOP00000005855Uncharacterized protein. (259 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
PSMD12PCI domain-containing protein. (480 aa)
UNC5BUnc-5 netrin receptor B. (932 aa)
PSMB6Proteasome subunit beta. (241 aa)
ENSPCOP00000007435DUF4203 domain-containing protein. (348 aa)
DYNLL1Dynein light chain. (89 aa)
DAPK2Death associated protein kinase 2; Belongs to the protein kinase superfamily. (488 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1316 aa)
TMEM198Transmembrane protein 198. (360 aa)
ADD1Adducin 1. (751 aa)
DSPDesmoplakin. (2868 aa)
ENSPCOP00000008176Proteasome subunit alpha type. (200 aa)
PSME4Proteasome activator subunit 4. (1638 aa)
BCL2L10Uncharacterized protein. (192 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (904 aa)
BIRC7Baculoviral IAP repeat containing 7. (283 aa)
HMGB2Uncharacterized protein. (210 aa)
STK26Serine/threonine kinase 26. (372 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (583 aa)
PKP1Plakophilin 1. (746 aa)
ENSPCOP00000008906PCI domain-containing protein. (387 aa)
DAPK1Death associated protein kinase 1. (1430 aa)
DSG3Desmoglein 3; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1001 aa)
CDC37Cell division cycle 37. (376 aa)
IRF2Interferon regulatory factor 2. (350 aa)
SCINScinderin. (589 aa)
IRF1Interferon regulatory factor. (324 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (661 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ENSPCOP00000009886AAA domain-containing protein. (188 aa)
PSMA8Proteasome subunit alpha type. (208 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (591 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
CAPGCapping actin protein, gelsolin like. (348 aa)
CASP6Caspase 6; Belongs to the peptidase C14A family. (293 aa)
LY96Lymphocyte antigen 96. (160 aa)
LMNTD2Lamin tail domain containing 2. (632 aa)
PSMA1Proteasome endopeptidase complex. (217 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1043 aa)
CHMP2ACharged multivesicular body protein 2A. (231 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1768 aa)
UACAUveal autoantigen with coiled-coil domains and ankyrin repeats. (1341 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB1Proteasome subunit beta 1. (232 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (440 aa)
ENSPCOP00000012718Ubiquitin-like domain-containing protein. (74 aa)
BCAP31B cell receptor associated protein 31. (297 aa)
CLSPNClaspin. (1329 aa)
BMFBcl2 modifying factor. (184 aa)
PSME1Proteasome activator subunit 1. (249 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
GAS2Growth arrest specific 2. (314 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (588 aa)
SEPTIN4Septin 4. (560 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (270 aa)
LOC105810279Uncharacterized protein. (221 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
PSME3Proteasome activator subunit 3. (184 aa)
ENSPCOP00000013591Proteasome endopeptidase complex. (228 aa)
ENSPCOP00000013697BAR domain-containing protein. (147 aa)
GSDMEGasdermin E. (492 aa)
PSMA6Proteasome subunit alpha type. (145 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
ENSPCOP00000014399Proteasome subunit beta. (212 aa)
LOC105813278Uncharacterized protein. (203 aa)
ENSPCOP0000001453814_3_3 domain-containing protein; Belongs to the 14-3-3 family. (256 aa)
MAGED1MAGE family member D1. (839 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (254 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
LOC105813790Uncharacterized protein. (205 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (997 aa)
PSMF1Proteasome inhibitor subunit 1. (220 aa)
DYNLL2Dynein light chain. (89 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
LOC105824240Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (248 aa)
PSMD9PDZ domain-containing protein. (223 aa)
AVENApoptosis and caspase activation inhibitor. (284 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
RPS27ARibosomal protein S27a. (156 aa)
GSNGelsolin. (778 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (460 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (274 aa)
TRADDTNFRSF1A associated via death domain. (309 aa)
MLKLMixed lineage kinase domain like pseudokinase. (419 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (922 aa)
MAPTMicrotubule-associated protein. (775 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
APAF1Apoptotic peptidase activating factor 1. (1204 aa)
MAP2Microtubule-associated protein. (1794 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
TFDP1Transcription factor. (409 aa)
LOC105812452HATPase_c domain-containing protein. (680 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (341 aa)
E2F1E2F transcription factor 1. (436 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
LOC105822166Uncharacterized protein; Belongs to the peptidase C14A family. (285 aa)
ENSPCOP00000018566Uncharacterized protein. (113 aa)
ENSPCOP00000018904Ubiquitin-like domain-containing protein. (131 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
GSDMBGasdermin B. (398 aa)
LOC105814628HMG box domain-containing protein. (187 aa)
BAXBCL2 associated X, apoptosis regulator. (199 aa)
CHMP4CCharged multivesicular body protein 4C. (135 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (351 aa)
PSMB5Proteasome subunit beta. (263 aa)
