43 items (Propithecus coquereli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105824103	Uncharacterized protein. (430 aa)
	USP31	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1345 aa)
	POLK	DNA polymerase kappa. (832 aa)
	POLE3	DNA polymerase epsilon 3, accessory subunit. (147 aa)
	POLE2	DNA polymerase epsilon 2, accessory subunit. (439 aa)
	TRIM65	Tripartite motif containing 65. (515 aa)
	RFC2	Replication factor C subunit 2. (352 aa)
	UBA7	Ubiquitin like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1008 aa)
	RFC1	Replication factor C subunit 1. (1113 aa)
	LOC105816759	Ubiquitin-like domain-containing protein. (156 aa)
	TRIM47	Tripartite motif containing 47. (638 aa)
	TRIM25	Tripartite motif containing 25. (633 aa)
	UBE2L6	Ubiquitin conjugating enzyme E2 L6. (90 aa)
	POLD3	DNA polymerase delta 3, accessory subunit. (359 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (504 aa)
	ENSPCOP00000023542	Ubiquitin-like domain-containing protein. (112 aa)
	POLD4	Uncharacterized protein. (107 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (531 aa)
	RPA3	Replication protein A3. (107 aa)
	POLI	DNA polymerase iota. (735 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (616 aa)
	MEIOB	Meiosis specific with OB-fold. (289 aa)
	LOC105820322	Ubiquitin-like domain-containing protein. (77 aa)
	UBA52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (232 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1197 aa)
	PCLAF	PAF domain-containing protein. (65 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (798 aa)
	ENSPCOP00000008190	AAA domain-containing protein. (331 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	POLH	DNA polymerase eta. (709 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (118 aa)
	ATAD5	ATPase family AAA domain containing 5. (1646 aa)
	ISG15	ISG15 ubiquitin like modifier. (174 aa)
	USP43	Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family. (1122 aa)
	ENSPCOP00000012718	Ubiquitin-like domain-containing protein. (74 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2284 aa)
	POLD1	DNA polymerase. (1125 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RPS27A	Ribosomal protein S27a. (156 aa)
	RFC4	Replication factor C subunit 4. (365 aa)
	RFC5	AAA domain-containing protein. (338 aa)
	ENSPCOP00000018904	Ubiquitin-like domain-containing protein. (131 aa)

Your Current Organism:

Propithecus coquereli

NCBI taxonomy Id: 379532
Other names: P. coquereli, Propithecus verreauxi coquereli

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	ENSPCOP00000008190	ENSPCOP00000011601	ENSPCOP00000008190	ATPase family AAA domain containing 5.	AAA domain-containing protein.	0.986
ATAD5	ENSPCOP00000012718	ENSPCOP00000011601	ENSPCOP00000012718	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.557
ATAD5	ENSPCOP00000018904	ENSPCOP00000011601	ENSPCOP00000018904	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.640
ATAD5	ISG15	ENSPCOP00000011601	ENSPCOP00000012018	ATPase family AAA domain containing 5.	ISG15 ubiquitin like modifier.	0.557
ATAD5	LOC105816759	ENSPCOP00000011601	ENSPCOP00000027379	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.640
ATAD5	LOC105820322	ENSPCOP00000011601	ENSPCOP00000003549	ATPase family AAA domain containing 5.	Ubiquitin-like domain-containing protein.	0.557
ATAD5	MEIOB	ENSPCOP00000011601	ENSPCOP00000000779	ATPase family AAA domain containing 5.	Meiosis specific with OB-fold.	0.882
ATAD5	PCLAF	ENSPCOP00000011601	ENSPCOP00000004804	ATPase family AAA domain containing 5.	PAF domain-containing protein.	0.649
ATAD5	PCNA	ENSPCOP00000011601	ENSPCOP00000008972	ATPase family AAA domain containing 5.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.992
ATAD5	POLD1	ENSPCOP00000011601	ENSPCOP00000015021	ATPase family AAA domain containing 5.	DNA polymerase.	0.883
ATAD5	POLD2	ENSPCOP00000011601	ENSPCOP00000023689	ATPase family AAA domain containing 5.	DNA polymerase delta 2, accessory subunit.	0.772
ATAD5	POLE	ENSPCOP00000011601	ENSPCOP00000014601	ATPase family AAA domain containing 5.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.935
ATAD5	POLE2	ENSPCOP00000011601	ENSPCOP00000029196	ATPase family AAA domain containing 5.	DNA polymerase epsilon 2, accessory subunit.	0.878
ATAD5	POLE3	ENSPCOP00000011601	ENSPCOP00000029327	ATPase family AAA domain containing 5.	DNA polymerase epsilon 3, accessory subunit.	0.832
ATAD5	POLE4	ENSPCOP00000011601	ENSPCOP00000011084	ATPase family AAA domain containing 5.	DNA polymerase epsilon 4, accessory subunit.	0.791
ATAD5	POLH	ENSPCOP00000011601	ENSPCOP00000009689	ATPase family AAA domain containing 5.	DNA polymerase eta.	0.759
ATAD5	POLI	ENSPCOP00000011601	ENSPCOP00000021093	ATPase family AAA domain containing 5.	DNA polymerase iota.	0.715
ATAD5	POLK	ENSPCOP00000011601	ENSPCOP00000029619	ATPase family AAA domain containing 5.	DNA polymerase kappa.	0.719
ATAD5	REV1	ENSPCOP00000011601	ENSPCOP00000004714	ATPase family AAA domain containing 5.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.730
ATAD5	RFC1	ENSPCOP00000011601	ENSPCOP00000027556	ATPase family AAA domain containing 5.	Replication factor C subunit 1.	0.767