STRINGSTRING
LOC105824103 LOC105824103 USP31 USP31 POLK POLK POLE3 POLE3 POLE2 POLE2 TRIM65 TRIM65 RFC2 RFC2 UBA7 UBA7 RFC1 RFC1 LOC105816759 LOC105816759 TRIM47 TRIM47 TRIM25 TRIM25 UBE2L6 UBE2L6 POLD3 POLD3 POLD2 POLD2 ENSPCOP00000023542 ENSPCOP00000023542 POLD4 POLD4 RCBTB1 RCBTB1 RPA3 RPA3 POLI POLI RCBTB2 RCBTB2 RPA1 RPA1 MEIOB MEIOB LOC105820322 LOC105820322 UBA52 UBA52 REV1 REV1 PCLAF PCLAF USP10 USP10 ENSPCOP00000008190 ENSPCOP00000008190 PCNA PCNA POLH POLH POLE4 POLE4 ATAD5 ATAD5 ISG15 ISG15 USP43 USP43 ENSPCOP00000012718 ENSPCOP00000012718 POLE POLE POLD1 POLD1 RFC3 RFC3 RPS27A RPS27A RFC4 RFC4 RFC5 RFC5 ENSPCOP00000018904 ENSPCOP00000018904
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105824103Uncharacterized protein. (430 aa)
USP31Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1345 aa)
POLKDNA polymerase kappa. (832 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
POLE2DNA polymerase epsilon 2, accessory subunit. (439 aa)
TRIM65Tripartite motif containing 65. (515 aa)
RFC2Replication factor C subunit 2. (352 aa)
UBA7Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1008 aa)
RFC1Replication factor C subunit 1. (1113 aa)
LOC105816759Ubiquitin-like domain-containing protein. (156 aa)
TRIM47Tripartite motif containing 47. (638 aa)
TRIM25Tripartite motif containing 25. (633 aa)
UBE2L6Ubiquitin conjugating enzyme E2 L6. (90 aa)
POLD3DNA polymerase delta 3, accessory subunit. (359 aa)
POLD2DNA polymerase delta 2, accessory subunit. (504 aa)
ENSPCOP00000023542Ubiquitin-like domain-containing protein. (112 aa)
POLD4Uncharacterized protein. (107 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RPA3Replication protein A3. (107 aa)
POLIDNA polymerase iota. (735 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
MEIOBMeiosis specific with OB-fold. (289 aa)
LOC105820322Ubiquitin-like domain-containing protein. (77 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1197 aa)
PCLAFPAF domain-containing protein. (65 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (798 aa)
ENSPCOP00000008190AAA domain-containing protein. (331 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
POLHDNA polymerase eta. (709 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (118 aa)
ATAD5ATPase family AAA domain containing 5. (1646 aa)
ISG15ISG15 ubiquitin like modifier. (174 aa)
USP43Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1122 aa)
ENSPCOP00000012718Ubiquitin-like domain-containing protein. (74 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa)
POLD1DNA polymerase. (1125 aa)
RFC3Replication factor C subunit 3. (356 aa)
RPS27ARibosomal protein S27a. (156 aa)
RFC4Replication factor C subunit 4. (365 aa)
RFC5AAA domain-containing protein. (338 aa)
ENSPCOP00000018904Ubiquitin-like domain-containing protein. (131 aa)
Your Current Organism:
Propithecus coquereli
NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli
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