TJP2Uncharacterized protein; Belongs to the MAGUK family. (1242 aa)
MDP1Magnesium dependent phosphatase 1. (164 aa)
LOC105808023Uncharacterized protein. (99 aa)
PPP3R1Uncharacterized protein. (189 aa)
BCL2L1BCL2 like 1. (233 aa)
LOC105815346Pr_beta_C domain-containing protein. (270 aa)
BCL2BCL2 apoptosis regulator. (234 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
PAK2Non-specific serine/threonine protein kinase. (492 aa)
BIRC2Baculoviral IAP repeat containing 2. (619 aa)
LOC105826870Uncharacterized protein. (244 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (205 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB3Proteasome subunit beta. (205 aa)
MAPK10Mitogen-activated protein kinase. (473 aa)
STK24Serine/threonine kinase 24. (443 aa)
STK25Serine/threonine kinase 25. (426 aa)
NPVFNeuropeptide VF precursor. (198 aa)
DAPK3Death associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
PLECPlectin. (4689 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (396 aa)
DSG2Desmoglein 2. (1029 aa)
CTNNB1Catenin beta 1. (781 aa)
TFDP2Transcription factor. (405 aa)
APC2APC regulator of WNT signaling pathway 2. (2300 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ENSPCOP00000023228Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (99 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa)
ENSPCOP00000023440Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (95 aa)
ENSPCOP00000023542Ubiquitin-like domain-containing protein. (112 aa)
HMGB3Uncharacterized protein. (201 aa)
IGDCC4Immunoglobulin superfamily DCC subclass member 4. (1250 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (395 aa)
FNTAFarnesyltransferase, CAAX box, alpha. (309 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (288 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (643 aa)
ENSPCOP00000024369Uncharacterized protein; Belongs to the intermediate filament family. (156 aa)
ENSPCOP00000024480Uncharacterized protein. (103 aa)
BCL2L11BCL2 like 11. (200 aa)
H1-8H1 histone family member O oocyte specific. (299 aa)
UNC5AUnc-5 netrin receptor A. (818 aa)
SEPTIN4-2Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (494 aa)
PSMA5Proteasome subunit alpha type. (128 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
OMA1OMA1 zinc metallopeptidase. (524 aa)
ENSPCOP00000025404Uncharacterized protein. (202 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PTK2Protein tyrosine kinase 2. (1089 aa)
DIABLOUncharacterized protein. (168 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (278 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (268 aa)
DFFADNA fragmentation factor subunit alpha. (331 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (692 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
HP1BP3Heterochromatin protein 1 binding protein 3. (499 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMA2Proteasome subunit alpha type. (245 aa)
DBNLDrebrin like. (431 aa)
ENSPCOP00000027105Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BMXTyrosine-protein kinase. (627 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
LOC105816759Ubiquitin-like domain-containing protein. (156 aa)
SDCBPUncharacterized protein. (298 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
LOC105807375Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
GZMBPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (269 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
MAPK8Mitogen-activated protein kinase 8. (346 aa)
LOC105823889Uncharacterized protein. (214 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC105812072Uncharacterized protein. (187 aa)
APCAPC regulator of WNT signaling pathway. (2844 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ARHGAP10Rho GTPase activating protein 10. (768 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (249 aa)
CHMP2BUncharacterized protein. (113 aa)
PSMD4Proteasome 26S subunit, non-ATPase 4. (380 aa)
PSMB7Proteasome subunit beta. (277 aa)
ENSPCOP00000029247Proteasome subunit beta; Belongs to the peptidase T1B family. (257 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (406 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
STAT3Signal transducer and activator of transcription. (796 aa)
ENSPCOP00000030477PDZ domain-containing protein. (263 aa)
ENSPCOP00000030534Uncharacterized protein. (49 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (256 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
GSDMDGasdermin D. (545 aa)
PSMB8Proteasome subunit beta. (276 aa)
BADBCL2 associated agonist of cell death. (168 aa)
SEPTIN1Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (406 aa)
NMT1Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (496 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (816 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (665 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (620 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (516 aa)
LOC105822171CARD domain-containing protein. (98 aa)
ENSPCOP00000031317Uncharacterized protein. (70 aa)
PSME2Proteasome activator subunit 2. (253 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (385 aa)
ENSPCOP00000031861Uncharacterized protein. (214 aa)
LOC105815609Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (220 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
Server load: low (20%) [HD]